Genetic News and Research

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New research explores role of genes, environment in post-natal depression

New research involving the University of York explores the interplay between genes and environment when determining whether a mother is at high or low risk for post-natal depression.

21 May 2011

New research contributes to basic biological understanding of how retinas develop

New research at UC Santa Barbara is contributing to the basic biological understanding of how retinas develop. The study is part of the campus's expanding vision research.

21 May 2011

Researchers uncover new details of unusual biological mechanism in brains of diverse species

Researchers at the University of California, San Diego School of Medicine have uncovered new details of an unusual biological mechanism in the brains of diverse species that not only helps regulate how their brains develop, but also how they function later in life. The discovery could lead to new biomarkers for specific neurological diseases in humans and, possibly, the development of drugs to cure them.

21 May 2011

Researchers develop cheap, reliable diagnostic test for HLRCC

Researchers at the University of Oxford have developed a cheap and reliable diagnostic test for a rare form of cancer. The test involves screening tumour samples for a particular molecular fingerprint unique to this type of cancer.

21 May 2011

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

No one knows the cause of most cases of Alzheimer's, Parkinson's and other neurodegenerative disorders. But researchers have found that certain factors are consistently associated with these debilitating conditions.

21 May 2011

Salk Institute researchers receive $5.5M Program Project Grant to analyze Williams syndrome

A multi-institutional team headed by Ursula Bellugi, professor and director of the Laboratory for Cognitive Neuroscience at the Salk Institute for Biological Studies, has been awarded a $5.5 million Program Project Grant by the National Institute of Child Health and Human Development to link social behavior to its underlying neurobiological and molecular genetic basis using Williams syndrome as a model.

21 May 2011

Berkeley Lab scientists reveal how protein-making machine bends without breaking

It sounds like hype from a late-night infomercial: It can twist and bend without breaking! And wait, there's more: It could someday help you fend off disease!

20 May 2011

Cholesterol drug may help treat mitochondrial diseases

A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.

20 May 2011

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine.

20 May 2011

Medical food resolves metabolic syndrome and cardiovascular risk factors

Researchers at the University of Florida and Metagenics Inc. today announced that a program consisting of a breakthrough medical food combined with a low-glycemic, Mediterranean-style diet is almost twice as effective as one of the best diets alone for lowering risk factors for cardiovascular disease, the leading cause of death in the U.S.

19 May 2011

Isis receives $5M milestone payment from GSK for initiating ISIS-TTRRx Phase 1 study

Isis Pharmaceuticals, Inc. announced today that it has earned a $5 million milestone payment from GlaxoSmithKline related to the initiation of a Phase 1 clinical study for ISIS-TTRRx.

19 May 2011

Modified vitamin A drug may help prevent age-related macular degeneration

Slowing down the aggregation or "clumping" of vitamin A in the eye may help prevent vision loss caused by macular degeneration, research from Columbia University Medical Center has found.

19 May 2011

Pitt researchers develop mouse model of major depressive disorder

Researchers at the University of Pittsburgh School of Medicine have developed a mouse model of major depressive disorder (MDD) that is based on a rare genetic mutation that appears to cause MDD in the majority of people who inherit it.

19 May 2011

Musculoskeletal pain, obesity and smoking linked to increased risk of back-related disability

Musculoskeletal pain, obesity, and smoking are among the factors associated with an increased risk of work disability due to low back disorders, reports a study in the May Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine.

19 May 2011

Stem cells from kidneys - World first from Australian scientists

According to Australian scientists, their latest stem cell research breakthrough will bring new treatments for a growing epidemic of chronic kidney disease. They are the first in the world to generate a type of stem cell from human kidney cells. The Melbourne scientists are hoping their discovery will have far-reaching effects in treating the disease.

19 May 2011

Two genes linked to worst cases of esophageal cancer

University of Rochester Medical Center researchers have pinpointed two genes that are amplified in the worst cases of esophageal cancer, providing data to support a new investigational treatment that targets those same genes.

19 May 2011

A new gene expression analysis technique on a single molecule sequencer

A new gene expression technique adapted for single molecule sequencing has enabled researchers at the RIKEN Omics Science Center (OSC) to accurately and quantitatively measure gene expression levels using only 100 nanograms of total RNA. The technique, which pairs RIKEN's Cap Analysis of Gene Expression (CAGE) protocol with the Helicos(R) Genetic Analysis System developed by Helicos BioSciences Corporation, opens the door to the detailed analysis of gene expression networks and rare cell populations. In recent years, next-generation DNA sequencers have produced an increasingly detailed picture of how genes are expressed at the molecular level. The transcriptional output of these genes - the RNA copies produced from DNA - has revealed a richness of complexity in transcript structure and function, providing insights into the molecular-level properties of cancers and other diseases.

19 May 2011

Mayo Clinic develops new screening procedure for Lynch syndrome detection

Mayo Clinic has developed a screening procedure that could dramatically increase testing for Lynch syndrome, a hereditary genetic disorder that raises cancer risk, particularly for colorectal cancer.

19 May 2011

Affymetrix launches new menu of multiple genomic microarray tools

Affymetrix, Inc. today announced the availability of multiple genomic microarray tools that will further enable scientists in the applied research field.

18 May 2011

UW C4C, Pharmigene execute licensing agreement for warfarin personalized medicine technology

The University of Washington Center for Commercialization and Pharmigene, a leader in advancing personalized medicine and reducing severe adverse reactions to drugs through genetic-based diagnostic solutions, today announced the execution of a licensing agreement between the parties.

18 May 2011

Genetic News and Research

New research explores role of genes, environment in post-natal depression

New research contributes to basic biological understanding of how retinas develop

Researchers uncover new details of unusual biological mechanism in brains of diverse species

Researchers develop cheap, reliable diagnostic test for HLRCC

Multiple toxic mechanisms link elevated iron, copper levels in the brain and extensive DNA damage

Salk Institute researchers receive $5.5M Program Project Grant to analyze Williams syndrome

Berkeley Lab scientists reveal how protein-making machine bends without breaking

Cholesterol drug may help treat mitochondrial diseases

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Medical food resolves metabolic syndrome and cardiovascular risk factors

Isis receives $5M milestone payment from GSK for initiating ISIS-TTRRx Phase 1 study

Modified vitamin A drug may help prevent age-related macular degeneration

Pitt researchers develop mouse model of major depressive disorder

Musculoskeletal pain, obesity and smoking linked to increased risk of back-related disability

Stem cells from kidneys - World first from Australian scientists

Two genes linked to worst cases of esophageal cancer

A new gene expression analysis technique on a single molecule sequencer

Mayo Clinic develops new screening procedure for Lynch syndrome detection

Affymetrix launches new menu of multiple genomic microarray tools

UW C4C, Pharmigene execute licensing agreement for warfarin personalized medicine technology

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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