Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New genetic test could help avoid unnecessary prostate cancer surgery

Men who develop prostate cancer could avoid having unnecessary surgery or radiotherapy thanks to a new, more precise genetic test which is being trialed in Leeds.

25 Sep 2019

Urine test for detection of early-stage pancreatic cancer reaches final stage of validation

A urine test that can detect early stage pancreatic cancer has reached the final stage of validation before being developed for use with patients.

25 Sep 2019

New test to establish integrity of biosamples used in medical research

Effective diagnosis and treatment of disease draws on painstaking research, which often relies on biological samples.

23 Sep 2019

New discovery may revolutionize treatment of drug-resistant epilepsy

Researchers at Carnegie Mellon University have discovered that the spreading of seizures through the brain can be suppressed depending on the amount of pressure within the brain, an important discovery that may revolutionize the treatment of drug-resistant epilepsy.

23 Sep 2019

Cutting-edge technologies to improve drug development while reducing animal testing

On Thursday, September 19th, 2019, the Physicians Committee for Responsible Medicine hosted a congressional briefing in cooperation with Rep. Brendan Boyle (D-Pa.), featuring innovator companies showcasing cutting-edge technologies that have the potential to improve the safety and efficacy of pharmaceuticals while reducing animal testing.

20 Sep 2019

Research: Metformin may be effective in treating breast cancer that lacks Nischarin protein

Research conducted by Suresh Alahari, PhD, Professor of Biochemistry and Genetics at LSU Health New Orleans School of Medicine, has found that metformin, a commonly prescribed drug for Type 2 Diabetes, may be effective in treating cancers that lack a protein called Nischarin.

20 Sep 2019

Quanterix Serum Nf-L assay powers key trial and study results presented at ECTRIMS 2019

Quanterix, announce that its Simoa technology and Nf-L assays were used in many of the groundbreaking research and treatment developments.

From Quanterix 18 Sep 2019

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

Initial results of NRG Oncology Clinical Trial RTOG 9601 in men with biochemically recurrent prostate cancer receiving salvage radiotherapy demonstrated improvement in OS from the addition of long-term hormone therapy to SRT.

17 Sep 2019

Cellular metabolic overactivity leads to inflammation, research reveals

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased.

16 Sep 2019

Researchers identify changes in retinal layers of patients with mild Alzheimer's disease

Researchers at the Complutense University of Madrid have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer's disease, confirming that the retina is one of the most important biomarkers for early diagnosis of the disease.

13 Sep 2019

Breath-based tests could benefit from modeling of the underlying biology

Breath-based tests are gaining in popularity as a non-invasive diagnostic tool for a growing number of medical conditions. Research into improving the collection and analysis of these tests will be presented today at the American Physiological Society Interface of Mathematical Models and Experimental Biology: Role of the Microvasculature Conference in Scottsdale, Ariz.

13 Sep 2019

Discovery opens up new opportunities to understand the genetics of cancer

University of Delaware molecular biologist Mona Batish and collaborators at Harvard Medical School and University of California, Los Angeles, have identified a new circular ribonucleic acid (RNA) that increases tumor activity in soft tissue and connective tissue tumors.

13 Sep 2019

Novel protein biomarker can help improve dementia risk prediction

Identifying those who are at risk of dementia, a type of neurodegenerative disease, is crucial for early treatment and development of new therapies, a new study suggests.

11 Sep 2019

Quanterix Simoa technology powers Multiple Sclerosis Research with more than 50 presentations at ECTRIMS 2019

Quanterix announced ultra-sensitive Simoa technology has been referenced in more than 50 new research studies to be presented.

From Quanterix 11 Sep 2019

EEG slowing may be a valuable biomarker for delirium severity

An EEG (electroencephalogram) can provide a valuable biomarker for detecting delirium, a serious mental disturbance that is often underrecognized, as well as predicting poor clinical outcomes, researchers from Massachusetts General Hospital have found.

11 Sep 2019

Non-invasive accurate blood test for prostate cancer

For men, one of the most dreaded moments could be hearing, “We’re not yet sure, but your PSA is high; you’ll have to come for further tests.” This could start a chain of events which ends in the diagnosis of prostate cancer - including a prostate biopsy, and ending in a major surgery for prostate removal.

11 Sep 2019

Biomarker News and Research

Further Reading

New genetic test could help avoid unnecessary prostate cancer surgery

Urine test for detection of early-stage pancreatic cancer reaches final stage of validation

New test to establish integrity of biosamples used in medical research

New discovery may revolutionize treatment of drug-resistant epilepsy

Cutting-edge technologies to improve drug development while reducing animal testing

Research: Metformin may be effective in treating breast cancer that lacks Nischarin protein

Quanterix Serum Nf-L assay powers key trial and study results presented at ECTRIMS 2019

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

Cellular metabolic overactivity leads to inflammation, research reveals

Researchers identify changes in retinal layers of patients with mild Alzheimer's disease

Breath-based tests could benefit from modeling of the underlying biology

Discovery opens up new opportunities to understand the genetics of cancer

Novel protein biomarker can help improve dementia risk prediction

Quanterix Simoa technology powers Multiple Sclerosis Research with more than 50 presentations at ECTRIMS 2019

EEG slowing may be a valuable biomarker for delirium severity

Non-invasive accurate blood test for prostate cancer

Simple blood test found to efficiently, accurately detect aggressive prostate cancer

Gut microbiome could be used to predict individual's risk of bowel cancer

Lung-MAP study: Majority of cancer patients don't understand genomic test results

New blood test could aid earlier and precise diagnosis of lung cancer

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo