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New technique to grow blood vessels could accelerate growth of regenerative medicine

In addition the technique to grow the blood vessels in a 3D scaffold cuts down on the risk of transplant rejection because it uses cells from the patient. It was developed by researchers from the University of Bath's Department of Pharmacy and Pharmacology, working with colleagues at Bristol Heart Institute.

25 May 2016

Study finds link between sodium intake and clinical CVD events in CKD patients

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

25 May 2016

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny, designer packages.

23 May 2016

Phase I study of triple drug combination shows promise in multiple myeloma patients

PharmaMar announces the positive results from a Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma.

21 May 2016

New experimental model may predict eventual cardiac phenotype in pediatric patients

An experimental model uses genetics-guided biomechanics and patient-derived stem cells to predict what type of inherited heart defect a child will develop, according to authors of a new study in the journal Cell.

21 May 2016

New frozen faecal bank increases chances of curing a chronic health condition

A new frozen faecal bank that could save hundreds of lives and dramatically improve the quality of life of many more has been established at a Portsmouth hospital.

20 May 2016

Penn State researchers link mutation in common virus to fatal brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

19 May 2016

$Allogeneic HSCT offers good survival for select TKI-refractory CML patients$

Allogeneic HSCT offers good survival for select TKI-refractory CML patients

Allogeneic hematopoietic stem cell transplantation is associated with a high rate of survival for carefully chosen chronic myeloid leukaemia patients who do not respond well to tyrosine kinase inhibitor therapy, research suggests.

18 May 2016

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

The Cell and Gene Therapy Catapult and University of Aberdeen, UK, today announce the creation of Islexa, a new company developing a novel technology to produce laboratory grown islets, the organoids responsible for insulin production.

18 May 2016

New E-Vac therapy may be promising treatment option for GI leaks

Gastroenterologists on the medical staff at Baylor University Medical Center at Dallas are evaluating a new procedure for patients with gastrointestinal (GI) leaks and perforations, a complication that can result from laparoscopic surgery on the esophagus, stomach and small intestines—and outcomes have been promising.

13 May 2016

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Investigators have uncovered a "weekend effect" contributing to the worsening availability of donor kidneys in the United States. They found that kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend (89.5% on the weekend vs. 90.2% during the week).

13 May 2016

Simple, cheap chemical sensors may detect developing cancers in future

Many cancers could be successfully treated if the patient consulted the doctor sufficiently early. But how can a developing cancer be detected if it doesn't give rise to any symptoms? In the near future, suitably early diagnosis could be provided by simple and cheap chemical sensors - thanks to special recognizing polymer films developed at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw.

12 May 2016

New IsoPSA test identifies molecular structural changes in protein biomarkers to detect prostate cancer

A promising new test is detecting prostate cancer more precisely than current tests, by identifying molecular changes in the prostate specific antigen (PSA) protein, according to Cleveland Clinic research presented today at the American Urological Association annual meeting.

12 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

New light-based technique may offer improved treatment for eye problems

Researchers have developed a new light-based technique that selectively stiffens tissue in the cornea and might one day offer improved treatment for eye problems caused by weakened corneal tissue.

5 May 2016

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

In the late 1980s and over the 1990s, researchers at Lund University in Sweden pioneered the transplantation of new nerve cells into the brains of patients with Parkinson's disease. The outcomes proved for the first time that transplanted nerve cells can survive and function in the diseased human brain. Some patients showed marked improvement after the transplantation while others showed moderate or no relief of symptoms.

4 May 2016

Researchers safely transplant stem cells from patient's skin to the eye to restore vision

Researchers have safely transplanted stem cells derived from a patient's skin to the back of the eye in an effort to restore vision. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Seattle, Wash.

4 May 2016

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18. The research was funded by National Institute of Health grants through the National Institute of Allergy and Infectious Diseases and the National Institute for Diabetes and Digestive and Kidney Disease.

3 May 2016

Study examines role of intraventricular transplantation of bone marrow mesenchymal stem cell in stroke patients

Winner of the American Association of Neurological Surgeons International Travel Scholarship, Asra Al Fauzi, MD, IFAANS, presented his research, Intraventricular Transplantation of Autologous Bone Marrow Mesenchymal Stem Cell in Hemorrhagic Stroke, during the 2016 AANS Annual Scientific Meeting.

3 May 2016

Bioengineers develop synthetic bed to nurture colonies of human embryonic stem cells

The most productive way scientists have devised to nurture colonies of human embryonic stem cells is to do so atop a bed of mouse cells. That may be fine for lab research, but it poses an unacceptable contamination risk for stem cells intended for transplant into human patients. In a new study, Brown University bioengineers have developed a synthetic bed that works about as well as the mouse cells, called fibroblasts, without any possibility of contamination.

3 May 2016

Transplant News and Research

New technique to grow blood vessels could accelerate growth of regenerative medicine

Study finds link between sodium intake and clinical CVD events in CKD patients

Small lipid nanocarrier may deliver chemotherapeutic drug more efficiently to brain tumor cells

Phase I study of triple drug combination shows promise in multiple myeloma patients

New experimental model may predict eventual cardiac phenotype in pediatric patients

New frozen faecal bank increases chances of curing a chronic health condition

Penn State researchers link mutation in common virus to fatal brain disease

Allogeneic HSCT offers good survival for select TKI-refractory CML patients

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

New E-Vac therapy may be promising treatment option for GI leaks

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Simple, cheap chemical sensors may detect developing cancers in future

New IsoPSA test identifies molecular structural changes in protein biomarkers to detect prostate cancer

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

New light-based technique may offer improved treatment for eye problems

Lund study shows transplanted nerve cells can survive for many years in diseased human brain

Researchers safely transplant stem cells from patient's skin to the eye to restore vision

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Study examines role of intraventricular transplantation of bone marrow mesenchymal stem cell in stroke patients

Bioengineers develop synthetic bed to nurture colonies of human embryonic stem cells

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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