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Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

While research has identified hundreds of genes required for normal memory formation, genes that suppress memory are of special interest because they offer insights into how the brain prioritizes and manages all of the information, including memories, that it takes in every day.

18 Apr 2016

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

A multi-institutional study led by a Massachusetts General Hospital investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, sometimes life-threatening adverse reaction to the most commonly prescribed medication. The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

16 Apr 2016

Scientists identify human protein that weakens immune response to HIV, other viruses

Scientists at the University of North Carolina School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have identified a human (host) protein that weakens the immune response to HIV and other viruses. The findings, published today in Cell Host & Microbe, have important implications for improving HIV antiviral therapies, creating effective viral vaccines, and advance a new approach to treat cancer.

16 Apr 2016

Low-carbohydrate diet helps reduce growth of glioblastoma tumor cells in mouse models

University of Florida Health researchers have slowed a notoriously aggressive type of brain tumor in mouse models by using a low-carbohydrate diet.

16 Apr 2016

Mouse model offers insight into molecular, neurological basis of stuttering

Mice that vocalize in a repetitive, halting pattern similar to human stuttering may provide insight into a condition that has perplexed scientists for centuries, according to a new study by researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health.

16 Apr 2016

Improving body clock could protect against metabolic syndrome

Essential biological processes are managed by an internal timer or body clock. When the body clock gets out of whack, conditions such as metabolic syndrome can occur.

15 Apr 2016

High dosages of antihistamines have dulling effect on genes associated with post-exercise recovery

After vigorous exercise, some 3,000 genes go to work to aid recovery by boosting muscles and blood vessels, but in the presence of high doses of antihistamines almost 27 percent of the gene response is blunted, according to University of Oregon researchers.

15 Apr 2016

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help protect against fibrotic damage in patients with systemic sclerosis, particularly in those who develop interstitial lung diseases (ILD), its deadliest complication.

15 Apr 2016

New research in SIV-exposed monkeys provides insights for development of HIV prevention strategies

New research in monkeys exposed to SIV, the monkey equivalent of HIV, suggests that the virus spreads rapidly in the body and triggers early host responses that suppress antiviral immunity, thus promoting viral replication.

15 Apr 2016

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects.

15 Apr 2016

Patients with genotype 1 chronic HCV infection achieve high SVR rates with VIEKIRAX + EXVIERA

AbbVie, a global biopharmaceutical company, today announced data showing that patients with genotype 1 (GT1) chronic hepatitis C virus (HCV) infection who received the recommended regimen of VIEKIRAX (ombitasvir/paritaprevir/ritonavir tablets) + EXVIERA (dasabuvir tablets), with or without ribavirin (RBV), achieved high sustained virologic response rates at 48 weeks post-treatment (SVR48), regardless of the presence of baseline resistance-associated variants (RAVs).

15 Apr 2016

PITRM1 protein may be involved in development of Alzheimer's disease

University of Bergen researchers have found a protein that could hold the key to understanding how Alzheimer's disease develops.

14 Apr 2016

Researchers identify protein that helps cancer cells to spread

Aggressive cancer cells spread from a tumour to another part of the body through the blood vessel. To be able get in and out of the blood vessel, the cancer cell needs to penetrate tissue. Researchers from The University of Bergen have discovered a protein that the cancer cell uses like scissors to cut up tissue, so it can spread from a tumour to a new organ.

13 Apr 2016

Scientists reveal mechanism involved in regulation of lymphangiogenesis

After an injury to tissues, such as in organ transplantation, the body grows new lymphatic vessels in a process known as lymphangiogenesis. A new study in Nature Communications reveals a mechanism involved in the regulation of this process, specifically in corneal transplants and infectious eye disease.

13 Apr 2016

Study reveals TRPV2 protein as new target for chronic pain, cancer treatments

In a recent paper published in Nature Communications, a group of Case Western University School of Medicine researchers presented their discovery of the full-length structure of a protein named Transient Receptor Potential Vanilloid subtype 2 (TRPV2).

13 Apr 2016

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Catherine Aaron and Gabrielle Beaudry were 17 when they knocked on the door of the laboratory of Alex Parker, a neuroscience researcher at the University of Montreal Hospital Research Centre. While students at Collège Jean-de-Brébeuf in Montreal, they were looking for a mentor for an after-school research project. Two and half years later, the results of this scientific adventure were published today in the Journal of Agricultural and Food Chemistry.

13 Apr 2016

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

Adding coffee to the diet of people with non-alcoholic fatty liver disease (NAFLD) could help reverse the condition, according to a new study conducted in mice presented at The International Liver Congress 2016 in Barcelona, Spain.

13 Apr 2016

Next generation analytical ultracentrifuge to be launched by Beckman Coulter at Analytica

Beckman Coulter Life Sciences is to launch the new Optima AUC at this year’s Analytica: 25th International Trade Fair.

From Beckman Coulter Life Sciences - Centrifugation 13 Apr 2016

High levels of COMP protein may lead to worse breast cancer prognosis

Research from Lund University in Sweden shows that the protein COMP, which mainly exists in cartilage, can also be found in breast cancer tumours in patients with a poor prognosis. Studies on mice also showed that COMP contributed to the development and metastasis of the breast cancer.

13 Apr 2016

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

The advent of targeted drugs for a specific type of breast cancer - HER2 positive - has dramatically improved survival rates for women with the disease. But a study led by researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center reveals low rates of use of a targeted drug among older women with early-stage breast cancer of this type, and even lower rates for older black women.

13 Apr 2016

G Protein News and Research

Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

Scientists identify human protein that weakens immune response to HIV, other viruses

Low-carbohydrate diet helps reduce growth of glioblastoma tumor cells in mouse models

Mouse model offers insight into molecular, neurological basis of stuttering

Improving body clock could protect against metabolic syndrome

High dosages of antihistamines have dulling effect on genes associated with post-exercise recovery

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

New research in SIV-exposed monkeys provides insights for development of HIV prevention strategies

UNIGE researchers identify PIGG gene that plays crucial role in recessive disease

Patients with genotype 1 chronic HCV infection achieve high SVR rates with VIEKIRAX + EXVIERA

PITRM1 protein may be involved in development of Alzheimer's disease

Researchers identify protein that helps cancer cells to spread

Scientists reveal mechanism involved in regulation of lymphangiogenesis

Study reveals TRPV2 protein as new target for chronic pain, cancer treatments

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

Next generation analytical ultracentrifuge to be launched by Beckman Coulter at Analytica

High levels of COMP protein may lead to worse breast cancer prognosis

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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