B Cell News and Research

RSS

Targeting PAK5 could offer new therapeutic approach for endometriosis

Endometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the uterus, leading to severe pain and infertility in affected women.

11 Feb 2025

Machine learning tool predicts cancer treatment response based on genetic mutations

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic mutations influence cancer treatment outcomes-insights that could help doctors tailor treatments more effectively.

11 Feb 2025

UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

Scientists discover functional role of introns in cells

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress.

11 Feb 2025

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025

New light-sensitive chemicals show promise for treating aggressive breast cancers

Scientists have developed new light-sensitive chemicals that can radically improve the treatment of aggressive cancers with minimal side effects.

11 Feb 2025

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025

Broccoli sprouts may help prediabetes, but only with the right gut bacteria

Broccoli sprout extract (BSE) modestly lowered fasting blood glucose in prediabetes, but its effectiveness depended on gut microbiota, particularly the BT2160 operon.

11 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

Innovative brain tumor model offers hope for personalized cancer treatments

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.

11 Feb 2025

Lung signals trigger blood clot formation in cancer patients

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.

11 Feb 2025

Breakthrough discovery on tau protein opens new paths for Alzheimer’s drug development

A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau.

11 Feb 2025

Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment

Researchers develop targeted polymersomes loaded with methotrexate for the treatment of gestational choriocarcinoma,

11 Feb 2025

Changes to intermediate filament protein drive aggressive breast cancer growth

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

11 Feb 2025

New mechanism of immune evasion discovered in cancer cells

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

11 Feb 2025

Yale rewrites genetic code for new proteins

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed enabling the production of new classes of synthetic proteins. These synthetic proteins, researchers say, offer the promise of innumerable medical and industrial applications that can benefit society and human health.

11 Feb 2025

New genetic map offers hope for more precise diagnosis and treatment of kidney disease

Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study, published in Science, from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2025

Breakthrough study identifies new way to address Alzheimer's at early stages

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers cellular inflammation and aging and is linked to Alzheimer's disease, particularly among those who carry the APOE4 genetic risk.

10 Feb 2025

Influenza A virus changes shape to evade immune responses

Influenza A virus particles strategically adapt their shape-to become either spheres or larger filaments-to favor their ability to infect cells depending on environmental conditions, according to a new study from National Institutes of Health (NIH) scientists.

10 Feb 2025

Bimagrumab could reduce osteoporosis risk in people using weight loss medication

Weight loss medication has taken the world by storm and helped many overweight people. But for some, significant weight loss also comes with a loss of muscle mass and can lead to an increased risk of osteoporosis.

10 Feb 2025