Cell Biology News and Research

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How genetic abnormalities transform normal cells into leukemic cells

Cancer scientists led by Dr. John Dick at the Ontario Cancer Institute (OCI) and collaborators at St Jude Children's Research Hospital (Memphis) have found that defective genes and the individual leukemia cells that carry them are organized in a more complex way than previously thought.

21 Jan 2011

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads to cancer and other diseases.

19 Jan 2011

Cancer cells brought back under normal control

Scientists at The University of Nottingham have brought cancer cells back under normal control — by reactivating their cancer suppressor genes. The discovery could form a powerful new technology platform for the treatment of cancer of the breast and other cancers.

19 Jan 2011

7,8-Dihydroxyflavone holds potential for treatment of fear based disorders

Living a traumatic experience favours the persistence of fear associated with an aversive stimulus, known as fear conditioning and such effect, in mice, can be suppressed with a single dosis of 7,8-Dihydroxyflavone, a type of flavonoid which boosts the ability to acquire new emotional learnings.

13 Jan 2011

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

Research conducted by Iaroslav Savtchouk, a graduate student, and S. June Liu, PhD, Associate Professor of Cell Biology and Anatomy at LSU Health Sciences Center New Orleans, has shown that a single exposure to acute stress affected information processing in the cerebellum - the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation.

13 Jan 2011

All fat cells not the same

All fat cells are not the same - a fact that has implications in the understanding and treatment of type 2 diabetes and obesity, said researchers from Baylor College of Medicine (www.bcm.edu) in a report that appears in the current issue of the Journal of Cell Biology (http://www.jcb.rupress.org/).

10 Jan 2011

Slowing engines of mitochondria could extend life

In making your pro-longevity resolutions, like drinking more red wine and maintaining a vibrant social network, here's one you likely forgot: dialing down your mitochondria. It turns out that slowing the engines of these tiny cellular factories could extend your life-an observation relevant not only to aging research but to our understanding of how cells communicate with each another.

10 Jan 2011

Elevated fat and cholesterol levels in diet may play a role in breast cancer development

Elevated fat and cholesterol levels found in a typical American-style diet play an important role in the growth and spread of breast cancer, say researchers at the Kimmel Cancer Center at Jefferson.

7 Jan 2011

Administration of therapeutic hypothermia for TBI should depend on clinical condition of individual patients

Lowering the body temperature of patients soon after they have suffered a severe brain injury may reduce neurologic complications and improve outcomes. The safety of therapeutic hypothermia for traumatic brain injury (TBI) has been demonstrated in national studies. According to a Roundtable Discussion of renowned experts in the field, when and how it is administered should depend on the clinical condition of individual patients.

5 Jan 2011

Dutch scientists provide new insights into intestinal cancer through plant study

Dutch scientists have gained important new insights into intestinal cancer from studying a plant. The disease is called Peutz-Jeghers Syndrome, a hereditary disorder where people develop intestinal polyps that turn into malignant tumors.

5 Jan 2011

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

By sticking a chemical group to it at a specific site, a protein arrests an enzyme that may worsen and spread cancer, an international research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the January issue of Nature Cell Biology.

4 Jan 2011

Fondation Leducq awards Penn Medicine researcher $6M grant for cardiovascular disease study

An international team of researchers led by Daniel J. Rader, MD, associate director of Penn Medicine's Institute for Translational Medicine and Therapeutics, has received a $6 million grant from the Paris-based Fondation Leducq to study the molecular genetics of atherosclerotic cardiovascular disease. The team's proposal, "Molecular Mechanisms of Novel Genes Associated with Plasma Lipids and Cardiovascular Disease," was selected to receive the award through the Fondation's Transatlantic Networks of Excellence Program.

4 Jan 2011

New findings may solve mystery about how starvation hormone affects multiple biological systems

New findings by UT Southwestern Medical Center researchers may solve a 17-year-old mystery about how the so-called "starvation hormone" affects multiple biological systems, including preventing insulin sensitivity and promoting cell survival.

27 Dec 2010

AMPK activates autophagy by activating ATG1 enzyme

Researchers at the Salk Institute for Biological Studies have discovered how AMPK, a metabolic master switch that springs into gear when cells run low on energy, revs up a cellular recycling program to free up essential molecular building blocks in times of need.

24 Dec 2010

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

The cell signaling pathway known as Wnt, commonly activated in cancers, causes internal membranes within a healthy cell to imprison an enzyme that is vital in degrading proteins, preventing the enzyme from doing its job and affecting the stability of many proteins within the cell, researchers at UCLA's Jonsson Comprehensive Cancer Center have found.

24 Dec 2010

BioTime enters MTA with UC to make research-grade hES cell lines

BioTime, Inc. today announced a material transfer agreement (MTA) with the University of California (UC) system to make five research-grade human embryonic stem (hES) cell lines available to UC system researchers. These lines are genetically identical to a bank of GMP-compliant hES cell lines that will be made available to California-based researchers under a recent agreement between BioTime and the California Institute for Regenerative Medicine (CIRM).

23 Dec 2010

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Using fruit flies as a model to study embryo formation, scientists report in Nature Cell Biology that molecular breakdown of a protein called Bicoid is vital to normal head-to-tail patterning of the insect's offspring.

22 Dec 2010

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

The New York Stem Cell Foundation extends congratulations to Derrick Rossi, PhD, a member of the inaugural class of NYSCF-Robertson Investigators, who was named one of Time Magazine's 2010 "People Who Mattered" in the December 27, 2010 Person of the Year Issue.

22 Dec 2010

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

At the annual meeting of the American Society for Cell Biology last week in Philadelphia, researchers from Georgetown University Medical Center in Washington, D.C., announced that it may be possible for people with type 1 diabetes to grow their own insulin-producing cells, a breakthrough that could lead to a cure for the disease.

22 Dec 2010

Precision BioSciences receive $3 million to develop DNE technology

Precision BioSciences, today announced that it has been awarded over $3 million across four government grants. These grants were each awarded to Precision during the 4th Quarter of 2010 and came from the National Institute of Standards and Technology, the Treasury Department, the National Institute of Health, and the State of North Carolina.

16 Dec 2010

Cell Biology News and Research

How genetic abnormalities transform normal cells into leukemic cells

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

Cancer cells brought back under normal control

7,8-Dihydroxyflavone holds potential for treatment of fear based disorders

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

All fat cells not the same

Slowing engines of mitochondria could extend life

Elevated fat and cholesterol levels in diet may play a role in breast cancer development

Administration of therapeutic hypothermia for TBI should depend on clinical condition of individual patients

Dutch scientists provide new insights into intestinal cancer through plant study

CDK1 protein deactivates EZH2 enzyme that causes cancer spread

Fondation Leducq awards Penn Medicine researcher $6M grant for cardiovascular disease study

New findings may solve mystery about how starvation hormone affects multiple biological systems

AMPK activates autophagy by activating ATG1 enzyme

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

BioTime enters MTA with UC to make research-grade hES cell lines

Molecular breakdown of Bicoid protein vital for normal patterning of fruit fly's offspring

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

People with type 1 diabetes could grow their own insulin-producing cells, say researchers

Precision BioSciences receive $3 million to develop DNE technology

Cell Density eBook - What are the Many Applications of Cell Density Sensors? eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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