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Scientists discover major regulator of schizophrenia that is active during early development

Researchers have discovered a gene that acts as a master regulator of schizophrenia during the early stages of human brain development.

12 Sep 2019

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

University of Colorado Boulder engineers and faculty from the Consortium for Fibrosis Research & Translation at the University of Colorado Anschutz Medical Campus have teamed up to develop biomaterial-based "mimics" of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery.

12 Sep 2019

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

In this interview, Dr. Dave Fancy, CEO of Jackson ImmunoResearch explains how anti-VHH antibodies can be used to produce nanobodies and VHH libraries.

From Jackson ImmunoResearch Laboratories, Inc. 12 Sep 2019

New gold-based molecules more effective at killing cancer cells with fewer toxic side effects

Researchers have engineered gold-based molecules that target cancer cells and leave healthy cells unharmed, in a critical step towards precision cancer drugs with fewer toxic side effects.

6 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

New advance could lead to regrowth of decayed enamel

Modern dental practice is concerned with preserving teeth rather than extracting them, even if tooth decay is present. Various types of fillings have been used, including materials like composite resins, ceramics and amalgams.

3 Sep 2019

Discovery may help identify signs of type 1 diabetes earlier

A new study showed that there are significant differences in the MHC class II antigens on the insulin peptide that is deficient in type 1 diabetes mellitus (T1DM). These determine the response of the T cells to the insulin peptide that causes destruction of insulin.

2 Sep 2019

DNA vaccine for tick-borne disease ‘SFTS’ confers protection against lethal infection in ferrets

A KAIST research team reported the development of a DNA vaccine for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) which completely protects against lethal infection in ferrets.

29 Aug 2019

Potential drug could revolutionize the treatment of neurological conditions

The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons.

28 Aug 2019

'MasSpec Pen' could help distinguish between cancerous and healthy tissue during surgery

A major challenge for cancer surgeons is to determine exactly where a tumor starts and where it ends. Removing too much tissue can impair normal functions, but not taking enough can mean the disease could recur.

28 Aug 2019

Traumatic brain injuries could be healed using peptide hydrogels

Traumatic brain injury (TBI) –– defined as a bump, blow or jolt to the head that disrupts normal brain function –– sent 2.5 million people in the U.S. to the emergency room in 2014, according to statistics from the U.S. Centers for Disease Control and Prevention.

27 Aug 2019

Skin patch delivers melanoma medication in one minute

Researchers have developed a fast-acting skin patch that can deliver medication to treat melanoma in one minute.

26 Aug 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Reliable response of cortical neurons amidst noise and chaos

Neurons communicate with each other by sending out rapid pulses of electrical signals called spikes. At first glance, the generation of these spikes can be very reliable: when an isolated neuron is repeatedly given exactly the same electrical input, we find the same pattern of spikes.

22 Aug 2019

Virginia Tech professor wins NSF grant to study biofilm formation in bacteria

Should I stay or should I go? This is a common question people ask themselves in their journey through life, but bacteria are also asking the same question.

22 Aug 2019

New insights into protein transport could help define strategies for treating eye disease

Many forms of vision loss stem from a common source: impaired communication between the eye and the brain. And at the root of all eye-to-brain communication are the hundreds of proteins generated by the retina's nerve cells.

22 Aug 2019

New cannabis-based drug shows promise for pancreatic cancer

Cancer of the pancreas is a particularly deadly cancer, claiming over 90% of its victims within 5 years from diagnosis. It resists most standard therapies, including surgery, chemotherapy, radiation therapy, immunotherapy and targeted therapy, and metastasizes early, often before being diagnosed. A cure is possible only with very localized tumors.

22 Aug 2019

FDA approves cold atmospheric plasma technology for first-ever use in clinical trial

Cold atmospheric plasma technology, currently the only way to remove microscopic cancer tumors remaining from surgery, has been approved by the U.S. Food and Drug Administration for first-ever use in a clinical trial.

20 Aug 2019

Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer

Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread.

19 Aug 2019

in vivo News and Research

Scientists discover major regulator of schizophrenia that is active during early development

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

Accelerating Nanobody Production using Polyclonal Anti-VHH Antibodies

New gold-based molecules more effective at killing cancer cells with fewer toxic side effects

Researchers discover a molecule that regulates tumor development in different types of cancers

Melatonin promises to help reduce bone loss in space flight

New advance could lead to regrowth of decayed enamel

Discovery may help identify signs of type 1 diabetes earlier

DNA vaccine for tick-borne disease ‘SFTS’ confers protection against lethal infection in ferrets

Potential drug could revolutionize the treatment of neurological conditions

'MasSpec Pen' could help distinguish between cancerous and healthy tissue during surgery

Traumatic brain injuries could be healed using peptide hydrogels

Skin patch delivers melanoma medication in one minute

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

Reliable response of cortical neurons amidst noise and chaos

Virginia Tech professor wins NSF grant to study biofilm formation in bacteria

New insights into protein transport could help define strategies for treating eye disease

New cannabis-based drug shows promise for pancreatic cancer

FDA approves cold atmospheric plasma technology for first-ever use in clinical trial

Study shows synergistic effects of drugs that inhibit cell division in pancreatic cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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