Microscope News and Research

RSS

Brazilian tree compound offers hope for visceral leishmaniasis treatment

A compound derived from Nectandra leucantha, a tree native to southern Brazil (local names canela-seca or canela-branca), has the potential to be used to treat visceral leishmaniasis, a neglected tropical disease associated with poverty, malnutrition, poor housing and lack of basic sanitation.

7 Jan 2025

Study reveals major differences between human and mouse PD-1 in cancer research

Since its discovery in the 1990s, "programmed cell death protein 1," or PD-1, has been regarded as a leading target in cancer treatments.

3 Jan 2025

Oldest evidence of evolutionary arms race found in fossils

A new study led by researchers at the American Museum of Natural History presents the oldest known example in the fossil record of an evolutionary arms race.

3 Jan 2025

New immunotherapy shows long-term benefits in preventing squamous cell carcinoma

A new study by investigators from Mass General Brigham uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment.

2 Jan 2025

Study reveals how fatty liver disease leads to liver cancer

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide.

2 Jan 2025

Advancing Raman microscopy for high-resolution imaging of biological samples

Understanding the behavior of the molecules and cells that make up our bodies is critical for the advancement of medicine.

30 Dec 2024

The "Goldilocks" zone: A key to cellular adaptability and resilience

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

24 Dec 2024

Atom probe tomography reveals fluoride patterns in aging teeth

Teeth are essential for helping people break down the food they eat and are protected by enamel, which helps them withstand the large amount of stress they experience as people chew away. Unlike other materials in the body, enamel has no way to repair damage, which means that as we age, it risks becoming weaker with time.

20 Dec 2024

A novel approach to combatting prostate cancer

New research by a team of Indiana University School of Medicine scientists and their collaborators has uncovered a novel vulnerability in prostate cancer animal models that starves prostate tumors of critical nutrients and stunts their growth, which could lead to the development of new treatments for the deadly disease.

19 Dec 2024

Huntsman Cancer Institute joins innovative clinical trials program for blood cancers

Huntsman Cancer Institute at the University of Utah (the U) has joined other institutions in an innovative clinical trials program designed to match patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) with a clinical trial specifically designed for the genetic signature of their disease.

17 Dec 2024

Renowned neuroscientist reveals key insights into how brain circuits drive addictive behaviors

In a comprehensive Genomic Press Interview published today in Brain Medicine, renowned neuroscientist Dr. Peter Kalivas reveals crucial insights into how brain circuits drive addictive behaviors and discusses potential new drug targets for treating behavioral disorders.

17 Dec 2024

Novel drug holds promise for treating Duchenne muscular dystrophy

A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration.

16 Dec 2024

The risks of reversed chirality: Study highlights dangers of mirror organisms

The study on mirror bacteria highlights risks of immune evasion and ecological threats, calling for collaboration to ensure safe synthetic biology practices.

16 Dec 2024

DTI detects precancerous lesions in the pancreas

Precursor lesions of pancreatic cancer are very difficult to characterize with magnetic resonance imaging (MRI). But now, in a new study, researchers led by Noam Shemesh and Carlos Bilreiro – respectively head of the Preclinical MRI lab at Champalimaud Research and a doctor at the Champalimaud Clinical Centre's Radiology Department – have shown, for the first time, that a particular form of MRI, called Diffusion Tensor Imaging (DTI), is capable of robustly detecting pre-malignant lesions in the pancreas.

13 Dec 2024

Study uncovers brain mechanism behind empathetic responses

A specific brain mechanism modulates how animals respond empathetically to others' emotions. This is the latest finding from the research unit Genetics of Cognition, led by Francesco Papaleo, Principal Investigator at the Istituto Italiano di Tecnologia (IIT - Italian Institute of Technology) and affiliated with IRCCS Ospedale Policlinico San Martino in Genova.

12 Dec 2024

New study uncovers role of amino acid serine in preventing food poisoning

Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. It is sometimes caused by Clostridium perfringens, a pathogen widely found in soil and the intestinal tracts of animals.

12 Dec 2024

Caltech develops microrobots for precise drug delivery

In the future, delivering therapeutic drugs exactly where they are needed within the body could be the task of miniature robots. Not little metal humanoid or even bio-mimicking robots; think instead of tiny bubble-like spheres.

11 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

Reimagining axons with the pearls-on-a-string model

In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons -- the long, thin filaments radiating from nerve cells that transmit electrical signals from cell to cell – and propose a new model for understanding how information is transmitted in the brain.

6 Dec 2024

Fas-p53 pathway drives metabolic dysfunction and obesity-linked insulin resistance

Researchers unveil Fas-p53 axis as a key regulator in adipocyte metabolism, linking it to obesity and insulin sensitivity through energy expenditure and inflammation pathways.

3 Dec 2024