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New study on propofol drug may help develop effective anesthetics with fewer side effects

Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.

23 Sep 2013

FDA takes action to prevent food distribution from rodent and insect-infested facility

U.S. Marshals seized food products at Gourmet Provisions, LLC and Royal Cup, Inc., after U.S. Food and Drug Administration investigators found widespread and active rodent and insect infestation on the premises.

21 Sep 2013

Research roundup: 'Cadillac' plan taxes; 'chronic care management' for substance abusers; long-term care services

As health coverage expands to tens of millions of Americans--through Medicaid expansion in states and the new state health insurance exchanges that will soon begin selling individual health coverage--some Americans with employer-sponsored health coverage are seeing their benefits decrease.

21 Sep 2013

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

The University of North Carolina at Chapel Hill received two separate grants from the U.S. Food and Drug Administration and the National Institutes of Health today as part of an on-going interagency partnership. UNC will house two of 14 Tobacco Centers of Regulatory Science, which are receiving a total of up to $53 million for tobacco-related research in fiscal year 2013.

21 Sep 2013

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

A dual-degree program combining a doctorate in pharmacy with a medical degree has been developed by Rutgers University's Robert Wood Johnson Medical School and Ernest Mario School of Pharmacy.

21 Sep 2013

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin analogs and phosphodiesterase 5 inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension.

21 Sep 2013

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

Janssen Pharmaceuticals, Inc. announced today a newly published, pooled analysis of the Phase III EINSTEIN trial program, showing XARELTO (rivaroxaban) is as effective as the standard of care in reducing the risk of deep vein thrombosis and pulmonary embolism in people with symptomatic DVT or PE, while reducing the incidence of major bleeding by 46 percent.

21 Sep 2013

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.

21 Sep 2013

FDA announces final rule for UDI system to identify medical devices

Today, the U.S. Food and Drug Administration announced a final rule for the unique device identification system that, once implemented, will provide a consistent way to identify medical devices.

21 Sep 2013

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

Applied Integrin Sciences, Inc. announced today that its first cancer therapeutic drug candidate eliminated all intraperitoneal ovarian cancer tumors in a pre-clinical study testing a novel treatment regimen.

21 Sep 2013

Researchers make new breakthroughs in brain circuitry controlling fertility

In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.

21 Sep 2013

DiaRem score predicts diabetes remission after gastric bypass

A new scoring system offers a “scientifically valid” way of predicting the 5-year likelihood for diabetes remission in patients undergoing gastric bypass surgery, say the researchers who developed the score.

20 Sep 2013

FDA, NIH awarded $53 million to create 14 Tobacco Centers of Regulatory Science

The U.S. Food and Drug Administration and the National Institutes of Health today, as part of an on-going interagency partnership, have awarded a total of up to $53 million to fund tobacco-related research in fiscal year 2013 to create 14 Tobacco Centers of Regulatory Science.

20 Sep 2013

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Researchers at Weill Cornell Medical College have discovered why a tiny alteration in a brain gene, found in 20 percent of the population, contributes to the risk for anxiety, depression and memory loss.

20 Sep 2013

Reprieve over? Health spending projected to climb 6% next year

The nation's health care spending is slated to rise about 6 percent next year, according to a new Centers for Medicare & Medicaid Services report. This follows five years of slower growth expected to end as the nation's economy recovers and the health law expands coverage. The spending increase is likely lower than it would have been, however, if the Supreme Court hadn't allowed states to choose whether to expand Medicaid, researchers wrote.

20 Sep 2013

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Genetic tests can now tell us whether we are at increased risk of various cancers, heart or kidney disease, asthma and a number of other conditions.

20 Sep 2013

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

20 Sep 2013

Human breast tumors transplant could be valuable tools in search for better treatments

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.

20 Sep 2013

Clinical trial by Moffitt to reduce risk of prostate cancer in black men

Prostate cancer kills more African-American and black men than any other group. Yet, according to a new review published by Moffitt Cancer Center researchers, there is a significant lack of clear and consistent screening and early detection guidelines or prevention strategies.

20 Sep 2013

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene.

20 Sep 2013

Drugs News and Research

New study on propofol drug may help develop effective anesthetics with fewer side effects

FDA takes action to prevent food distribution from rodent and insect-infested facility

Research roundup: 'Cadillac' plan taxes; 'chronic care management' for substance abusers; long-term care services

UNC receives grants from FDA and NIH to establish Tobacco Centers of Regulatory Science

Ernest Mario School of Pharmacy, Robert Wood Johnson Medical School to launch dual-degree program

PGI2 analogs, PDE5 inhibitors stimulate enhanced release of vasodilator ATP from human RBCs

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

MIT researchers develop microfluidic device that mimics flow of cancer cells through blood vessels

FDA announces final rule for UDI system to identify medical devices

Applied Integrin Sciences' drug candidate eliminates ovarian cancer tumors in pre-clinical study

Researchers make new breakthroughs in brain circuitry controlling fertility

DiaRem score predicts diabetes remission after gastric bypass

FDA, NIH awarded $53 million to create 14 Tobacco Centers of Regulatory Science

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Reprieve over? Health spending projected to climb 6% next year

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Human breast tumors transplant could be valuable tools in search for better treatments

Clinical trial by Moffitt to reduce risk of prostate cancer in black men

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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