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Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

Environmental surface testing at radiation oncology clinic showed no detectable SARS-CoV2

A Rutgers Cancer Institute of New Jersey study shows environmental surface testing at the center's Radiation Oncology Department located within Robert Wood Johnson University Hospital, an RWJBarnabas Health facility, during the height of the COVID-19 pandemic in the state showed no detectable SARS-CoV2 – the virus that causes COVID-19

28 Aug 2020

Vertebral body tethering yields promising results in scoliosis patients

Scoliosis is the most common spinal deformity affecting pediatric patients. A posterior spinal fusion (PSF) is the gold standard treatment for patients with curves exceeding 45 degrees, but the procedure's drawbacks include the loss of spinal mobility, persistent pain and adjacent segment disc disease.

27 Aug 2020

Young children’s early eating habits linked to later autistic-like personality traits

New research from Edith Cowan University has shown a link between young children’s early eating habits and higher levels of traits associated with autism as adults.

27 Aug 2020

Study offers hope for treatment of Krabbe disease

In one out of 100,000 infants, a mutation in the GALC gene causes an incurable, always fatal disorder known as infantile Krabbe disease, or globoid cell leukodystrophy. Most children with the condition die before they turn 2.

26 Aug 2020

$Study identifies link between hip fracture risk and nanoscale bone inflexibility$

Study identifies link between hip fracture risk and nanoscale bone inflexibility

The study led by Imperial College London found that flexibility, as well as density, in the bone nanostructure is an important factor in assessing how likely someone is to suffer fractures.

26 Aug 2020

Higher dosage of opioids for outpatient knee surgery is linked to increased risk of overdose death

A new study published in BMJ Open found that opioid prescription rates for outpatient knee surgery vary widely across the country, but the strength of the average prescription in the United States is at a level that has been linked to an increased risk of overdose death.

26 Aug 2020

Vitamin D supplements do not prevent severe asthma attacks in children

Contrary to earlier results, vitamin D supplements do not prevent severe asthma attacks in at-risk children, according to the first placebo-controlled clinical trial to test this relationship.

25 Aug 2020

Allowing low-level CMV infection may boost immunity in stem cell transplant recipients

Patients who develop cytomegalovirus infections after allogeneic stem cell transplantation may be able to develop an immunity against the virus, strengthen their immune system and reduce reliance on strong antiviral medications, a team of cellular-therapy specialists from Roswell Park Comprehensive Cancer Center has found.

25 Aug 2020

New, low-cost technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

24 Aug 2020

$Prolonged use of bisphosphonates increases risk of atypical femur fractures$

Prolonged use of bisphosphonates increases risk of atypical femur fractures

The risk of atypical femur fractures increases with prolonged use of bisphosphonates, drugs commonly used to treat osteoporosis, according to a new study.

24 Aug 2020

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center’s Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.

21 Aug 2020

Girls with anorexia nervosa can have stunted growth

Girls with anorexia nervosa can have stunted growth and may not reach their full height potential, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Aug 2020

Microbial diversity can improve treatment for cancer patients

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

19 Aug 2020

Study: Vitamin D supplementation is associated with compositional changes in a baby's microbiome

New research from the CHILD Cohort Study has shed light on the influence of vitamin D supplementation on a baby's developing gut microbiome.

19 Aug 2020

Antibody and cellular immunity in severe vs. mild COVID-19

Now, a new study published in the journal Signal Transduction and Targeted Therapy in August 2020 shows that while humoral and T-cell immune responses are more robust in severe infection, the disease activates memory T cells as part of the adaptive immune system in COVID-19 patients irrespective of disease severity.

18 Aug 2020

Bone News and Research

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Environmental surface testing at radiation oncology clinic showed no detectable SARS-CoV2

Vertebral body tethering yields promising results in scoliosis patients

Young children’s early eating habits linked to later autistic-like personality traits

Study offers hope for treatment of Krabbe disease

Study identifies link between hip fracture risk and nanoscale bone inflexibility

Higher dosage of opioids for outpatient knee surgery is linked to increased risk of overdose death

Vitamin D supplements do not prevent severe asthma attacks in children

Allowing low-level CMV infection may boost immunity in stem cell transplant recipients

New, low-cost technology for subcutaneous injection of viscous formulations

Prolonged use of bisphosphonates increases risk of atypical femur fractures

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

Girls with anorexia nervosa can have stunted growth

Microbial diversity can improve treatment for cancer patients

Study: Vitamin D supplementation is associated with compositional changes in a baby's microbiome

Antibody and cellular immunity in severe vs. mild COVID-19

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Gene editing approach removes oral herpes

High intensity physical activity in early life can prevent osteoporosis in later life

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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