Blindness News and Research

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Gene therapy restores vision in patients with rare congenital blindness

In a clinical trial at The Children's Hospital of Philadelphia, researchers from The University of Pennsylvania have used gene therapy to safely restore vision in three young adults with a rare form of congenital blindness.

27 Apr 2008

Study shows factors influencing premature infant survival, disability

Based on observations of more than 4,000 infants, researchers in an NIH newborn research network have identified several factors that influence an extremely low birth weight infant's chances for survival and disability. The findings offer new information to physicians and families considering the most appropriate treatment options for this category of infants.

17 Apr 2008

New vector carries big genes linked to inherited blindness

Some clinicians and researchers hope that individuals with inherited diseases (such as cystic fibrosis and recessive Stargardt disease, which causes progressive loss of sight) might one day be cured by providing them with a corrected version of their disease-causing faulty gene, i.e., by gene therapy.

16 Apr 2008

Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

Scientists at the Toronto General Hospital Research Institute have discovered a novel signaling pathway between three organs - the gut, the brain, and the liver - which lowers blood sugar when activated.

10 Apr 2008

PAHEF discusses neglected diseases and disaster preparedness with innovative leaders

PAHEF is pleased to join Harvard University's Ash Institute for Democratic Governance and Innovation as a partner in the bi-annual conference Frontiers of Innovation: 20 Years of Innovation in Government held in Cambridge March 31st through today.

4 Apr 2008

Older corneas suitable for transplantation

The age pool of corneas for transplant should be expanded to include donors up to 75 years of age, based on findings from a study funded by the National Eye Institute (NEI), one of the National Institutes of Health (NIH).

2 Apr 2008

New genetic clues to diabetes

An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.

1 Apr 2008

New genetic clues to diabetes

31 Mar 2008

Type 2 diabetes genes linked with prostate cancer

Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer.

31 Mar 2008

Experts call for a global fund to combat neglected tropical diseases

An international team of tropical disease control experts has urged the global health and development community, and particularly the G8 leaders, to establish a new financing mechanism to combat the neglected tropical diseases (NTDs) of poverty.

28 Mar 2008

Illicit drug use and risky sex fueling rise in syphilis

According to researchers in the U.S. syphilis which was almost eradicated a decade ago in the developed world, is making a comeback.

19 Mar 2008

New hope for victims of macular degeneration and retinitis pigmentosa

Scientists at Schepens Eye Research Institute have discovered what chemical in the eye triggers the dormant capacity of certain non-neuronal cells to transform into progenitor cells, a stem-like cell that can generate new retinal cells.

19 Mar 2008

Compound present naturally in grape skin fights the complications of diabetes

Research carried out by scientists at the Peninsula Medical School in the South West of England has found that resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes, according to a paper published in the science journal "Diabetes, Obesity and Metabolism" this week.

19 Mar 2008

At home genomic tests for disease risk may be premature

The recent marketing of "at home" genomic tests for disease risk may be premature, according to Dr. Kenneth Offit, MD, MPH, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering Cancer Center (MSKCC).

19 Mar 2008

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity.

17 Mar 2008

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice

Two major eye diseases and leading causes of blindness—age-related macular degeneration and diabetic retinopathy can be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other institutions have announced in a new study.

17 Mar 2008

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

12 Mar 2008

Glaucoma associated with increased risk of cardiovascular death in black patients

In a population of African origin, persons with diagnosed and treated glaucoma appeared to have an increased risk of death from cardiovascular causes, according to a study by Suh-Yuh Wu, and colleagues in the Departments of Preventive Medicine and Ophthalmology at Stony Brook University, the University of the West Indies, and the Cleveland Clinic Foundation.

12 Mar 2008

Weight-loss more effective than intensive insulin therapy for type 2 diabetics, according to expert

11 Mar 2008

Glaucoma associated with increased risk of cardiovascular death in black patients

Black patients with diagnosed and treated glaucoma and those with high pressure in their eyes appear to have an increased risk of death from cardiovascular causes, according to a report in the March issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Mar 2008

Blindness News and Research

Gene therapy restores vision in patients with rare congenital blindness

Study shows factors influencing premature infant survival, disability

New vector carries big genes linked to inherited blindness

Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

PAHEF discusses neglected diseases and disaster preparedness with innovative leaders

Older corneas suitable for transplantation

New genetic clues to diabetes

New genetic clues to diabetes

Type 2 diabetes genes linked with prostate cancer

Experts call for a global fund to combat neglected tropical diseases

Illicit drug use and risky sex fueling rise in syphilis

New hope for victims of macular degeneration and retinitis pigmentosa

Compound present naturally in grape skin fights the complications of diabetes

At home genomic tests for disease risk may be premature

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Glaucoma associated with increased risk of cardiovascular death in black patients

Weight-loss more effective than intensive insulin therapy for type 2 diabetics, according to expert

Glaucoma associated with increased risk of cardiovascular death in black patients

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