Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Genetic analysis shows smoking and high BMI increase dementia risk, but education and exercise protect

Mendelian randomization of 400,000 participants reveals smoking, high BMI, and high cholesterol as major genetic risk factors for dementia, while longer education and physical activity reduce risks.

17 Oct 2024

Updated Food Compass 2.0 improves food health ratings using new diet data

Food Compass 2.0 refines the original nutrient profiling system by incorporating updated health data and ingredient assessments. This system offers more accurate scoring of foods and beverages, promoting healthier dietary choices globally.

13 Oct 2024

Understanding the surprising link between HDL cholesterol quality and Alzheimer's risk

Higher levels of HDL-C - known as the "good cholesterol" - have been shown to correlate with heightened risk for Alzheimer's disease.

12 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Researchers discover effective treatment strategy for lethal glioblastoma

Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy treatments, the two-year survival rate for GBM patients is less than 10%.

7 Oct 2024

US adults face worse midlife health compared to British counterparts

A study reveals poorer cardiometabolic health in middle-aged Americans compared to Brits, highlighting the impact of socioeconomic status on health outcomes.

7 Oct 2024

Ketogenic diet lowers mortality by 24% while maintaining heart health

Study confirms that adherence to a ketogenic diet reduces all-cause mortality risk by 24% without increasing cardiovascular mortality in a large US cohort. Findings support KD as a beneficial intervention for long-term health.

3 Oct 2024

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict metabolic syndrome across populations.

1 Oct 2024

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Targeted obesity programs reduce lipid-related heart disease risk in children

Researchers assess the lipid profiles of obese children and adolescents and their health implications.

24 Sep 2024

A week of intense cycling may burn abdominal fat without major weight loss, study finds

A week of extreme cycling significantly decreased visceral adiposity in middle-aged cyclists, emphasizing the role of exercise in body composition management.

23 Sep 2024

Childhood adversity linked to elevated health risks, differing by sex and stress

Researchers assess the heterogeneous effects of childhood adversity on disease biomarkers and health conditions in adulthood.

20 Sep 2024

Lipid metabolism plays a critical role in red blood cell recovery from acute anemia

Red blood cells are the most abundant cells in the body. It has long been known that when red blood cells break down or anemia occurs due to bleeding, the hormone erythropoietin (EPO) increases, leading to the proliferation of immature cells (erythroblasts) that eventually become red blood cells, thus restoring the red blood cell count.

20 Sep 2024

FIND Lp(a) machine learning model aims to transform cardiovascular disease screening

Today, the Family Heart Foundation®, a leading research and advocacy organization, announced the successful completion of the Flag, Identify, Network and Deliver™ “FIND Lp(a)” machine learning model – a first-of-its-kind offering being implemented in care delivery systems across the United States.

19 Sep 2024

Breakthrough metabolomic aging score that predicts mortality better than traditional methods

Researchers developed a metabolomic aging score using NMR biomarkers that predicts short-term mortality and disease risk more accurately than other aging metrics.

16 Sep 2024

High-pressure homogenization stabilizes paprika oleoresin

Paprika oleoresin (PO), extracted from chili peppers, is renowned for its vibrant color and beneficial health properties, such as antioxidant and anti-inflammatory effects. However, its lipophilic nature and sensitivity to factors like oxygen, heat, and light restrict its use in water-based foods. While previous approaches, including emulsions and liposomes, have aimed to improve PO's stability, the results have been limited. These persistent challenges underscore the need for new stabilization methods for PO.

14 Sep 2024

Significant global cardiovascular risk linked to high lipoprotein(a) levels

Review in The Lancet finds that one in five globally are at risk of contracting cardiovascular diseases, because they carry a genetic risk of high levels of a specific lipoprotein, which can be tested for and possibly treated.

12 Sep 2024

Endurance exercise transforms fat tissue and boosts metabolic health in adults with obesity

Regular endurance exercise significantly remodels abdominal subcutaneous fat in adults with obesity, enhancing its metabolic function and contributing to better cardiometabolic health.

11 Sep 2024