Metabolic Disease News and Research

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High prevalence and risks of heart failure warrant urgent action, say researchers

Up to 2% of adults in Europe, North America, and Israel likely have heart failure, and are at high risk of death and additional serious complications, suggest current estimates based on digital health records for 11 countries, and published online in the journal Heart.

14 Feb 2023

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Recently, scientists have reviewed the existing literature to elucidate the root cause of metabolic syndrome and type 2 diabetes.

10 Feb 2023

Metabolically unhealthy people may be at increased risk of obesity-related cancer

For up to 40 years, nearly 800,000 people from Sweden, Norway and Austria have been tracked based on how their BMI and metabolic health - that is, their blood pressure, blood glucose levels and blood fats - affect the risk of suffering from obesity-related cancers.

7 Feb 2023

Owlstone Medical Publishes Data on the Use of Exhaled Volatile Organic Compounds as Biomarkers for Liver Disease Detection

Owlstone Medical (“Owlstone”), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced the publication of a peer-reviewed study in the Journal of Clinical and Translational Hepatology, “Breath Biopsy to identify exhaled volatile organic compounds as biomarkers for liver cirrhosis detection”.

From Owlstone Medical Ltd 7 Feb 2023

Research offers hope for patients affected by rare, hereditary metabolic disease

Methylmalonic aciduria (MMA) is a metabolic disorder that affects approximately one in 90,000 newborns; both parents must carry a genetic predisposition to the disease.

26 Jan 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Exposure to blue-green algae toxin shown to wreak havoc on gut bacteria and cause liver damage

Exposure to a specific type of blue-green algae toxin known as cylindrospermopsin has shown to wreak havoc on gut bacteria and an increased probability of irritable bowel syndrome, inflammatory bowel disease, celiac disease, type 1 diabetes, obesity and inflammation of the liver – a precursor to liver cancer – according to a study led by the University of California, Irvine.

20 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Consistent exercise linked to beneficial epigenetic changes, twin-study shows

Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates.

6 Dec 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

A new paper published in JAMA Network Open discusses the relationship between caffeine consumption in pregnancy and the future growth of the offspring.

1 Nov 2022

In utero exposure to flame retardant results in altered brain development in newborn rats

A new study from North Carolina State University shows that exposure in utero to the flame retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats.

24 Oct 2022

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Two of the world's leading authorities on bariatric and metabolic surgery have issued new evidence-based clinical guidelines that among a slew of recommendations expand patient eligibility for weight-loss surgery and endorse metabolic surgery for patients with type 2 diabetes beginning at a body mass index (BMI) of 30, a measure of body fat based on a person's height and weight and one of several important screening criteria for surgery.

21 Oct 2022

Metabolic Disease News and Research

High prevalence and risks of heart failure warrant urgent action, say researchers

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Metabolically unhealthy people may be at increased risk of obesity-related cancer

Owlstone Medical Publishes Data on the Use of Exhaled Volatile Organic Compounds as Biomarkers for Liver Disease Detection

Research offers hope for patients affected by rare, hereditary metabolic disease

The relationship between metabolic disease and alternations in lipid homeostasis

Exposure to blue-green algae toxin shown to wreak havoc on gut bacteria and cause liver damage

Many genetic disorders respond well to specialized gene therapy

Consistent exercise linked to beneficial epigenetic changes, twin-study shows

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

Environmental toxicants contribute to obesity and metabolic disease

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

In utero exposure to flame retardant results in altered brain development in newborn rats

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Enhanced thermogenesis depends on the circadian clock of adipocytes, study reveals

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

Weight loss gadgets: They provide data to help consumers achieve diet goals, but it still won’t be easy

Exercise can favorably modify subcutaneous adipose tissue that can improve metabolic health

eBook: Integrated solutions for metabolic disease drug development eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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