Clinical Trial News and Research

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Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

18 Aug 2023

E-cigarette usage nudges people toward quitting smoking, study shows

E-cigarettes do have value as a smoking cessation aid, according to a new study just released by a team of MUSC Hollings Cancer Center researchers.

18 Aug 2023

Medicaid expansion increases cancer clinical trial participation

The Medicaid expansion under the Patient Protection and Affordable Care Act resulted in a 19% annual increase in Medicaid-insured cancer patients participating in publicly funded clinical trials, according to researchers from Fred Hutchinson Cancer Center, the SWOG Statistics and Data Management Center and Columbia University.

18 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

Immunotherapy combination extends progression-free survival in patients with melanoma

A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

17 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Only a small percentage of older adults with early Alzheimer's eligible for new treatments

Only a small percentage of older adults who are in the early stages of Alzheimer's disease meet the eligibility criteria to receive new monoclonal antibody treatments, drugs that target amyloid-ß plaques in the brain, an early sign of Alzheimer's disease.

16 Aug 2023

Some early-stage, low-risk breast cancer patients may not need radiotherapy after surgery

Some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery according to new research led by McMaster University, BC Cancer, Hamilton Heath Sciences, and the University of British Columbia.

16 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Study highlights the delay in advanced stroke care and treatments

A new study from the University of Chicago Medicine reveals that nearly 75 percent of acute stroke patients wait more than two hours to be transferred to a comprehensive stroke center - a delay in advanced care and treatments that risks long-term disability.

16 Aug 2023

Natural bioactive molecules can relieve cold and flu symptoms

Researchers at Applied Biological Laboratories Inc. discovered how natural bioactive molecules can effectively relieve cold and flu symptoms by protecting the mucosal barrier function and reducing inflammation during these infections.

16 Aug 2023

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have identified a cell metabolism process found in men with diabetes and metastatic prostate cancer that could one day lead to improved testing and treatments for Black men with these diseases.

15 Aug 2023

Proton radiotherapy used for the first time in Switzerland to treat esophageal tumor

A 67-year-old patient presenting with esophageal cancer was treated today at the Paul Scherrer Institute PSI with a form of radiation provided by protons, i.e. positively charged particles.

15 Aug 2023

Study discovers new mechanism for deadly tumor switch in prostate cancer

A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.

14 Aug 2023

Intensive lifestyle intervention linked to increased employment for people with type 2 diabetes

USC Schaeffer Center and University of Minnesota researchers found that study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.

14 Aug 2023

Study examines the relationship between consumption of fatty acids and diabetic retinopathy

Researchers examined the relationship between dietary fatty acid (FA) intake and diabetic retinopathy (DR).

14 Aug 2023

A blood test that screens for cancer: Does it do more harm than good?

By summer 2021, Gilbert Milam Jr. was living a good life. A nationally renowned rapper who performs under the name Berner, Milam was also enjoying the global expansion of Cookies, a brand of cannabis products and clothing that he co-founded and was running as CEO.

11 Aug 2023

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants.

11 Aug 2023

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial.

10 Aug 2023

Clinical Trial News and Research

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

E-cigarette usage nudges people toward quitting smoking, study shows

Medicaid expansion increases cancer clinical trial participation

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Immunotherapy combination extends progression-free survival in patients with melanoma

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Only a small percentage of older adults with early Alzheimer's eligible for new treatments

Some early-stage, low-risk breast cancer patients may not need radiotherapy after surgery

Pig kidney xenotransplantation continues to function well after 32 days

Study highlights the delay in advanced stroke care and treatments

Natural bioactive molecules can relieve cold and flu symptoms

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Proton radiotherapy used for the first time in Switzerland to treat esophageal tumor

Study discovers new mechanism for deadly tumor switch in prostate cancer

Intensive lifestyle intervention linked to increased employment for people with type 2 diabetes

Study examines the relationship between consumption of fatty acids and diabetic retinopathy

A blood test that screens for cancer: Does it do more harm than good?

Illustrating the safety of a new drug treatment designed for spinal cord injury

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

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