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Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

Should older seniors risk major surgery? New research offers guidance

Nearly 1 in 7 older adults die within a year of undergoing major surgery, according to an important new study that sheds much-needed light on the risks seniors face when having invasive procedures.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

Scientists develop preclinical model of scrub typhus disease

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis, and immune responses. The study has been published in the journal PLOS Neglected Tropical Diseases.

27 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Additional six weeks of anti-clotting treatment reduces further clot risk after distal DVT

Giving the anti-clotting drug rivaroxaban to patients for 12 weeks instead of the usual six after a blood clot in the lower leg reduces the risk of further clots developing up to two years after treatment, finds a trial published by The BMJ today.

24 Nov 2022

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

Patients with inflammatory bowel diseases (IBD) who required treatment with biologic therapies and were enrolled in a financial assistance program were less likely to need surgery after starting medication than those not enrolled in a program, a study by UT Southwestern researchers found.

23 Nov 2022

Maternal obesity during pregnancy causes metabolic perturbations in offspring's liver and skeletal muscle

A recent study in The FASEB Journal has identified metabolic perturbations in the liver and skeletal muscle of young nonhuman primates on normal diets whose mothers were obese during pregnancy.

23 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

OSU researchers develop novel nanomedicine technique for diagnosing and ending ectopic pregnancies

Oregon State University scientists have produced a proof of concept for a new and better way of caring for women facing the life-threatening situation of ectopic pregnancy, which occurs when a fertilized egg implants somewhere other than the lining of the uterus.

22 Nov 2022

Remdesivir appears to make a big difference in Japanese patients with COVID-19

The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.

22 Nov 2022

New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

Cost-saving Medicare Advantage may be a disadvantage for complex cancer surgery patients

An analysis by researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, found that cancer patients with privatized, cost-saving Medicare Advantage were more likely than those with traditional Medicare to go to hospitals with physicians less experienced at performing complicated surgeries, and that they were more likely to die within the first 30 days after the removal of their stomach, pancreas or liver.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Honey improves key measures of health, including blood sugar and cholesterol levels

Researchers look to better understand the impact of honey on mitigating certain cardiometabolic risk factors.

20 Nov 2022

Liver News and Research

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Should older seniors risk major surgery? New research offers guidance

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

Scientists develop preclinical model of scrub typhus disease

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Additional six weeks of anti-clotting treatment reduces further clot risk after distal DVT

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

Maternal obesity during pregnancy causes metabolic perturbations in offspring's liver and skeletal muscle

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

OSU researchers develop novel nanomedicine technique for diagnosing and ending ectopic pregnancies

Remdesivir appears to make a big difference in Japanese patients with COVID-19

New studies improve understanding of the genetic factors that protect people against COVID-19

Kiwira virus: a new bat-borne hantavirus detected in Africa

Cost-saving Medicare Advantage may be a disadvantage for complex cancer surgery patients

Study suggests bats are an underrecognized arenavirus reservoir

MIT researchers develop new technique for genome-wide studies of the liver

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Honey improves key measures of health, including blood sugar and cholesterol levels

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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