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Breakthrough research reveals how to target malignant DNA in aggressive cancers

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

9 Nov 2024

Genetic diagnosis solves medical mystery for 30 undiagnosed patients

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

8 Nov 2024

New discovery could lead to better treatments for drug-resistant leukemia

Scientists from Duke-NUS Medical School and their collaborators have identified an inherited genetic variation prevalent among East Asians that contributes to drug resistance, driving the aggressive growth of cancer cells in patients with chronic myeloid leukemia.

8 Nov 2024

MIT team creates efficient technique for identifying causal gene relationships

By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand the development of certain diseases.

8 Nov 2024

HNL Dimer as a promising biomarker for monitoring antibiotic treatment in sepsis

The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.

8 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

Mpox vaccine allocation targets 9 African countries

The Access and Allocation Mechanism (AAM) for mpox has allocated an initial 899 000 vaccine doses for 9 countries across the African region that are hit hard by the current mpox surge.

7 Nov 2024

Understanding gut microbial imbalance in pancreatic cancer development and treatment

Pancreatic ductal adenocarcinoma (PDAC) is recognized as one of the most lethal cancers, with an estimated five-year survival rate of approximately 10%.

7 Nov 2024

New SCLC biomarkers enable advances in precision medicine approaches

A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC"

6 Nov 2024

Electric fans ease heart strain for older adults in humid heat

New collaborative research from the University of Sydney and the Montreal Heart Institute has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US.

6 Nov 2024

Stanford researchers unveil the key role of extrachromosomal DNA in cancer

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles - until recently dismissed as inconsequential - are major drivers of many types of human cancers.

6 Nov 2024

Brain cells form multiple coordinate systems to guide behavioral actions

Neuroscientists have discovered brain cells that form multiple coordinate systems to tell us "where we are" in a sequence of behaviors.

6 Nov 2024

Study uncovers how certain E. coli bacteria in the gut promote colon cancer

Scientists have uncovered how certain E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin.

6 Nov 2024

Nanoscale sensor detects lung cancer through breath chemistry

Exhaled breath contains chemical clues to what's going on inside the body, including diseases like lung cancer.

6 Nov 2024

Solascure and U.S. Army Institute of Surgical Research collaborate for combat wound care

SOLASCURE Ltd ("SolasCure"), a biotechnology company developing a novel treatment to transform chronic wound care and the U.S. Army Institute of Surgical Research ("USAISR"), today announced a research collaboration to evaluate SolasCure's investigational product, Aurase Wound Gel, as a means for managing combat wounds.

From SolasCure 6 Nov 2024

New insights into the role of innate immunity in tumor initiation

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways - ways that have important implications for the development of cancer, researchers at Memorial Sloan Kettering Cancer Center (MSK) are discovering.

5 Nov 2024

New research uncovers 16 genes that aid breast cancer survival

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they've escaped the low-oxygen regions of a tumor.

5 Nov 2024

Consortium receives 10 million euros to study in vivo tissue mechanics

The European Research Council is funding a consortium consisting of the Helmholtz-Zentrum Hereon, ETH Zurich and TU Graz with a total of 10 million euros for developing new methods to determine the mechanical properties of living human tissue.

5 Nov 2024

A quick return to school and light exercise may help kids recover from concussions

During cheerleading practice in April, Jana Duey's sixth grade daughter, Karter, sustained a concussion when she fell several feet headfirst onto a gym floor mat. Days after, Karter still had a headache, dizziness, and sensitivity to light and noise.

5 Nov 2024

Werner syndrome gene plays key role in maintaining cellular organization and DNA stability

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells."

5 Nov 2024