Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

MRI contrast agent enables early detection of liver disease

Researchers have developed a new MRI contrast dye that enables more accurate and safer detection of early-stage liver disease than currently approved agents.

30 Oct 2019

TDP-43 study could speed up the diagnosis and treatment of ALS

A new study suggests that TDP-43 may be used as a biomarker in the diagnosis and treatment of amyotrophic lateral sclerosis (ALS).

30 Oct 2019

New method helps assess the health of human hair follicles

A variety of factors can stop hair from forming and growing properly, leading to hair diseases and baldness.

30 Oct 2019

Brain function changes could help diagnose and manage depression

Ever heard of the lateral habenula? Very few, outside of neuroscience, probably have. Yet a new study, published in the journal Neuron, shows that characteristic changes in the way this area of the brain fires can result in a total loss of will to do anything – which is characteristic of one form of depression.

29 Oct 2019

First effective noninvasive method for diagnosing early-stage liver diseases

A safer and more sensitive contrast dye for MRI tests developed by a team led by Georgia State University researchers may provide the first effective, noninvasive method for detecting and diagnosing early-stage liver diseases, including liver fibrosis.

29 Oct 2019

Researchers develop new test to detect nutrient deficiencies in harsh environments

Mothers and children in low resource communities may appear well fed but often suffer from micronutrient deficiencies.

29 Oct 2019

Discovery of causal link between hydrogen sulfide and schizophrenia

Researchers from the RIKEN Center for Brain Science in Japan have found certain chemical markers that are associated with schizophrenia. They worked with lab mice with models of schizophrenia as well as post mortem brain specimens of persons with schizophrenia. The study titled, “Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology,” was published in the latest issue of the journal EMBO Molecular Medicine.

28 Oct 2019

Gait disorders can help predict future cognitive decline

The way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to the Journal of Alzheimer's Disease say that gait disorders, particularly slowing gait, should be considered a marker of future cognitive decline.

28 Oct 2019

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Working with model mice, post-mortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain.

28 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

Novel noninvasive imaging technique can provide information about thyroid disorders

A combination of multispectral optoacoustic tomography (MSOT) and ultrasound has been used to noninvasively characterize a range of thyroid disorders, according to new research published in the October issue of The Journal of Nuclear Medicine.

23 Oct 2019

Chronic kidney disease associated with increased risk of adverse cardiovascular outcomes

Chronic kidney disease, which afflicts an estimated 6.4% of U.S. adults 45 and older, is associated with an increased risk of heart attack and other adverse cardiovascular outcomes, according to new research from Mayo Clinic.

23 Oct 2019

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Oncolytics Biotech Inc. , currently developing pelareorep, an intravenously delivered immuno-oncolytic virus, and PrECOG LLC, a leading cancer research network, today announced their collaboration in which PrECOG will run the BRACELET-1 (PrE0113) study.

22 Oct 2019

Quanterix to release third quarter 2019 financial results and host conference call on November 6, 2019

Quanterix announced that it will release its financial results for third quarter 2019 after the close of trading on Wednesday, November 6, 2019.

From Quanterix 22 Oct 2019

Study: High levels of circ E7 is a positive prognostic marker in anal squamous cell carcinoma

High levels of circ E7 by quantitative RT-PCR predicted improved overall survival in ASCC and analysis of The Cancer Genome Atlas sequencing from HPV-positive head and neck cancer and cervical cancer suggested high circ E7 marked improved survival in 875 subjects.

17 Oct 2019

Insilico Medicine presents experimentally validated model for drug discovery at NeurIPS 2019

Insilico Medicine, a biotechnology company developing an end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, is proud to present its paper "A Prior of a Googol Gaussians: a Tensor Ring Induced Prior for Generative Models" at the 33rd Conference on Neural Information Processing Systems (NeurIPS).

16 Oct 2019

Advances in translational genetics unlocked by Bio-Rad technologies to be presented at ASHG 2019

Scientists will present 24 abstracts and three talks, highlighting research driven in part by Bio-Rad Laboratories' Droplet Digital PCR and single-cell ATAC-Seq (scATAC-Seq) technologies, at the 2019 American Society of Human Genetics Annual Meeting in Houston, October 15-19.

15 Oct 2019

Biomarker News and Research

Further Reading

MRI contrast agent enables early detection of liver disease

TDP-43 study could speed up the diagnosis and treatment of ALS

New method helps assess the health of human hair follicles

Brain function changes could help diagnose and manage depression

First effective noninvasive method for diagnosing early-stage liver diseases

Researchers develop new test to detect nutrient deficiencies in harsh environments

Discovery of causal link between hydrogen sulfide and schizophrenia

Gait disorders can help predict future cognitive decline

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

Novel noninvasive imaging technique can provide information about thyroid disorders

Chronic kidney disease associated with increased risk of adverse cardiovascular outcomes

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Quanterix to release third quarter 2019 financial results and host conference call on November 6, 2019

Study: High levels of circ E7 is a positive prognostic marker in anal squamous cell carcinoma

Insilico Medicine presents experimentally validated model for drug discovery at NeurIPS 2019

Advances in translational genetics unlocked by Bio-Rad technologies to be presented at ASHG 2019

Study shows microbleeds after head injury signal danger to brain function

Genetic oscillator captures changes in gut microbiome growth patterns

Penn researchers to develop critical tool for imaging the brains of patients with Parkinson's

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