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Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

Healthy diet can be key to preventing age-related macular degeneration

There is no permanent cure for age-related macular degeneration, the leading cause of vision loss in adults ages 50 and older affecting about 10 million Americans.

10 Apr 2018

Popular e-cigarette flavors produce different levels of toxins

The flavor of an e-cigarette may affect more than a consumer's taste buds, according to Penn State researchers who say the chemicals that make up different flavors also produce different levels of free radicals, toxins often associated with cancer and other diseases.

9 Apr 2018

Free Radical Formation in Electronic Cigarette Aerosols

An interview with Prof. John Richie, describing his presentation at Pittcon 2018 on free radical formation in electronic cigarette aerosols.

From Pittcon 5 Apr 2018

High levels of humanin protein found in placenta of women who delivered low-birthweight babies

For the first time, UCLA scientists have discovered higher levels of a protein called humanin in the placenta tissue of women who give birth to severely underweight infants.

28 Mar 2018

NIH researchers explore genetic clocks to understand role of aging in neurodegeneration

To understand the link between aging and neurodegenerative disorders such as Alzheimer's disease, NIH scientists compared the genetic clocks that tick during the lives of normal and mutant flies.

14 Mar 2018

Golgi stress signaling pathway found in cells with Huntington’s disease

Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants.

8 Mar 2018

Wine polyphenols may be good for oral health

Sipping wine is good for your colon and heart, possibly because of the beverage's abundant and structurally diverse polyphenols. Now researchers report in ACS' Journal of Agricultural and Food Chemistry that wine polyphenols might also be good for your oral health.

21 Feb 2018

Cervical tumors may be vulnerable to therapies that attack cancer's fuel supply, study shows

Cancer therapies have improved -- in some cases dramatically -- over the past two decades, but treatment for cervical cancer has remained largely unchanged. All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one-third of patients with cervical cancer that has spread beyond the cervix but not outside the pelvis.

15 Feb 2018

Microbubbles increase radiotherapy success against breast cancer

A new study found that injecting microbubbles filled with oxygen into breast cancer tumors makes them three times more sensitive to radiotherapy.

1 Feb 2018

Oxygen-filled microbubbles make breast tumors more sensitive to radiation therapy

Injecting breast cancer with oxygen-filled microbubbles makes tumors three-times more sensitive to radiation therapy and improves survival in animal models of the disease.

30 Jan 2018

Vitamin deficiency prevents proliferation of cancer stem cells

DPI effectively switches off the cancer stem cells, preventing their proliferation. "It's extraordinary; the cells just sit there as if in a state of suspended animation" explains Professor Michael Lisanti, Chair of Translational Medicine and lead investigator.

30 Jan 2018

Phototherapeutic technology shows potential as anti-cancer weapon

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy - which is limited to the skin and areas accessible with an endoscope - this technique can target and attack cancer cells that have spread deep inside the body, according to researchers at Washington University School of Medicine in St. Louis.

25 Jan 2018

Fluorescence imaging can track vitamin C in the body

Vitamin C is best known as a nutrient. In high enough doses, however, vitamin C also shows potential against many cancers, according to recent studies. To successfully develop vitamin C (chemically named ascorbic acid) as a medication, it is crucial to probe its concentration in the body, thus ensuring safe and effective doses.

24 Jan 2018

Enzyme inhibitor and chemotherapy combination regresses glioblastoma

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.

24 Jan 2018

Mitochondrial impairment may actually protect the brain in Parkinson's disease, study shows

A Norwegian study shows that impairment in mitochondria may actually protect the brain in Parkinson's disease.

15 Jan 2018

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It's financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.

5 Jan 2018