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Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

First limbal stem cell transplant performed in Ireland

On Tuesday 7th June 2016, the first Limbal Stem Cell transplant in Ireland was performed by Mr. William Power, Consultant Ophthalmologist at the Royal Victoria Eye and Ear Hospital in Dublin.

10 Jun 2016

New effort in biomedical engineering may improve heart repair

Jianyi "Jay" Zhang, M.D., Ph.D., brought his biomedical engineering expertise to the University of Alabama at Birmingham to fix hearts.

9 Jun 2016

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say.

9 Jun 2016

Two autologous stem-cell transplants improve survival of children with high-risk neuroblastoma

Children with high-risk neuroblastoma whose treatment included two autologous stem-cell transplants were more likely to be free of cancer three years later than patients who underwent a single transplant, a Phase 3 clinical trial has found.

7 Jun 2016

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Harvard Stem Cell Institute scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

7 Jun 2016

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.

7 Jun 2016

Human stem cells restore motor function in chronic stroke patients

Injecting modified, human, adult stem cells directly into the brains of chronic stroke patients proved not only safe but effective in restoring motor function, according to the findings of a small clinical trial led by Stanford University School of Medicine investigators.

7 Jun 2016

Combination immunotherapy may be better than one to combat metastatic melanoma

A new metastatic melanoma study suggests that a combination of two immunotherapies may be better than one.

7 Jun 2016

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

While several clinical trials have demonstrated that maintenance therapy with lenalidomide reduces the risk of disease progression in patients with multiple myeloma, there have been no definitive results regarding overall survival.

6 Jun 2016

Clinical study explores effect of iron supplements in reducing hospitalisation in heart failure patients

A clinical study - known as IRONMAN - will determine if iron supplement injections could ease the disabling symptoms of heart failure. The trial was officially launched today at the British Cardiovascular Society Conference in Manchester.

6 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

Retroviral replicating vector can extend lives of brain cancer patients

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with recurrent glioblastoma, the most common and aggressive form of brain cancer, by successfully demonstrating a modified virus that can extend the lives of patients with the disease.

2 Jun 2016

$CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory$

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

A two-year, multi-center clinical study with 167 patients with class III-IV refractory angina randomized to low and high dose CD34+ cells or placebo has revealed that patients who received either a high or low dose of CD34 -- a member of a family of proteins that have an impact on vascular-associated tissue -- cells had a significant reduction in angina frequency over patients who received placebo.

2 Jun 2016

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

On Friday, May 27, the U.S. Food and Drug Administration granted accelerated approval for Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

1 Jun 2016

New research in mice provides better understanding of how HD begins and develops

Mice transplanted with cells grown from a patient suffering from Huntington's disease (HD) develop the clinical features and brain pathology of that patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.

1 Jun 2016

Combining VCA with organ transplants improves patient outcomes

Simultaneous transplantation of a "composite" skull and scalp flap plus a kidney and pancreas—all from the same donor—provided excellent outcomes for a patient with a non-healing scalp defect and declining organ kidney and pancreas function, according to a report in the June issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 May 2016

Transplant News and Research

Carfilzomib therapy shows promise for pre-kidney transplant patients

First limbal stem cell transplant performed in Ireland

New effort in biomedical engineering may improve heart repair

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Two autologous stem-cell transplants improve survival of children with high-risk neuroblastoma

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Eculizumab drug provides new hope for kidney failure patients

Human stem cells restore motor function in chronic stroke patients

Combination immunotherapy may be better than one to combat metastatic melanoma

Maintenance lenalidomide treatment improves overall survival in multiple myeloma patients

Clinical study explores effect of iron supplements in reducing hospitalisation in heart failure patients

Scientists use new technique to repair fibrotic liver cells within the organ

Retroviral replicating vector can extend lives of brain cancer patients

CD34+ cell therapy improves angina frequency in no option patients with class III/IV angina refractory

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

New research in mice provides better understanding of how HD begins and develops

Combining VCA with organ transplants improves patient outcomes

UPMC study gives better understanding of cardiac arrhythmia following lung transplantation

New therapy may reduce stroke risk in severe sickle cell disease patients

Sylvester researchers test new KTE-C19 therapy for patients with aggressive non-Hodgkin's lymphoma

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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