Inflammatory Disease News and Research

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Yale researchers use arthritis medication to treat patient with disfiguring sarcoidosis

An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a chronic disease that can affect multiple organs, with a drug approved for rheumatoid arthritis.

26 Dec 2018

A promising, effective vaccine for common respiratory disease

Skin vaccination using a microneedle patch that contains the inactivated respiratory syncytial virus (RSV) and a compound that stimulates immune responses to the virus has been found to enhance protection against this serious disease and reduce inflammation in the body after exposure to the virus, according to a study led by Georgia State University.

18 Dec 2018

DFG establishes nine new Research Units and one new Clinical Research Unit

The Deutsche Forschungsgemeinschaft is establishing nine new Research Units and one new Clinical Research Unit.

17 Dec 2018

Study: People living near oil and gas wells show early signs of cardiovascular disease

Researchers at the Colorado School of Public Health have found a possible connection between the intensity of oil and gas exploration in an area and early indicators of cardiovascular disease among nearby residents.

11 Dec 2018

Discovery could be used to prevent viral infection and autoimmunity

Researchers have discovered that chemical changes to mRNA regulate the production of interferon beta, and hope to exploit this in new treatments.

27 Nov 2018

Researchers identify powerful inhibitor of epigenetic factors that promote acute myeloid leukemia

Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit the dysregulated proteins.

27 Nov 2018

Gum disease linked with diabetes

Gum disease and diabetes are chronic conditions that increase with age. The link between the two diseases goes both ways. It is thought that inflammation in the body is the connection- in fact, gum disease is the most common inflammatory disease.

14 Nov 2018

Beneficial gut microbes metabolize high-fiber diet to improve heart health in mouse model

Diets rich in fiber have long been associated with an array of positive outcomes, chief among them healthy hearts and arteries protected from the ravages of atherosclerosis, the accumulation of fatty plaques linked to heart attacks and strokes.

13 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

B cell accumulation triggers nervous system damage in MS

B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple Sclerosis (MS) they can damage nerve tissue.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Researchers discover how protein pair regulates cellular calcium signals

All mammalian cells need a ready supply of calcium ions to execute functions as diverse as neurotransmission, muscle contraction, hormone release, or immune responses. So fundamental is this requirement that cells protect themselves from disaster by storing calcium in a network of intracellular cisterns called the endoplasmic reticulum, or ER.

31 Oct 2018

Meta-analysis reveals effective treatment options for urticarial vasculitis

What treatments are available for patients with the rare inflammatory disease known as urticarial vasculitis? How effective are these treatments? Researchers from Charité - Universitätsmedizin Berlin embarked on a systematic review and meta-analysis to address these questions.

30 Oct 2018

Atopic dermatitis found to be highly prevalent among adults in the U.S.

As many as 16.5 million adults in America suffer from a skin disease known as atopic dermatitis, an inflammatory disease that results in red, itchy skin.

30 Oct 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

Immune therapy may be potential treatment option for patients with hard-to-treat ankylosing spondylitis

Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis, a chronic inflammatory disease characterized by back pain and sacroiliac-joint damage, may have another treatment option in the biologic drug ixekizumab.

22 Oct 2018

Survey results highlight the need for better communication between patients and HCPs about bacterial vaginosis

According to an online survey, although healthcare providers report sharing crucial information on bacterial vaginosis with patients, the associated risks of the condition remain a mystery to many women, indicating a significant disconnect.

16 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018