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FDA approves more drugs based on single trials and less public disclosure of results

The U.S. Food and Drug Administration is approving more novel pharmaceutical drugs based on single clinical trials and with less public disclosure about those trials than was the norm just a few years ago, a pair of recent studies from Oregon State University found.

24 Aug 2023

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

A stem cell patch developed by USC researchers for patients with macular degeneration will soon be tested in a phase 2b clinical trial.

24 Aug 2023

New model predicts 10-year risk of dying from breast cancer

A team of researchers at the University of Oxford, led by the Nuffield Department of Primary Care Health Sciences, have developed a new model that reliably predicts a woman's likelihood of developing and then dying of breast cancer within a decade.

24 Aug 2023

Pioneering drug for rare kidney disease improves outcome for patients

A pioneering drug for a rare kidney disease prevents organ failure and significantly improves the outcome for patients, new research has confirmed.

24 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Griffith on the brink of technological breakthrough in vaccine development

Griffith University researchers are on the brink of a technological breakthrough in vaccine development with a possible new vaccine modality.

23 Aug 2023

NIH awards $3 million grant to study synbiotic medical food for bone health in older women

The NIH/National Institute on Aging has awarded a R01 $3 million grant to study the impact of a probiotic/prebiotic (synbiotic) medical food developed by Solarea Bio on maintaining bone health of older women.

23 Aug 2023

Taking adult education classes may help prevent dementia

How can we best keep our brain fit as we grow older? It's well known that regular cognitive activity, for example brainteasers, sudokus, or certain video games in middle and old age tends to protect against cognitive decline and dementias like Alzheimer's.

23 Aug 2023

$9.57 million grant will support a clinical trial to study new treatment option for NAFLD

According to the National Institutes of Health, approximately 24% of adults in the United States have nonalcoholic fatty liver disease (NAFLD), an umbrella term for a range of liver conditions affecting people who drink little to no alcohol that can lead to cirrhosis, liver cancer and liver failure.

23 Aug 2023

Project NextGen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics

Funding includes $1 billion for vaccine clinical trials, $326 million for a new monoclonal antibody, and $100 million to explore novel vaccine and therapeutic technologies.

23 Aug 2023

Home-based oxygen therapy shows promise for improving wound healing after breast reduction surgery

In the last few years, breast reduction procedures in the U.S. have become increasingly common. According to the American Society of Plastic Surgeons, nearly 100,000 breast reduction procedures were performed in 2020.

22 Aug 2023

Malaria vaccine and drug combination reduces hospitalizations, deaths in children

The final results of a landmark study published in The Lancet Infectious Diseases confirm that the benefits of combining the RTS,S/AS01E (RTS,S) malaria vaccine with antimalarial drugs in settings of highly seasonal malaria transmission continue over five years.

22 Aug 2023

UVA Health launches clinical trial to determine if focused ultrasound can help people quit cocaine

Pioneering researchers at UVA Health are testing whether focused sound waves can help people overcome cocaine addiction, a growing problem across the nation.

22 Aug 2023

What is the effect of a workplace-based nutritional and behavioral intervention on adherence to Mediterranean diet principles at 12 months?

The impact of nutritional and behavioral intervention on adherence to the Mediterranean diet among US firefighters.

22 Aug 2023

Doctors advocate fresh efforts to combat Chagas disease, a silent killer

When Maira Gutiérrez was diagnosed with Chagas disease in 1997, neither she nor her primary care physician had even heard of the malady. She discovered her illness only by chance, after participating in a Red Cross blood drive organized by her employer, Universal Studios.

22 Aug 2023

Investigating alcohol use, mental health status, and alcohol-related problems in university students amid the COVID-19 pandemic

Researchers investigated alcohol usage, psychological health status, and alcohol-associated concerns among university students.

22 Aug 2023

Clinical Trial News and Research

FDA approves more drugs based on single trials and less public disclosure of results

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

New model predicts 10-year risk of dying from breast cancer

Pioneering drug for rare kidney disease improves outcome for patients

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Griffith on the brink of technological breakthrough in vaccine development

NIH awards $3 million grant to study synbiotic medical food for bone health in older women

Taking adult education classes may help prevent dementia

$9.57 million grant will support a clinical trial to study new treatment option for NAFLD

Project NextGen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics

Home-based oxygen therapy shows promise for improving wound healing after breast reduction surgery

Malaria vaccine and drug combination reduces hospitalizations, deaths in children

UVA Health launches clinical trial to determine if focused ultrasound can help people quit cocaine

What is the effect of a workplace-based nutritional and behavioral intervention on adherence to Mediterranean diet principles at 12 months?

Doctors advocate fresh efforts to combat Chagas disease, a silent killer

Investigating alcohol use, mental health status, and alcohol-related problems in university students amid the COVID-19 pandemic

Simple blood test may predict risk of progressive heart and kidney disease in people with diabetic kidney disease

Time-restricted feeding may correct the circadian disruptions in Alzheimer's disease

Microbiome-directed foods boost child nutrition

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

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