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Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

UBC researchers have identified three compounds that prevent COVID-19 infection in human cells, derived from natural sources including a B.C. sea sponge.

9 Jan 2023

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

Researchers performed a genomic assessment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant’s BA.1 subvariant transmission in England.

9 Jan 2023

Education about the role of genetics in eating behavior may help to alleviate weight stigma

Education about gene-by-environment interaction (G X E) causes of eating behaviors can have beneficial downstream effects on attitudes toward people with higher weight.

9 Jan 2023

Review focuses on the link between the pathogenesis and management of hepatocellular carcinoma

A new review was published in Genes & Cancer on December 13, 2022, entitled, "Pathogenesis to management of hepatocellular carcinoma."

9 Jan 2023

Clinically relevant biomarker strategies in drug development

In this interview, NewsMedical speaks with Dr. Justin Devine and Dr. Nicholas Woudberg about biomarkers, their importance for drug development as well as the potential they have when it comes to machine learning.

From Synexa Life Sciences 9 Jan 2023

New model for detecting and estimating pathogen variant dynamics and risk

A recent study posted to the medRxiv* preprint server developed a hierarchical modeling method to estimate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant fitness advantage and prevalence.

8 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Specific air pollutants linked to non-viral asthma attacks among children in urban communities

Moderate levels of two outdoor air pollutants, ozone and fine particulate matter, are associated with non-viral asthma attacks in children and adolescents who live in low-income urban areas, a study funded by the National Institutes of Health has found.

5 Jan 2023

Comparison of genetic codes reveals how humans and other mammals lost their hair

Orangutans, mice, and horses are covered with it, but humans aren't. Why we have significantly less body hair than most other mammals has long remained a mystery.

5 Jan 2023

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Multiple sclerosis patients do not have the same bacteria in their intestines as healthy people. There are also differences in the composition and function of the bacteria in the intestines of multiple sclerosis patients, depending on whether their illness is active, and whether they are in treatment.

5 Jan 2023

Genotype-first approach uncovers new relationships between genes and clinical conditions

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care.

5 Jan 2023

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Researchers uncovered a novel mechanism that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses (CoVs) use to exploit host antiviral immune system to facilitate their replication.

5 Jan 2023

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Researchers conducted a multicenter, cross-sectional seroprevalence study in emergency departments of five hospitals in North Rhine-Westphalia, Germany, between August and September 2022. They assessed point seroprevalence and neutralization activity against Wu01, BA.4/5, and BQ.1.1.

5 Jan 2023

New research extensively explores 12 distinctive aging traits

In a recent article published in Cell, researchers proposed that 12 distinctive traits of aging are all inter-related.

5 Jan 2023

Evolutionary advantage of jumping genes in a fungus discovered

A fungus that infects salamanders contains multiple copies of the same "jumping genes", scientists have discovered.

4 Jan 2023

Study assesses microbiome of male genital mucosa

A new study in the journal Microorganisms aimed to identify and analyze studies on the composition of the microbial community on different parts of the healthy and diseased male genital mucosa.

4 Jan 2023

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

4 Jan 2023

Genome News and Research

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

Researchers study the spatial distribution of SARS-CoV-2 Omicron BA.1 variant in England

Education about the role of genetics in eating behavior may help to alleviate weight stigma

Review focuses on the link between the pathogenesis and management of hepatocellular carcinoma

Clinically relevant biomarker strategies in drug development

New model for detecting and estimating pathogen variant dynamics and risk

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

Study details the “immunometabolic editing” mechanism of tumor evolution

Specific air pollutants linked to non-viral asthma attacks among children in urban communities

Comparison of genetic codes reveals how humans and other mammals lost their hair

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Genotype-first approach uncovers new relationships between genes and clinical conditions

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

New research extensively explores 12 distinctive aging traits

Evolutionary advantage of jumping genes in a fungus discovered

Study assesses microbiome of male genital mucosa

Recently discovered protein holds potential for the development of new tests for infectious diseases

New type of CRISPR gene scissors discovered

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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