Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Testing for a common genetic variant may help reveal which patients face an increased risk of developing kidney damage following heart surgery. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, may help investigators develop therapeutic strategies to mitigate this damage.

3 Jun 2016

$Sostdc1 gene may play vital role in fracture healing process$

Sostdc1 gene may play vital role in fracture healing process

New identification of a gene involved in the fracture healing process could lead to the development of new therapeutic treatments for difficult-to-heal injuries.

2 Jun 2016

Combining VCA with organ transplants improves patient outcomes

Simultaneous transplantation of a "composite" skull and scalp flap plus a kidney and pancreas—all from the same donor—provided excellent outcomes for a patient with a non-healing scalp defect and declining organ kidney and pancreas function, according to a report in the June issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 May 2016

CKD status does not affect health status outcomes after AMI

Chronic kidney disease does not accentuate the decline in health status often experienced by patients after acute myocardial infarction, US study data show.

27 May 2016

Accumulation of gut bacterial metabolite may lead to serious health problems in CKD patients

In patients with chronic kidney disease (CKD), the accumulation of a gut bacterial metabolite that's normally excreted in urine may contribute to serious health problems. The findings come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

27 May 2016

Majority of young adults with abdominal obesity unaware of CKD risk

Many young adults with abdominal obesity exhibit a readily detectable risk factor for chronic kidney disease (CKD), yet the vast majority don't know they're at risk, according to a study of nationwide health data led by Albert Einstein College of Medicine researchers that was published online today in the journal PLOS ONE.

26 May 2016

Sodium excretion linked to CVD risk in chronic kidney disease

High levels of sodium excretion are associated with a significantly increased risk of cardiovascular disease in patients with chronic kidney disease (CKD), US study findings indicate.

26 May 2016

Study finds link between sodium intake and clinical CVD events in CKD patients

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

25 May 2016

Chloride switch controls critical step in basement membrane formation

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

24 May 2016

Study: One-third of patients hospitalised with heart failure do not return to work

One-third of patients hospitalised with heart failure for the first time have not returned to work one year later, reveals a study in nearly 12 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Rasmus Roerth, a physician at Copenhagen University Hospital in Copenhagen, Denmark.

23 May 2016

SeeKD targeted screening program helps early detection of CKD risk in Canadians

A screening program for chronic kidney disease (CKD) initiated in Canada has successfully identified a high proportion of individuals with risk factors for CKD as well as many with unrecognized CKD.

20 May 2016

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries.

20 May 2016

Simple sarcopenia screening method could easily diagnose severity of heart disease

Researchers from Kumamoto University in Japan have shown that a simple screening method could quickly and easily diagnose the severity of heart disease. The method was originally developed to diagnose sarcopenia, a disease that causes a loss of muscle mass and strength.

19 May 2016

Innovative research technique may help understand early stage kidney disease

UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

19 May 2016

UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

Electronic health records have the potential to reduce the incidence of medical errors, duplication of tests, and delays in treatment.

19 May 2016

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

They may be in small towns. They may only have a couple of surgeons. But for common operations, they may be safer and less expensive than their larger cousins, a new study finds.

18 May 2016

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

The motor protein Myo1c binds to Neph1, a protein crucial for ensuring effective filtration by the kidney, and serves as one mode of its cellular transport, according to findings by investigators at the Medical University of South Carolina and their collaborators reported in the May 16, 2016 issue of Molecular and Cellular Biology.

17 May 2016

Nephropathy News and Research

Further Reading

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Sostdc1 gene may play vital role in fracture healing process

Combining VCA with organ transplants improves patient outcomes

CKD status does not affect health status outcomes after AMI

Accumulation of gut bacterial metabolite may lead to serious health problems in CKD patients

Majority of young adults with abdominal obesity unaware of CKD risk

Sodium excretion linked to CVD risk in chronic kidney disease

Study finds link between sodium intake and clinical CVD events in CKD patients

Chloride switch controls critical step in basement membrane formation

Study: One-third of patients hospitalised with heart failure do not return to work

SeeKD targeted screening program helps early detection of CKD risk in Canadians

Combined public health intervention could help manage CKD in developing countries

Simple sarcopenia screening method could easily diagnose severity of heart disease

Innovative research technique may help understand early stage kidney disease

UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

University of Colorado Boulder combines Raman spectroscopy and nanoindentation for improved materials characterisation

Combination of two compounds found in red grapes, oranges could treat diseases

Genetic mutations may be key culprit behind ciliopathies, study shows

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