Central Nervous System News and Research

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CRP40 may have pathogenic role in schizophrenia

Gene expression of catecholamine-regulated protein 40 is dysregulated in people with schizophrenia, study findings show.

7 Dec 2012

Ultrasound applied to fingertips can stimulate sensory pathways leading to the brain

A century after the world's first ultrasonic detection device - invented in response to the sinking of the Titanic -Virginia Tech Carilion Research Institute scientists have provided the first neurophysiological evidence for something that researchers have long suspected: ultrasound applied to the periphery, such as the fingertips, can stimulate different sensory pathways leading to the brain.

7 Dec 2012

New genetic process could provide novel target for treatment of neurodevelopmental disorders

Researchers at the Douglas Mental Health University Institute, have discovered a new genetic process that could one day provide a novel target for the treatment of neurodevelopmental disorders, such as intellectual disability and autism.

7 Dec 2012

Study reveals dual role for Norrin/Frizzled-4 protein pair

Working with mice, Johns Hopkins researchers have shed light on the activity of a protein pair found in cells that form the walls of blood vessels in the brain and retina, experiments that could lead to therapeutic control of the blood-brain barrier and of blood vessel growth in the eye.

7 Dec 2012

Naurex reports positive results from GLYX-13 Phase IIa trial on depression

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today reported positive results from a Phase IIa clinical trial of its lead antidepressant compound, GLYX-13.

6 Dec 2012

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter dopamine (known as dopaminergic neurons). One of the primary goals in Parkinson's disease research is to develop a replacement for dopaminergic neurons.

4 Dec 2012

Pressure Right effectively reduces postdischarge nausea and vomiting

In its December 2012 issue, the Outpatient Surgery Magazine's product news section introduces Pressure Right, the longer-acting perioperative, (Rx) antiemetic prophylaxis medical device to its readers.

30 Nov 2012

ArmaGen closes $17M Series A financing

ArmaGen Technologies, Inc. today announced the closing of a $17 million Series A financing to support the development of brain-penetrating recombinant protein therapeutics.

29 Nov 2012

Child Neurology Society honors LSUHSC professor with 2012 Hower Award

The Child Neurology Society presented Ann Henderson Tilton, MD, Clinical Professor of Neurology at LSU Health Sciences Center New Orleans, with the 2012 Hower Award at the 41st Annual CNS Meeting in November.

29 Nov 2012

UCB to sponsor key sets of VIMPAT C-V data at 66th American Epilepsy Society annual meeting

UCB, a global biopharmaceutical company focusing on CNS and immunology treatment and research, is sponsoring key sets of VIMPAT® (lacosamide) C-V data at the 66th Annual Meeting of the American Epilepsy Society (AES) in San Diego, Calif., November 30 - December 4.

29 Nov 2012

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

28 Nov 2012

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

A new substance class for the treatment of multiple sclerosis and other neurodegenerative diseases now promises increased efficacy paired with fewer side effects. To achieve this, a team of scientists under the leadership of Prof. Gunter Fischer and Dr. Frank Striggow have combined two already approved pharmaceutical substances with each other using a chemical linker structure.

27 Nov 2012

Weight loss and quality of sleep: an interview with Kerry Stewart

In our particular study we used a survey which consisted of 50 different questions which get at different aspects of sleep health. It was a patient self-report.

26 Nov 2012

Study confirms high biocompatibility of polymeric materials with brain tissue

Professor José Miguel Soria, a member of the Institute of Biomedical Sciences, Universidad CEU Cardenal Herrera, has co-directed with Professor Manuel Monleón of the Universitat Politècnica de València a study on the compatibility of polymeric biomaterials in the brain and its effectiveness to favour neuroregeneration in areas with some kind of damage or brain injury.

26 Nov 2012

People with Parkinson's benefit from exercise programs on stationary bicycles

People with Parkinson's disease benefit from exercise programs on stationary bicycles, with the greatest effect for those who pedal faster, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Alcohol exposure during fetal development alters brain structure and metabolism in children

Children exposed to alcohol during fetal development exhibit changes in brain structure and metabolism that are visible using various imaging techniques, according to a new study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

26 Nov 2012

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

Lymphopenia is when you lack the T cells of your immune system. T cells are very important for controlling infection. Probably the most known cause of lymphopenia is HIV.

23 Nov 2012

IRCM researchers discover a nerve cell's internal clock

A team of IRCM researchers, led by Dr. Fr-d-ric Charron, recently uncovered a nerve cell's internal clock, used during embryonic development.

22 Nov 2012

Yawning could be linked to fetal development

The 4D scans of 15 healthy fetuses, by Durham and Lancaster Universities, also suggest that yawning is a developmental process which could potentially give doctors another index of a fetus' health.

22 Nov 2012

Australian TGA approves Genzyme’s AUBAGIO to treat relapsing forms of multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration (TGA) has approved AUBAGIO (teriflunomide) 14 mg as a new once-daily, oral treatment indicated for patients with relapsing forms of multiple sclerosis (MS).

21 Nov 2012

Central Nervous System News and Research

CRP40 may have pathogenic role in schizophrenia

Ultrasound applied to fingertips can stimulate sensory pathways leading to the brain

New genetic process could provide novel target for treatment of neurodevelopmental disorders

Study reveals dual role for Norrin/Frizzled-4 protein pair

Naurex reports positive results from GLYX-13 Phase IIa trial on depression

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Pressure Right effectively reduces postdischarge nausea and vomiting

ArmaGen closes $17M Series A financing

Child Neurology Society honors LSUHSC professor with 2012 Hower Award

UCB to sponsor key sets of VIMPAT C-V data at 66th American Epilepsy Society annual meeting

High-resolution real-time images show how nerves may be damaged during earliest stages of MS

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

Weight loss and quality of sleep: an interview with Kerry Stewart

Study confirms high biocompatibility of polymeric materials with brain tissue

People with Parkinson's benefit from exercise programs on stationary bicycles

Alcohol exposure during fetal development alters brain structure and metabolism in children

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

IRCM researchers discover a nerve cell's internal clock

Yawning could be linked to fetal development

Australian TGA approves Genzyme’s AUBAGIO to treat relapsing forms of multiple sclerosis

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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