Clinical Trial News and Research

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New tool can diagnose autism in children as young as 16 months

Results of clinical studies published simultaneously today in the Journal of the American Medical Association (JAMA) and in JAMA Network Open demonstrate that measuring children's looking behavior predicts expert clinical diagnosis of autism in children between ages 16 to 30 months tested with a high degree of accuracy.

5 Sep 2023

What are the efficacy and safety of psilocybin in patients with major depressive disorder?

The safety, timing, magnitude, and durability of the antidepressant psilocybin on patients with major depressive disorders.

4 Sep 2023

New breakthroughs by NPL scientists could transform cancer treatment

New breakthroughs by scientists at the National Physical Laboratory (NPL) are set to transform cancer treatment in the UK and worldwide.

4 Sep 2023

UVA Health receives NIH grant for testing radical new approach to managing type 2 diabetes

The National Institutes of Health has provided $3.5 million for a large-scale clinical trial testing a radical new approach to managing type 2 diabetes that, in an earlier study, put almost 70% of participants in remission without weight loss or medication.

4 Sep 2023

Ohio State University launches first-in-world clinical trial of heart failure device

The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.

4 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Scientists discover new role for liver tPA in regulating cholesterol levels

Despite advances in treatment for high cholesterol, heart disease remains the leading cause of death in the U.S. Scientists at the Medical College of Wisconsin (MCW) are investigating the role of a form of cholesterol called very-low-density lipoprotein – and their findings may lead to new treatment options in the future.

1 Sep 2023

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) cediranib did not make a difference in outcomes for treating patients with an advanced form of thyroid cancer that develops from thyroid follicular cells called differentiated thyroid cancer (DTC).

1 Sep 2023

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

News Medical interviewed Dr Paula Desplats, an Associate Professor of Neurosciences at the University of California San Diego.

1 Sep 2023

Redo TAVR procedures are safe and effective, study shows

Cedars-Sinai investigators are leaders in the innovation and use of transcatheter aortic valve replacement (TAVR) with balloon-expandable valves.

31 Aug 2023

New gene therapy offers hope for beta thalassemia patients

UCSF Benioff Children's Hospital Oakland provides new therapy to first patient since FDA approval.

31 Aug 2023

MFGM supplement in infant formula linked to long-term cognitive benefits

Breast milk is widely acknowledged as the most beneficial nutrition for infants, but many families face medical or logistical challenges in breastfeeding. In the U.S., just 45% of infants continue to be exclusively breastfed at 3 months of age, according to the Centers for Disease Control.

31 Aug 2023

Peer-delivered psychotherapy effective for postpartum depression

An innovative model of care that offers new mothers psychotherapy delivered by other mothers who have also experienced post-partum depression (PPD) should be implemented in clinical practice, according to researchers at McMaster University.

31 Aug 2023

Impact of vaping high CBD/low THC products on driving ability

Researchers assess how cannabinoid levels in the blood affect driving after single or repetitive vaporization of cannabis rich in CBD.

31 Aug 2023

Home monitoring of ovulation as effective as hospital checks for IVF

Home monitoring of ovulation prior to placing frozen embryos during an IVF process works just as well as hospital checks to determine the best time.

30 Aug 2023

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

New research published in the New England Journal of Medicine indicates that stem cell gene therapy may offer a promising, curative treatment for the painful, inherited blood disorder sickle cell disease (SCD).

30 Aug 2023

Study finds potential HIV cure using existing cancer drug

An existing blood cancer drug has shown promise in killing 'silent' HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.

30 Aug 2023

UQ-led clinical trial to test the effectiveness of diabetes drug for polycystic kidney disease

Patient recruitment is underway for a University of Queensland-led clinical trial to test the effectiveness of a diabetes drug to slow the progression of polycystic kidney disease (PKD).

30 Aug 2023

New oral agent shows promise in treatment of relapsed multiple myeloma

A new agent that subverts myeloma cells from within while also subjecting them to an immune system attack produced impressive responses in combination with dexamethasone in patients with multiple myeloma that had relapsed and stopped responding to all currently available therapies, a clinical trial conducted by researchers at Dana-Farber Cancer Institute and around the world has found.

30 Aug 2023

Clinical Trial News and Research

New tool can diagnose autism in children as young as 16 months

What are the efficacy and safety of psilocybin in patients with major depressive disorder?

New breakthroughs by NPL scientists could transform cancer treatment

UVA Health receives NIH grant for testing radical new approach to managing type 2 diabetes

Ohio State University launches first-in-world clinical trial of heart failure device

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Scientists discover new role for liver tPA in regulating cholesterol levels

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

Redo TAVR procedures are safe and effective, study shows

New gene therapy offers hope for beta thalassemia patients

MFGM supplement in infant formula linked to long-term cognitive benefits

Peer-delivered psychotherapy effective for postpartum depression

Impact of vaping high CBD/low THC products on driving ability

Home monitoring of ovulation as effective as hospital checks for IVF

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

Study finds potential HIV cure using existing cancer drug

UQ-led clinical trial to test the effectiveness of diabetes drug for polycystic kidney disease

New oral agent shows promise in treatment of relapsed multiple myeloma

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