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C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

C2N Diagnostics and AbbVie today announced that the U.S. Food and Drug Administration has granted their investigational recombinant humanized anti-tau antibody, C2N-8E12 (ABBV-8E12), an orphan drug designation for the treatment of progressive supranuclear palsy (PSP).

17 Jul 2015

$New study shows cannabinoid cannabidiol can help heal bone fractures$

New study shows cannabinoid cannabidiol can help heal bone fractures

Cannabis -- marijuana, hashish -- was used as a go-to medical remedy by societies around the world for centuries. But the therapeutic use of marijuana was banned in most countries in the 1930s and '40s due to a growing awareness of the dangers of addiction. The significant medical benefits of marijuana in alleviating symptoms of such diseases as Parkinson's, cancer, and multiple sclerosis have only recently been reinvestigated.

17 Jul 2015

Transcranial magnetic stimulation holds promise for tinnitus patients

In the largest U.S. clinical trial of its kind funded by the Veterans Affairs Rehabilitation Research and Development Service, researchers at the VA Portland Medical Center and Oregon Health & Science University found that transcranial magnetic stimulation significantly improved tinnitus symptoms for more than half of study participants.

17 Jul 2015

Kessler Foundation, University of Bordeaux team up to study emotional processing deficits in MS people

Kessler Foundation received $65,500 as part of a two-year $140,000 grant from the ARSEP Foundation of France to the University of Bordeaux, to launch a collaborative study of emotional processing deficits in people with multiple sclerosis (MS). Helen Genova, Ph.D., and Jean Lengenfelder, Ph.D., of Kessler Foundation and Bruno Brochet, M.D., Ph.D., of the University of Bordeaux are the principal investigators.

17 Jul 2015

Psychosocial factors linked to pain in multiple sclerosis

Psychosocial factors are important and potentially modifiable determinants of persistent pain in patients with multiple sclerosis who are taking pain medication, research shows.

16 Jul 2015

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

A study led by Shoukhrat Mitalipov, Ph.D., and Hong Ma, M.D., Ph.D., at the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University and the Oregon National Primate Research Center has revealed the first critical step in developing novel gene and stem cell therapy treatments for patients with mitochondrial disease.

16 Jul 2015

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Researchers recommend performing echocardiography at rest and during exercise to screen for pulmonary arterial hypertension in patients with systemic sclerosis.

15 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

Following restrictive sun exposure advice may be harmful to health

Following restrictive sun exposure advice in countries with low solar intensity like Canada might in fact be harmful to your health, says the co-author of a new study on sunlight and vitamin D.

14 Jul 2015

Hiroshima University researchers reveal molecular mechanisms involved in neuropathic pain

A research group from Hiroshima University demonstrated that the downregulation of spinal astrocyte connexin43 (Cx43) expression causes sustained neuropathic pain following peripheral nerve injury. Controlling the Cx43 expression using pharmacological approaches or gene therapy might serve as novel therapeutic strategies ameliorate neurological disorders in general and neuropathic pain in particular.

14 Jul 2015

Study analyzes attitudes and practices of general physicians in different vaccination scenarios

At population level, vaccines contribute to reducing mortality associated with infectious diseases such as measles, diphtheria, tetanus, hepatitis B or bacterial meningitis.

9 Jul 2015

Diabetes and high blood sugar impose negative effect on cognitive, decision-making skills

MINNEAPOLIS - In just two years, people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain, which was associated with lower scores on tests of cognition skills and their ability to perform their daily activities, according to a new study published in the July 8, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jul 2015

International consensus panel reviews new diagnostic criteria for neuromyelitis optica spectrum disorder

New diagnostic criteria were introduced this week for neuromyelitis optica, now called neuromyelitis optica spectrum disorder, which is an inflammatory disease of the central nervous system that is sometimes mistaken for multiple sclerosis.

9 Jul 2015

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer's disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.

8 Jul 2015

Decreased connectivity between network-specific brain regions linked to cognitive deficit in MS

An estimated 2.3 million individuals are living with multiple sclerosis (MS) worldwide. Approximately half of all individuals with MS experience changes in cognition such as impaired concentration, attention, memory, and judgment. The underlying brain basis for these deleterious effects has been largely elusive.

8 Jul 2015

Chromosomal abnormalities in embryos created for IVF can be predicted at earliest stage of human development

Scientists at Oregon Health & Science University, Stanford University, University of Valencia and IGENOMIX have discovered that chromosomal abnormalities in human embryos created for in vitro fertilization, or IVF, can be predicted within the first 30 hours of development at the cell-1 stage which results from the union of a female egg and male sperm.

8 Jul 2015

UC Davis scientists identify significant driver of neuropathic pain

Scientists at the University of California, Davis, have identified a key mechanism in neuropathic pain. The discovery could eventually benefit millions of patients with chronic pain from trauma, diabetes, shingles, multiple sclerosis or other conditions that cause nerve damage.

8 Jul 2015

Bacterial biofilms play role in development of systemic lupus erythematosus

Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body it was designed to defend. But just why the immune system begins its misdirected assault has remained a mystery.

7 Jul 2015

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Mohamed Boutjdir, PhD, professor of medicine, cell biology, and physiology and pharmacology at SUNY Downstate Medical Center, has led a study with international collaborators identifying the mechanism by which patients with various autoimmune and connective tissue disorders may be at risk for life-threatening cardiac events if they take certain anti-histamine or anti-depressant medications.

7 Jul 2015

Sclerosis News and Research

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

New study shows cannabinoid cannabidiol can help heal bone fractures

Transcranial magnetic stimulation holds promise for tinnitus patients

Kessler Foundation, University of Bordeaux team up to study emotional processing deficits in MS people

Psychosocial factors linked to pain in multiple sclerosis

Research breakthrough opens door to a world of regenerative medicine for treating mitochondrial disease

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

Following restrictive sun exposure advice may be harmful to health

Hiroshima University researchers reveal molecular mechanisms involved in neuropathic pain

Study analyzes attitudes and practices of general physicians in different vaccination scenarios

Diabetes and high blood sugar impose negative effect on cognitive, decision-making skills

International consensus panel reviews new diagnostic criteria for neuromyelitis optica spectrum disorder

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Decreased connectivity between network-specific brain regions linked to cognitive deficit in MS

Chromosomal abnormalities in embryos created for IVF can be predicted at earliest stage of human development

UC Davis scientists identify significant driver of neuropathic pain

Bacterial biofilms play role in development of systemic lupus erythematosus

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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