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Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

A research team at the University of Turku in Finland discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients.

11 Sep 2018

Scientists develop first non-antibiotic drug to treat tuberculosis in animals

Scientists at The University of Manchester have developed the first non-antibiotic drug to successfully treat tuberculosis in animals.

11 Sep 2018

Molecule produced during fasting appears to have anti-aging effects on vascular system

A molecule produced during fasting or calorie restriction has anti-aging effects on the vascular system, which could reduce the occurrence and severity of human diseases related to blood vessels, such as cardiovascular disease, according to a study led by Georgia State University.

11 Sep 2018

BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

BioIVT, a leading provider of research models and services for drug development, today announced its research into the mechanisms involved in cholestatic drug-induced liver injury has been published in Applied In Vitro Toxicology.

10 Sep 2018

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Older adults who frequently report feeling sleepy during the day are three times more likely to develop Alzheimer's in later life, according to a new study.

7 Sep 2018

Researchers synthesize new antibacterial polymers without hydrophobic alkyl chains

Artificial polymers, like antibiotic peptides, need both hydrophobic and hydrophilic domains in their molecular structure to exert antibacterial activity.

7 Sep 2018

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.

6 Sep 2018

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma.

6 Sep 2018

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Researchers at the National Center for Advancing Translational Sciences, part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme implicated in a number of cancers.

6 Sep 2018

Plant-derived substance could offer new option for treatment of obesity

A plant-derived substance widely used in traditional Chinese medicine has demonstrated promising weight loss effects.

31 Aug 2018

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

A $2 million phase 2 Small Business Technology Transfer grant to optimize a promising new compound that has shown efficacy in preclinical studies against treatment-resistant multiple myeloma has been awarded to a Medical University of South Carolina startup company, Leukogene Therapeutics, Inc., in collaboration with MUSC researcher and company founder, Nathan G. Dolloff, Ph.D. Dolloff is an assistant professor in the Department of Cell and Molecular Pharmacology & Experimental Therapeutics at MUSC and a member of MUSC Hollings Cancer Center.

31 Aug 2018

HKBU chemists discover metal-based inhibitor to treat triple-negative breast cancer

Chemists at Hong Kong Baptist University have discovered the use of a metal compound that inhibits the enzyme closely associated with triple-negative breast cancer, one of the most difficult forms of breast cancer to treat.

30 Aug 2018

Component of cannabis could help in psychosis

Researchers from King’s College London have now found how the chemical cannabidiol or CBD from cannabis can reduce the abnormal brain activity in patients who are at risk of psychosis. The study was published in the latest issue of the journal JAMA Psychiatry.

30 Aug 2018

Researchers take major step forward in finding safe and non-addictive pain killer

With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.

30 Aug 2018

Researchers uncover why some cancers grow faster than others

University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor in U of T's Donnelly Centre for Cellular and Biomolecular Research, has identified a protein called NUAK2, which is produced by cancer cells to boost their proliferation and whose presence in tumors is associated with poor disease prognosis.

29 Aug 2018

Study explores effects of combined, isolated use of cannabis and nicotine on the brain

Researchers at the Center for BrainHealth® at the University of Texas at Dallas investigated the effects on the brain of concurrent cannabis and nicotine use, versus the use of solely cannabis and solely nicotine.

29 Aug 2018

Biochemist's startup secures license for developing technology that could treat PTSD

A biochemist's startup company announced Monday that it had secured an exclusive patent license agreement with the Air Force Research Laboratory for a breakthrough technology that could help military veterans suffering from a post-traumatic stress disorder.

28 Aug 2018

Researchers develop new system for effective cancer diagnosis and treatment

A research group consisting of scientists from NUST MISIS, the Technical University of Munich, Helmholtz Zentrum München, the University of Duisburg-Essen, and the University of Oldenburg has developed a system that allows doctors to both improve the accuracy of diagnosing malignant cells and to provide additional opportunities for cancer treatment.

24 Aug 2018

Proteins that protect neurons from destruction can be delivered through nose

Protective proteins that mitigate the destruction of nerve cells after a stroke can be administered into the brain through the nose, as Heidelberg University researchers demonstrated using a mouse model.

24 Aug 2018

Compound News and Research

Synergism between HOXB13 and CIP2A genes predisposes men to get prostate cancer

Scientists develop first non-antibiotic drug to treat tuberculosis in animals

Molecule produced during fasting appears to have anti-aging effects on vascular system

BioIVT announces research into mechanisms involved in cholestatic drug-induced liver injury

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Researchers synthesize new antibacterial polymers without hydrophobic alkyl chains

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Plant-derived substance could offer new option for treatment of obesity

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

HKBU chemists discover metal-based inhibitor to treat triple-negative breast cancer

Component of cannabis could help in psychosis

Researchers take major step forward in finding safe and non-addictive pain killer

Researchers uncover why some cancers grow faster than others

Study explores effects of combined, isolated use of cannabis and nicotine on the brain

Biochemist's startup secures license for developing technology that could treat PTSD

Researchers develop new system for effective cancer diagnosis and treatment

Proteins that protect neurons from destruction can be delivered through nose

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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