Mammalian Cells News and Research

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Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions.

30 Aug 2016

Kobe University researchers develop new technique for high-level genome editing operation

A team involving Kobe University researchers has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA.

26 Aug 2016

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

A research team headed by investigators at the Icahn School of Medicine at Mount Sinai has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell.

5 Aug 2016

Study shows continuous dehydration kills cells during dry preservation

A new finding in experiments studying the dry preservation of living cells -- a potentially revolutionary alternative to cryopreservation - has defined a clear limit where continuing dehydration kills cells.

17 Jul 2016

Knocking out genes in E. coli affects stiffness, integrity of bacterial envelope

An exhaustive look at how bacteria hold their ground and avoid getting pushed around by their environment shows how dozens of genes aid the essential job of protecting cells from popping when tensions run high.

17 Jun 2016

New mathematical model helps examine metabolism of breast epithelium

Researchers have built a model to investigate the metastasis of cancer by examining the metabolism of breast epithelial cells and look at the role of signaling. This research, published in PLOS Computational Biology, may contribute to the development of cell specific anti-cancer interventions.

8 Jun 2016

New player in calcium signalling pathways acts as molecular brake to Orai activation

Information flow in cells relies on calcium as a key agent in several signalling pathways. Calcium dependent signalling is crucial in nearly every aspect of life - muscle movement, immune reactions, nerve function, light sensing and many such processes.

28 May 2016

New real-time imaging technique holds great potential in shaping assisted reproduction procedures

Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have developed advanced microscopy technologies to monitor embryo development in real time, revealing how mammalian cells differentiate during the earliest stages of embryonic life.

23 May 2016

Distek launches BIOne benchtop scale single-use bioreactor system

From the company that has brought you 40 years of excellence in laboratory pharmaceutical instruments, Distek, Inc. is proud to introduce the BIOne Single-Use Bioreactor System.

20 May 2016

Major breakthrough in understanding impact of oxygen exposure on aging process

A study published in the US journal, Aging by the University of Surrey and University of Rochester has made an important breakthrough in understanding the impact of oxygen exposure on the aging process of mammal cells.

12 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

IPC PAS‘s chemical sensor can rapidly and effectively detect fungal infections

Fungal infections are a serious problem in modern health care. A critical factor in their successful treatment is time: the faster they are detected, the more effectively dangerous infections can be prevented.

28 Apr 2016

Scientists develop new strategy to combat wide range of viruses

Scientists and health officials are marshalling forces to fight Zika, the latest in a string of recent outbreaks. Many of these efforts target that virus specifically, but some researchers are looking for a broader approach. Now one team reports in ACS' journal Macromolecules a new strategy to fight a wide range of viruses that appears to be safe in vivo and could evade a virus's ability to develop resistance.

21 Apr 2016

DKFZ researchers develop new methods to study disease-relevant changes in production of oxidants

There are many false beliefs and myths about the role of oxidants and antioxidants in the human body. Traditionally, oxidants are presented as harmful and antioxidants as health-promoting. However, scientists have known for many years that endogenous oxidants are essential chemical messengers that help keep up the functions of the organism.

20 Apr 2016

New GHz-class NMR magnet and probe technologies introduced by Bruker at ENC 2016

At the 57th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker announced new GHz-class NMR magnet and probe technologies to enable expanding frontiers in structural biology, membrane protein and intrinsically disordered protein (IDP) research.

From Bruker BioSpin - NMR, EPR and Imaging 11 Apr 2016

High-throughput RNA interference screen identifies potential drug target against henipaviruses

The closely related Hendra and Nipah viruses (referred to jointly as henipaviruses) are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses, all members of the paramyxovirus family. Henipavirus outbreaks are on the rise, but little is known about them, partly because research has to be conducted under extreme level containment conditions.

28 Mar 2016

Automated techniques could dramatically accelerate antimicrobial discovery

The antimicrobial arsenal that we count on to save millions of lives each year is alarmingly thin--and these microbes are rapidly evolving resistance to our weapons. But help may be on the way: In a study posted in the AMB Express, researchers from the National Institute of Standards and Technology show that automated techniques commonly used to screen new drugs for mammalian cell toxicity could also dramatically speed up the challenging task of antimicrobial discovery.

17 Mar 2016