Kidney Transplant News and Research

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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

Powerful immune molecule silences barrel to protect transplanted organs from rejection

A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.

5 Feb 2019

New research increases options for kidney transplant patients with blood type B

Kidney transplant recipients are now benefiting from donor organs that do not match their blood type but are compatible and just as safe, according to a Vanderbilt University Medical Center study in the Journal of the American College of Surgeons.

1 Feb 2019

Excessive suppression of GSK3 enzyme can trigger renal failure, finds study

Scientists have identified an enzyme that is a "master regulator" of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals.

24 Jan 2019

Younger patients receiving kidney transplant more likely to live longer, shows data

The standard work-up of kidney transplant candidates is complex and includes many medical tests in part because most CKD patients are older and suffer from many comorbidities, for example, diabetes, hypertension or heart disease.

23 Jan 2019

King's researcher and team set up 'Harmonies of Hope' choir for kidney transplant children

A research fellow from King's College London and transplant surgeon in training from Guy's and Evelina Children's Hospital, Mr Pankaj Chandak, has set up a choir for children who have received a kidney transplant.

7 Jan 2019

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

A new study has found that genes cause about 1 in 10 cases of chronic kidney disease in adults, and identifying the responsible gene has a direct impact on treatment for most of these patients.

26 Dec 2018

New data demonstrates clinical utility of AlloSure in repeat kidney transplant recipients

CareDx, Inc., a leading molecular diagnostics company focused on the discovery, development and commercialization of clinically differentiated, high-value diagnostic solutions for transplant patients, today announces the publication of data demonstrating the clinical utility of measuring AlloSure in repeat kidney transplant recipients in the American Journal of Transplantation.

21 Dec 2018

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

A study of more than 1.3 million Australians with diabetes has found that kidney failure is increasing in people with type 2 diabetes aged under 50 years, leading to reduced quality of life and placing growing demand on the country's kidney dialysis and transplantation services.

19 Dec 2018

Acutely injured deceased-donor kidneys are suitable for transplant, study suggests

Organ procurement teams are sometimes leery of accepting kidneys from deceased donors with acute kidney injury, fearing they will harm the recipients. However, a national study chaired by a Johns Hopkins kidney specialist suggests these fears may be unfounded.

7 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

New therapeutic drug monitoring service could benefit children with cancer

Children with cancer are to benefit nationally from a service which for the first time will allow doctors to personalize their treatment.

28 Nov 2018

Myriad biological, societal factors that impact CKD severity for children of African descent

Myriad biological and societal factors can impact the occurrence and accelerate progression of chronic kidney disease for children of African descent - including preterm birth, exposure to toxins during gestation and lower socioeconomic status - and can complicate these children's access to effective treatments, according to an invited commentary published in the November 2018 edition of American Journal of Kidney Diseases.

21 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Inequality issues persist even under new U.S. kidney transplant allocation system

The implementation of a new U.S. kidney transplant allocation system did not solve many of the inequities that low-income and minority kidney disease patients face, Drexel University College of Medicine researchers found in a new study published recently in the journal Clinical Transplantation.

18 Sep 2018

Previously unknown virus acts as 'driver' for interstitial nephropathy

An international research team led by Wolfgang Weninger, who has been Head of MedUni Vienna's Department of Dermatology since 1 September, has discovered a previously unknown virus that acts as a "driver" for certain kidney diseases (interstitial nephropathy).

14 Sep 2018

Kidney Transplant News and Research

Further Reading

Large-scale clinical trial begins to study liver transplantation between people with HIV

Powerful immune molecule silences barrel to protect transplanted organs from rejection

New research increases options for kidney transplant patients with blood type B

Excessive suppression of GSK3 enzyme can trigger renal failure, finds study

Younger patients receiving kidney transplant more likely to live longer, shows data

King's researcher and team set up 'Harmonies of Hope' choir for kidney transplant children

Genetic testing can help personalize diagnosis and treatment of kidney disease, study shows

New data demonstrates clinical utility of AlloSure in repeat kidney transplant recipients

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

Acutely injured deceased-donor kidneys are suitable for transplant, study suggests

Elevated hormone flags liver disease in mice with serious genomic disorder

New therapeutic drug monitoring service could benefit children with cancer

Myriad biological, societal factors that impact CKD severity for children of African descent

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Inequality issues persist even under new U.S. kidney transplant allocation system

Previously unknown virus acts as 'driver' for interstitial nephropathy

New LSU research aims to prevent kidney failure caused by type 2 diabetes

Innovative kidney matching process can improve success rates of kidney transplants

Innovative questionnaire reveals most common symptoms reported by people with kidney disease

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