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Antibiotic use linked to higher risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Menopausal hormone therapy taken soon after menopause may benefit the brain

Taking menopausal hormone therapy soon after menopause to relieve symptoms may also benefit the brain, according to a study published in the March 21, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

22 Mar 2018

Maternal intake of DHA supplement linked to higher fat-free body mass in children

University of Kansas researchers have reported that pregnant women who consumed a supplement of DHA (docosahexaenoic acid), a nutrient added to U.S. infant formulas since 2002, tend to have children with higher fat-free body mass at 5 years old.

21 Mar 2018

Diabetes medication reduces chance of late miscarriage, premature birth among women with PCOS

The oral diabetes medication metformin seems to reduce the chance of a late miscarriage and premature birth among women with polycystic ovary syndrome but does not affect their rate of developing gestational diabetes, a multicenter study finds.

20 Mar 2018

LSD reduces 'sense of self' - research

Dr Albert Hofmann, a Swiss chemist, first found the effects of LSD or lysergic acid diethylamide or “acid” on the psyche. It has been 75 years since his invention. Now new research finds deeper understanding of how this psychedelic chemical alters the perception and affects the brain.

19 Mar 2018

Oral micronized progesterone may reduce hot flashes, night sweats in perimenopausal women

Oral micronized progesterone may diminish hot flashes and night sweats in perimenopausal women, new research from Canada reports.

19 Mar 2018

Hormone imbalance may be reason for higher diabetes rates among men with insufficient sleep

Studies have found an association between insufficient sleep and the development of insulin resistance, one of the factors that cause type 2 diabetes, and now researchers have discovered a biological reason for this relationship, at least in men: an imbalance between their testosterone and cortisol hormones.

19 Mar 2018

New diabetes drug may help obese people shed body weight

A compound that mimics a naturally occurring hormone that regulates appetite may help people who have obesity but not diabetes to lose weight, a new study suggests.

19 Mar 2018

Male birth control pill taken once a day shows success

A new birth control pill for men with a hormonal component has shown efficacy and safety in preventing pregnancies when used once daily for a month. The study was presented yesterday (18th of March 2018) at the ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Illinois.

19 Mar 2018

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Once funding is obtained, researchers can perform a clinical trial to test the efficacy of transplanting bone marrow cells into muscles to stop deterioration caused by the illness. The method has already yielded positive results on mice.

16 Mar 2018

Novel use for drug shows promise as effective treatment for postoperative nausea and vomiting

An innovative use for a known drug is showing promise as an effective treatment for preventing postoperative nausea and vomiting, suggests a study published today in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists.

14 Mar 2018

New study provides clues about how ADHD drugs affect healthy brains

A new study shows that healthy people who take attention deficit hyperactivity disorder (ADHD) drugs experience a surge in the neurotransmitter glutamate in key parts of the brain. And that increase in glutamate is associated with subsequent changes in positive emotion.

14 Mar 2018

New class of menopause drugs provides beneficial effects in just three days

A new class of experimental drugs reduces hot flushes in menopausal women by almost three-quarters in just three days.

14 Mar 2018

Perioperative beta blockers could increase deaths and strokes one year after surgery

During the 12 months after undergoing noncardiac surgery, patients with or at risk for heart disease who were treated with the beta blocker metoprolol for 30 days were less likely than patients who received a placebo to have a heart attack, but more likely to die or have a stroke, according to research presented at the American College of Cardiology's 67th Annual Scientific Session.

13 Mar 2018

Patients given six-month dual antiplatelet therapy have increased heart attack risk

The combined rate of death from any cause, heart attack or stroke within 18 months was not significantly different in patients with acute coronary syndrome who were randomly assigned to receive dual antiplatelet therapy for either six months or at least 12 months after receiving a drug-eluting stent.

13 Mar 2018

Blood-thinning drug mitigates risk of complications, death after non-cardiac surgery

Researchers in Hamilton have discovered that a blood-thinning drug, dabigatran, significantly reduces the risk of death, heart attack, stroke, and other heart or blood-vessel complications in patients who have a heart injury following major, non-cardiac surgery.

12 Mar 2018

Statins may provide benefits to patients who underwent percutaneous coronary intervention

Getting a large dose of a statin did not have an impact on major adverse cardiac events among a broad population of patients slated to undergo percutaneous coronary intervention, a procedure to clear blocked arteries, in a trial being presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Inhaled therapy for heart failure fails to meet either primary or secondary endpoints

Four weeks of treatment with a novel inhaled medication failed to improve exercise capacity, daily activity levels, severity of symptoms or quality of life in patients with a type of heart failure for which no effective treatment options currently exist, according to research presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Among patients with persistently high cholesterol despite high-intensity statin therapy, the proprotein convertase subtilisin-kexin 9 (PCSK9) inhibitor alirocumab reduced rates of major adverse cardiovascular events by 15 percent compared with placebo, in a study presented at the American College of Cardiology's 67th Annual Scientific Session.

12 Mar 2018

Placebo News and Research

Antibiotic use linked to higher risk of severe viral disease in mice

Antibody sweeps away Alzheimer's plaques in mice

Menopausal hormone therapy taken soon after menopause may benefit the brain

Maternal intake of DHA supplement linked to higher fat-free body mass in children

Diabetes medication reduces chance of late miscarriage, premature birth among women with PCOS

LSD reduces 'sense of self' - research

Oral micronized progesterone may reduce hot flashes, night sweats in perimenopausal women

Hormone imbalance may be reason for higher diabetes rates among men with insufficient sleep

New diabetes drug may help obese people shed body weight

Male birth control pill taken once a day shows success

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Novel use for drug shows promise as effective treatment for postoperative nausea and vomiting

New study provides clues about how ADHD drugs affect healthy brains

New class of menopause drugs provides beneficial effects in just three days

Perioperative beta blockers could increase deaths and strokes one year after surgery

Patients given six-month dual antiplatelet therapy have increased heart attack risk

Blood-thinning drug mitigates risk of complications, death after non-cardiac surgery

Statins may provide benefits to patients who underwent percutaneous coronary intervention

Inhaled therapy for heart failure fails to meet either primary or secondary endpoints

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

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