Crystallography News and Research

RSS

Research sheds light on sun-induced DNA damage and repair

It is a well known fact that the sun’s ultraviolet rays can damage the skin. Now, a new study sheds light on what happens after DNA damage occurs, and how the body initiates repair.

15 Jul 2019

Structure of bacteria responsible for traveler's diarrhea deciphered

For the first time researchers have deciphered the near-atomic structure of filaments, called 'pili', that extend from the surface of bacteria that cause traveler's diarrhea.

10 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin Group 4 Jul 2019

Researchers shed light on bacterial fusion linked to Chlamydia’s pathogenicity

Most people know Chlamydia as the venereal disease that can cause infertility if left untreated. But for researchers studying the causative agent, Chlamydia trachomatis, it's a bacteria with intriguing properties.

24 Jun 2019

Researchers examine transport mechanism of bacterial membrane protein

An international research team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.

17 Jun 2019

Snapshot of chikungunya could help find new ways to prevent or treat viral arthritis

Chikungunya virus, once confined to the Eastern Hemisphere, has infected more than 1 million people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

4 Jun 2019

Researchers identify new mechanism for accessing damaged DNA

UV light damages the DNA of skin cells, which can lead to skin cancer.

31 May 2019

Overexpression of tumor suppressor gene may lead to B-cell lymphoma, study finds

Miguel Gallardo, researcher and coordinator of the H12O-CNIO Haematological Malignancies Clinical Research Unit headed by Joaquín Martínez at the Spanish National Cancer Research Centre, has participated in a study that revealed that hnRNP K overexpression may cause B-cell lymphomas, the most common types of blood cancer.

24 May 2019

Researchers map virulence factor of influenza A virus in real-time

The influenza A viruses, which have instigated deadly pandemics in the past, still remain a major global public health problem until today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to help them to infect host cells.

21 May 2019

Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

New approach could simplify identification of transport proteins in mycobacteria

A team headed by Dr. Claudia Jessen-Trefzer of the University of Freiburg's Institute for Pharmaceuticals Sciences has for the first time identified a transport protein in mycobacteria which is responsible for the uptake of the nutrient L-arabinofuranose.

30 Apr 2019

Scientists develop maps of two melatonin receptors vital for sleep, other biological processes

An international team of researchers used an X-ray laser at the Department of Energy’s SLAC National Accelerator Laboratory to create the first detailed maps of two melatonin receptors that tell our bodies when to go to sleep or wake up and guide other biological processes.

26 Apr 2019

Prokaryotic transport protein transports both left-handed and right-handed aspartate efficiently

Many biomolecules come in two versions that are each other's mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins, and uptake mechanisms were thought to share this preference.

26 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Scientists identify promising small molecules that curb errant proteins of AL amyloidosis

Scientists at Scripps Research have identified a group of small molecules that prevent structural changes to proteins that are at the root of AL amyloidosis, a progressive and often fatal disease.

12 Apr 2019

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

At the 60th Experimental Nuclear Magnetic Resonance Conference (ENC, www.enc-conference.org ), Bruker announced today a breakthrough in ultra-high field high-resolution NMR spectroscopy applied to structural biology and the study of functional intrinsically disordered proteins.

From Bruker BioSpin Group 10 Apr 2019

Science of Chocolate series of workshops aims to promote interest in science

This project has been coordinated by the Scientific Communication Unit of the Universitat Rovira i Virgili and the Catalan Chemical Research Institute.

10 Apr 2019

New discovery may explain low testosterone levels in men with diabetes

Scientists have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications.

28 Mar 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019

Biophysicists visualize atomic-level dynamics of largest protein-degrading machine

Protein dynamics are essential for their functions. Protein nanomachines made of multiple protein molecules are highly dynamics during their actions on their functional targets, sometime called substrates.

26 Feb 2019