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New method to target, eliminate cancer-supporting macrophages in mouse tumors

When a person has cancer, some of the cells in his or her body have changed and are growing uncontrollably. Most cancer drugs try to treat the disease by killing those fast-growing cells, but another approach called immunotherapy tries to stimulate a person's own immune system to attack the cancer itself.

17 Sep 2013

Acacia Pharma initiates two pivotal Phase 3 studies of APD421 in prevention of PONV

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces the initiation of two pivotal Phase 3 studies of APD421 in the prevention of post-operative nausea & vomiting (PONV).

17 Sep 2013

Research finding offers new approach to treating melanoma

Scientists at Sanford-Burnham Medical Research Institute today announced the discovery that a gene encoding an enzyme, phosphoinositide-dependent kinase-1, plays an essential role in the development and progression of melanoma. The finding offers a new approach to treating this life-threatening disease.

17 Sep 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Varenicline drug helps people with depression quit smoking, say researchers

About half of smokers seeking treatment for smoking cessation have a history of depression. Compared with smokers who are not depressed, those who suffer from a major depressive disorder have greater difficulty quitting.

17 Sep 2013

State highlights: Analysis finds no imminent patient danger before Texas abortion law; N.M. fraud investigation disrupts mental health care

In their successful push this summer for strict new regulations on abortion facilities and the doctors performing them, proponents said the legislation was needed because conditions at existing facilities made it unsafe for women seeking to terminate pregnancies. But a Texas Tribune review of state inspection records for 36 abortion clinics from the year preceding the lawmakers' vote turned up little evidence to suggest that the facilities were putting patients in imminent danger.

17 Sep 2013

Flecainide, encainide drugs increase risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

17 Sep 2013

Researchers develop new variety of corked microbottle for drugs

Sustained-release formulations that release drugs over longer periods of time are not the final step in the evolution of “intelligent” drug delivery systems. Modern pharmaceuticals are being designed to be released only in a specific, diseased organ; on cues from our circadian rhythm; or under specific physiological conditions.

17 Sep 2013

Viewpoints: GOP willing to move to default if they can't cripple health law; it's time to figure out if workplace wellness programs work

This year, as has been the case so often in the past, their target is President Obama's health care reform law. If it is not repealed or defunded or delayed or otherwise left bleeding in the public square, they will not pass a spending bill needed to keep the government open past Sept. 30. And if that doesn't cripple the health law (which it won't), they will resort to the far more serious threat of default, refusing to raise the nation's debt ceiling, no matter the catastrophe that would cause (9/14).

17 Sep 2013

Understanding essential role of gut microbes in immune system

A new understanding of the essential role of gut microbes in the immune system may hold the key to dealing with some of the more significant health problems facing people in the world today, Oregon State University researchers say in a new analysis.

17 Sep 2013

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.

17 Sep 2013

FDA issues import alert on drug products manufactured at Ranbaxy's facility in Mohali, India

The U.S. Food and Drug Administration today issued an import alert under which U.S. officials may detain at the U.S. border drug products manufactured at Ranbaxy Laboratories, Ltd.'s facility in Mohali, India.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

First generic version of Xeloda gets FDA approval for breast and colorectal cancers

The U.S. Food and Drug Administration today approved the first generic version of Xeloda (capecitabine), an oral chemotherapy pill used to treat cancer of the colon or rectum (colorectal cancer) that has spread to other parts of the body (metastatic), and metastatic breast cancer.

17 Sep 2013

Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

In the general population, current smoking prevalence is 18%. Persons living with HIV/AIDS smoke at a rate 2 to 3 times higher, up to almost 70% in some studies.

16 Sep 2013

First Edition: September 16, 2013

Today's headlines include reports about new polling indicating that the health law still faces an uphill climb.

16 Sep 2013

Kinder chemistry promises cleaner and safer pharmaceuticals with fewer side-effects

A new and kinder chemistry promises cleaner and subsequently safer pharmaceuticals with fewer side-effects. The ground-breaking method, developed by a chemistry research group at the University of Copenhagen, is now published in the internationally renowned journal, Chemical Communications, as "Site-selective three component reaction for dual functionalization of peptides".

16 Sep 2013

Electronic data can be used as warning system for missed doses of prescribed medicine

Electronic data routinely gathered in hospitals can be used as a warning system for missed doses of prescribed medicine and making improvements to patient safety, says a new study.

16 Sep 2013

Combination therapies: Cost-effective alternative to treat visceral leishmaniasis

Visceral leishmaniasis is the second-deadliest parasitic disease after malaria. Each year, thousands fall victim among poor and marginalised populations in low-income countries.

16 Sep 2013

Study: Opioid prescribing for non-cancer pain increases

Prescribing of strong opioid medications for non-cancer pain in the United States has nearly doubled over the past decade, reports a study in the October issue of Medical Care, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Sep 2013

Drugs News and Research

New method to target, eliminate cancer-supporting macrophages in mouse tumors

Acacia Pharma initiates two pivotal Phase 3 studies of APD421 in prevention of PONV

Research finding offers new approach to treating melanoma

TSRI scientists find new way to boost effectiveness of anticancer drugs

Varenicline drug helps people with depression quit smoking, say researchers

State highlights: Analysis finds no imminent patient danger before Texas abortion law; N.M. fraud investigation disrupts mental health care

Flecainide, encainide drugs increase risk of sudden cardiac death

Researchers develop new variety of corked microbottle for drugs

Viewpoints: GOP willing to move to default if they can't cripple health law; it's time to figure out if workplace wellness programs work

Understanding essential role of gut microbes in immune system

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

FDA issues import alert on drug products manufactured at Ranbaxy's facility in Mohali, India

Researchers identify new link between meal times and daily changes in immune system

First generic version of Xeloda gets FDA approval for breast and colorectal cancers

Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

First Edition: September 16, 2013

Kinder chemistry promises cleaner and safer pharmaceuticals with fewer side-effects

Electronic data can be used as warning system for missed doses of prescribed medicine

Combination therapies: Cost-effective alternative to treat visceral leishmaniasis

Study: Opioid prescribing for non-cancer pain increases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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