Genome News and Research

RSS

The vaginal microbiome through the lens of systems biology

A new paper recently published online in Trends in Microbiology journal reviews the systems biology approach to explore the vaginal microbiome (VMB), helping to understand its composition and function and the mechanisms by which it interacts with the host.

22 Nov 2022

New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Researchers identify a novel RSV variant associated with prolonged infection

Researchers examine pathogen or host genetic risk factors for RSV infection, as well as whether certain viral variants are associated with prolonged infection.

20 Nov 2022

UH researcher aims to find causal pathways to developmental disabilities among children in rural Zambia

Of the 2.6 billion children in the world, 11% or 291.2 million are estimated to have one of four developmental disabilities – epilepsy, intellectual disability, vision loss and hearing loss. Ninety-five percent of these children live in low- and middle-income countries, predominantly in sub-Saharan Africa and South Asia, according to recent estimates.

20 Nov 2022

New AI blood testing technology detects more than 80% of liver cancers

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.

20 Nov 2022

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Researchers detected a swine influenza A virus (IAV)-infected patient in routine surveillance at the National Influenza Center in Denmark. The detected influenza variant appeared distinct from any variant found previously in Denmark.

18 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Scientists have developed a clinical WGS workflow that can detect transmission events of a pathogen before they become dominant.

18 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

Researchers validated monkeypox virus (MPXV) quantitative polymerase chain reaction (qPCR) assays.

17 Nov 2022

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

The SARS-CoV-2 Deltacron does not exhibit higher transmissibility or immune evasion than the Omicron BA.1 variant.

16 Nov 2022

Whole genome sequencing could help to reduce the spread of drug-resistant bacteria in hospitals

The spread of antibiotic-resistant bacteria in hospitals could be greatly reduced thanks to research by The University of Queensland and Queensland Health.

16 Nov 2022

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

16 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

A collaborative study led by the University of Oxford as part of the UK's 100,000 Genomes Project, published in Nature Genetics today, has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukemia (CLL) and associated these with clinical outcomes.

16 Nov 2022

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

Genome News and Research

The vaginal microbiome through the lens of systems biology

New studies improve understanding of the genetic factors that protect people against COVID-19

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Study suggests bats are an underrecognized arenavirus reservoir

MIT researchers develop new technique for genome-wide studies of the liver

Rutgers scientists develop new approach to effectively shut down viral infections

Researchers identify a novel RSV variant associated with prolonged infection

UH researcher aims to find causal pathways to developmental disabilities among children in rural Zambia

New AI blood testing technology detects more than 80% of liver cancers

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Scientists explore bat sarbecovirus isolation in Japan

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

Whole genome sequencing could help to reduce the spread of drug-resistant bacteria in hospitals

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Whole-genome sequencing reveals five new subgroups of chronic lymphocytic leukemia

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News