Clinical Trial News and Research

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New drug molecule restores lost nerve-muscle connections, enhances strength

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found.

11 Oct 2023

Saline injection treatment for calcific tendinopathy provides no meaningful benefit over placebo

A saline injection treatment widely used for calcific tendinopathy - a common, painful condition caused by a build-up of calcium in the rotator cuff tendons of the shoulder - provides no meaningful benefit over placebo, concludes a trial published by The BMJ today.

11 Oct 2023

World-first clinical trial offers new hope in the treatment of mild cognitive impairment among older people

Western Sydney University's NICM Health Research Institute has led a world-first clinical trial in Australia that offers new hope in the treatment of mild cognitive impairment (MCI) among older people.

11 Oct 2023

UArizona to train next generation of Alzheimer's researchers with prestigious NIH grant

A prestigious National Institute on Aging training grant to develop a future workforce of research scientists in the field of Alzheimer's disease and related dementias was awarded to researchers at the Center for Innovation in Brain Science at the University of Arizona Health Sciences.

11 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

Recent Advancements in Cell Based Therapy

In this interview, NewsMedical talks to James Brady about cell-based therapy and how the field of genetic engineering transformed.

From MaxCyte, Inc. 11 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

HKU-developed antibiotic drug to enter clinical trials in Mainland China

A new antibiotic drug developed by a research team led by Professor Li Xuechen from the Department of Chemistry at The University of Hong Kong (HKU) has recently gained approval from the authorities to undergo clinical trials in the Mainland.

10 Oct 2023

Can a low-carb, anti-inflammatory diet be the answer to long COVID woes?

Keck Medicine of USC is conducting a clinical trial to determine if a low-carbohydrate, anti-inflammatory diet combined with a medical food raising blood ketone levels can alleviate symptoms of long COVID. The study, based on the theory that prolonged inflammation post-COVID infection causes the syndrome, aims to examine the diet's efficacy in reducing inflammation and improving patients' health.

10 Oct 2023

Multilevel intervention reduces barriers to timely cancer screening follow-up

When cancer screening in a patient reveals an abnormal test result, prompt follow-up is critical so that further tests can be conducted, and if needed, treatment can be initiated as soon as possible.

10 Oct 2023

Nasal mupirocin found to be highly effective at preventing Staphylococcus aureus infections in critically ill patients

A large multi-state study by the Centers for Disease Control and Prevention, the Harvard Pilgrim Health Care Institute, HCA Healthcare, and the University of California, Irvine has found that a nasal antibiotic ointment, mupirocin, which is currently used daily for intensive care unit (ICU) patients in only one-third of U.S. hospitals, is highly effective at preventing Staphylococcus aureus infections in critically ill patients, outperforming an antiseptic solution.

10 Oct 2023

Owlstone Medical recruits first patient in phase 2 clinical trial for the early detection of lung cancer through breath biopsy

Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced recruitment of the first patient into its EVOLUTION Phase 2 clinical trial following successful achievement of key safety and proof of concept milestones in Phase 1.

From Owlstone Medical Ltd 10 Oct 2023

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells).

9 Oct 2023

New drug shows promise for epilepsy patients with resistant seizures

In cases where standard therapies fail, a medication called XEN1101 reduces seizure frequency by more than 50% in some patients and sometimes eliminates them altogether, a new study shows.

9 Oct 2023

New clinical trial investigates diet to ease long COVID symptoms

Approximately 7% of Americans have had long COVID, a range of ongoing health problems experienced after infection and recovery from COVID-19. Symptoms can include fatigue, brain fog, headaches, chest pain, heart palpitations and more.

9 Oct 2023

Solriamfetol may be an effective alternative for managing ADHD in adults, trial shows

Although several medications are approved to treat attention-deficit/hyperactivity disorder (ADHD), some individuals experience limited benefits from the drugs or develop side effects from their use.

9 Oct 2023

Drug Discovery 2023: A Conversation with Professor Janet Hemingway

We spoke to Professor Janet Hemingway, founding Director of iiCON and Professor of Tropical Medicine at Liverpool School of Tropical Medicine.

From ELRIG (UK) Ltd. 9 Oct 2023

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Using antigenic cartography, researchers analyzed cross-reactivity patterns of SARS-CoV-2 variants and the effect of spike-protein changes on post-infection and vaccination immune responses. The study illuminated unique neutralization profiles and underscored the evolving defense mechanisms with repeated immunizations.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Researchers develop innovative treatment option for therapy-resistant epilepsy

Neuroscientist Professor Sonja Bröer from Freie Universität Berlin is involved in the development of an innovative treatment option for therapy-resistant epilepsy.

6 Oct 2023

Clinical Trial News and Research

New drug molecule restores lost nerve-muscle connections, enhances strength

Saline injection treatment for calcific tendinopathy provides no meaningful benefit over placebo

World-first clinical trial offers new hope in the treatment of mild cognitive impairment among older people

UArizona to train next generation of Alzheimer's researchers with prestigious NIH grant

Pitt scientists develop new approach to reduce side effects of organ transplants

Recent Advancements in Cell Based Therapy

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

HKU-developed antibiotic drug to enter clinical trials in Mainland China

Can a low-carb, anti-inflammatory diet be the answer to long COVID woes?

Multilevel intervention reduces barriers to timely cancer screening follow-up

Nasal mupirocin found to be highly effective at preventing Staphylococcus aureus infections in critically ill patients

Owlstone Medical recruits first patient in phase 2 clinical trial for the early detection of lung cancer through breath biopsy

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

New drug shows promise for epilepsy patients with resistant seizures

New clinical trial investigates diet to ease long COVID symptoms

Solriamfetol may be an effective alternative for managing ADHD in adults, trial shows

Drug Discovery 2023: A Conversation with Professor Janet Hemingway

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

Researchers develop innovative treatment option for therapy-resistant epilepsy

eBook: Using iPSCs models for human disease research and drug discovery eBook

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