Small Molecules News and Research

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MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

The University of Texas MD Anderson Cancer Center and Jazz Pharmaceuticals plc today announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz's investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.

7 Nov 2023

New drug shows promise in killing cancer cells with genetic vulnerability

Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.

1 Nov 2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

30 Oct 2023

Virginia Tech researchers develop new drug design framework to fight COVID-19

As the COVID-19 pandemic scattered and isolated people, researchers across Virginia Tech connected for a data-driven collaboration seeking improved drugs to fight the disease and potentially many other illnesses.

19 Oct 2023

Study sheds light on how NAD+ levels decline with age in the ovaries, affecting fertility

A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause.

18 Oct 2023

Ensuring raw material quality in drug production and manufacturing

In this interview, Thermo Fisher Scientific discusses how to ensure the high quality of raw material in the drug production and manufacturing pipeline.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 12 Oct 2023

Drug Discovery 2023: A Conversation with Professor Janet Hemingway

We spoke to Professor Janet Hemingway, founding Director of iiCON and Professor of Tropical Medicine at Liverpool School of Tropical Medicine.

From ELRIG (UK) Ltd. 9 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Artificial life forms could be used in the future for diagnosing and treating diseases

Creating artificial life is a recurring theme in both science and popular literature, where it conjures images of creeping slime creatures with malevolent intentions or super-cute designer pets.

5 Oct 2023

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University.

4 Oct 2023

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

Researchers developed the ATRIVIEW® platform to screen for molecules that promote differentiation neural stem cells (NSCs).

4 Oct 2023

UNH research seeks to quantify health outcomes based on food access, fiber intake and gut microbiota

The U.S. obesity epidemic continues to have profound impacts on individuals’ health and socioeconomic well-being

30 Sep 2023

Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Rice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique in rodents, and their findings suggest that the efficiency of gene delivery improves within each targeted site when more sites are opened.

27 Sep 2023

Senescent macrophages in the lung promote tumor growth, study finds

Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors.

25 Sep 2023

Machine learning speeds up virtual drug screening by 10-fold

Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers to carry out one of the world's largest virtual drug screens.

22 Sep 2023

Small Molecules News and Research

MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

New drug shows promise in killing cancer cells with genetic vulnerability

New antibody may offer effective drug treatment for breast cancer

Virginia Tech researchers develop new drug design framework to fight COVID-19

Study sheds light on how NAD+ levels decline with age in the ovaries, affecting fertility

Ensuring raw material quality in drug production and manufacturing

Drug Discovery 2023: A Conversation with Professor Janet Hemingway

Researchers spearhead a new method to hone in on new cancer drug targets

Artificial life forms could be used in the future for diagnosing and treating diseases

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

Trametinib: Potential therapeutic game-changer for Alzheimer's disease

UNH research seeks to quantify health outcomes based on food access, fiber intake and gut microbiota

Insights and new directions in basic, clinical research into neurodegenerative diseases

Rice researchers achieve noninvasive gene delivery to multiple brain regions

Senescent macrophages in the lung promote tumor growth, study finds

Machine learning speeds up virtual drug screening by 10-fold

New method detects microRNA targets at the level of single cells

Compound Management and its Crucial Role in Early Pharmaceutical Research

Scientists develop new technique to study sugars on immune cells

Unique openings in specific ion channels could lead to development of selective drugs

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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