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Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Sacubitril/valsartan and dapagliflozin combination exerts better effects in patients with diabetes and STEMI

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at observing the clinical effects of sacubitril/valsartan combined with dapagliflozin on cardiac function and ventricular remodeling in patients with type 2 diabetes and ST-segment elevation myocardial infarction (STEMI).

26 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Do glucose-lowering medications have different effects on kidney outcomes?

Researchers evaluated the kidney outcomes in individuals with type 2 diabetes.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

New review unravels phthalates’ role in heart disease

Researchers review existing data on the impact of phthalate exposure on cardiovascular health.

25 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant.

25 May 2023

Biological abnormality makes some infants vulnerable to sudden death

Sudden infant death syndrome is a case where the death of an apparently healthy infant before their first birthday remains unexplained even after thorough investigation. Death generally seems to occur when infants are sleeping.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Researchers assessed the safety and efficacy of danuglipron in type 2 diabetes (T2D) patients.

24 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Chronic obstructive pulmonary disease patients newly prescribed non-benzodiazepine benzodiazepine receptor agonists (NBZRAs) such as zolpidem (Ambien, Intermezzo and other brands), a class of hypnotic drugs prescribed for insomnia, did not have an increased risk of exacerbations requiring hospitalizations or of death than those prescribed other types of hypnotics, according to research published at the ATS 2023 International Conference.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

To commemorate World Schizophrenia Awareness Day, we spoke to three researchers from the Queensland Brain Institiute about their research, and why it is so important to raise awareness around Schizophrenia

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

Receptor News and Research

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Sacubitril/valsartan and dapagliflozin combination exerts better effects in patients with diabetes and STEMI

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Do glucose-lowering medications have different effects on kidney outcomes?

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

New review unravels phthalates’ role in heart disease

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

Biological abnormality makes some infants vulnerable to sudden death

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

The adaptive immunity of human endemic viruses

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

What is the efficacy, safety, and tolerability of novel danuglipron in adults with type two diabetes?

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Hypnotic drug class may not have increased the risk of exacerbations and death among COPD patients

Looking at cancer drugs to help put the brakes on classic indicators of aging

The antimicrobial potential of nanoparticles

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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