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Leading cancer researchers address eight 'big questions'

Leading cancer researchers address eight of the "big questions" facing the field as part of the inaugural issue of Trends in Cancer, published by Cell Press.

30 Sep 2015

New report implicates five genetic regions that play major roles in CF disease severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could lead to new therapies.

29 Sep 2015

GENALICE announces global launch date of new analysis module for genomics researchers

Today GENALICE announced the global launch date of Population Calling, a new analysis module and part of their GENALICE MAP Next-Generation Sequencing Data Analysis Suite.

29 Sep 2015

Study may lead to new insights on use of aspirin in GI cancer

Aspirin improves survival in patients with tumours situated throughout the gastrointestinal (GI) tract, results from a large study in The Netherlands show. This is the first time that survival data from patients with tumours in different GI locations have been analysed at the same time; previously, only one type of cancer, usually colorectal, was studied.

28 Sep 2015

Genetic mutations predict breast cancer relapse

A large genetics study has identified genetic mutations specific to recurrent breast cancer cells. Screening for these mutations in breast cancer tumours could therefore allow doctors to identify patients most at risk of their cancer returning. The relevant genes can then be targeted to prevent recurrence of the cancer.

27 Sep 2015

Comprehensive collection of human genomic variants now available in Kaviar database

The Institute for Systems Biology (ISB) and the Inova Translational Medicine Institute (ITMI) announced today a new release of Kaviar, the most comprehensive collection of human genomic variants currently available to the public.

26 Sep 2015

Scientists identify different CRISPR system with potential to advance genetic engineering

A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome engineering.

26 Sep 2015

Matchmaker Exchange platform launched for uncovering rare disease genes

In a special issue of Human Mutation, a team including investigators at Brigham and Women's Hospital has announced the launch of the Matchmaker Exchange - a way for the rare disease community to share information and find new connections. Matchmaker Exchange connects databases of genetic information and symptoms that physicians and investigators can "match" with a patient's rare disease.

25 Sep 2015

Researchers to use big data to improve classification of mood disorders

Mood disorders like depression are common among U.S. adults. Still, such disorders remain challenging for clinicians to diagnose and treat effectively.

24 Sep 2015

Research suggests potential drug targets to stop cancer spread

It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for years, only to trigger a recurrence decades after the primary tumor is removed.

24 Sep 2015

Mayo Clinic's Gianrico Farrugia highlights five areas that may impact patient care

How is individualized medicine working? Let us count the ways. That's just what Mayo Clinic Vice President Gianrico Farrugia, M.D., did this morning in his opening keynote at the 4th annual Individualizing Medicine Conference. The core of his talk highlighted five areas in which the knowledge and know-how from the human genome will be most impactful in patient care, not just at Mayo Clinic, but anywhere in the nation and globally.

23 Sep 2015

NYSCF, Q-State partner to advance precision medicine for nervous system disorders

The New York Stem Cell Foundation and Q-State Biosciences are partnering in a joint research collaboration to advance patient care for nervous system disorders through precision medicine. Through this collaboration, both organizations will further advance their respective technologies, while exploring how their proprietary research platforms might provide synergies in the process of developing novel therapeutics and companion diagnostics.

21 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

Specific biomarker predicts which HER2-negative breast cancer patients respond to targeted therapy

A multicenter team led by Case Western Reserve has demonstrated that brief exposure to a targeted therapy can tell doctors which HER2-negative patients will respond — and which should switch to another kind of treatment.

18 Sep 2015

WuXi NextCODE, CHFU partner to advance precision medicine in China

WuXi NextCODE, a precision medicine company using the genome to improve health worldwide, and the Children's Hospital of Fudan University, based in Shanghai and serving 2.3 million patients nationwide per year, today announced the signing of a landmark agreement for advancing precision medicine in China.

16 Sep 2015

Articles sponsored by NIH Health Care Systems Research Collaboratory provide new standpoint on clinical research

A special series of articles addressing the ethical and regulatory challenges to pragmatic clinical trials appears this week on the website of the journal Clinical Trials.

16 Sep 2015

UCSF receives $5 million grant to create online database on all types of cancer

UC San Francisco has received a National Cancer Institute grant of $5 million over the next five years to lead a massive effort to integrate the data from all experimental models across all types of cancer.

16 Sep 2015

Qualitative RPCI study evaluates attitudes toward smoking cessation in Northern Appalachia

Significant differences in attitudes toward smoking cessation are reported between two generations of smokers in Northern Appalachia in new research from Roswell Park Cancer Institute.

14 Sep 2015

Genetics and race influence patients' response to anticancer drug treatments

A new study published in Pharmacogenomics suggests that a person's response to anticancer drug treatments is strongly related to their genetic ancestry. Pharmacogenomics is published by Future Science Group.

14 Sep 2015

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

St. Louis College of Pharmacy and Washington University School of Medicine in St. Louis are joining forces to find better, safer and more effective ways to use prescription medications to improve health. Researchers from the two institutions are collaborating to create the Center for Clinical Pharmacology.

14 Sep 2015

Precision Medicine News and Research

Leading cancer researchers address eight 'big questions'

New report implicates five genetic regions that play major roles in CF disease severity

GENALICE announces global launch date of new analysis module for genomics researchers

Study may lead to new insights on use of aspirin in GI cancer

Genetic mutations predict breast cancer relapse

Comprehensive collection of human genomic variants now available in Kaviar database

Scientists identify different CRISPR system with potential to advance genetic engineering

Matchmaker Exchange platform launched for uncovering rare disease genes

Researchers to use big data to improve classification of mood disorders

Research suggests potential drug targets to stop cancer spread

Mayo Clinic's Gianrico Farrugia highlights five areas that may impact patient care

NYSCF, Q-State partner to advance precision medicine for nervous system disorders

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Specific biomarker predicts which HER2-negative breast cancer patients respond to targeted therapy

WuXi NextCODE, CHFU partner to advance precision medicine in China

Articles sponsored by NIH Health Care Systems Research Collaboratory provide new standpoint on clinical research

UCSF receives $5 million grant to create online database on all types of cancer

Qualitative RPCI study evaluates attitudes toward smoking cessation in Northern Appalachia

Genetics and race influence patients' response to anticancer drug treatments

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

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