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Experimental drug suppresses new defective PTEN cancer pathway, study finds

A collaboration between Saïd M. Sebti, Ph.D., chair of Moffitt Cancer Center's Drug Discovery Department, and Michele Pagano, M.D., chair of the Department of Biochemistry and Molecular Pharmacology at New York University's Langone Medical Center, led to the publication of an important study in the latest issue of Nature.

14 Jun 2017

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Saint Louis University researchers report in Molecular Metabolism new findings that the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries.

14 Jun 2017

Newly discovered natural antibiotic could help fight against drug-resistant TB

The number of drug-resistant tuberculosis (TB) cases is rising globally. But a newly discovered natural antibiotic -- produced by bacteria from the lung infection in a cystic fibrosis patient -- could help fight these infections.

14 Jun 2017

Study shows how RNA splicing errors may trigger development of ALS, FTD

The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.

14 Jun 2017

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

A study published in the journal Cell on June 13 has found that a class of small molecules can successfully penetrate and darken human skin samples. The drug developed in the laboratory by researchers in Boston also generates protective tans in red-haired mice.

14 Jun 2017

Research may lead to more accurate and reliable diagnostic test for autoimmune disease

In autoimmune diseases, the immune system wrongly identifies its "enemy", and produces antibodies that attack the patient's own cells.

14 Jun 2017

Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

Cigarette smoking causes diverse harm that extends way beyond the lungs

Warning: Cigarette smoking presents far more health hazards than you probably realize.

14 Jun 2017

TempTraq can detect rise in body temperature earlier than current SOC method, study shows

A University Hospitals Seidman Cancer Center study shows TempTraq, a patented, wearable, Bluetooth continuous temperature monitor in the form of a soft, comfortable patch, can detect a rise in body temperature up to 180 minutes earlier, in a majority of patient cases, than the current standard-of-care method.

14 Jun 2017

UAB researchers demonstrate persistence of donor microbes in recipients after fecal transplant

University of Alabama at Birmingham researchers have made the first direct demonstration that fecal donor microbes remained in recipients for months or years after a transplant to treat the diarrhea and colitis caused by recurrent Clostridium difficile infections -- a serious and stubborn cause of diarrhea after an antibiotic treatment for some other illness.

14 Jun 2017

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina in the May 19, 2017 issue of Scientific Reports.

14 Jun 2017

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Researchers in the University of Maryland Fischell Department of Bioengineering (BIOE) Jewell Laboratory are using quantum dots - tiny semiconductor particles commonly used in nanotechnology - to decipher the features needed to design specific and effective therapies for multiple sclerosis (MS) and other autoimmune diseases.

14 Jun 2017

B Cell News and Research

Experimental drug suppresses new defective PTEN cancer pathway, study finds

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Newly discovered natural antibiotic could help fight against drug-resistant TB

Study shows how RNA splicing errors may trigger development of ALS, FTD

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

Research may lead to more accurate and reliable diagnostic test for autoimmune disease

Findings may contribute to better understanding of aging and cancer development

Cigarette smoking causes diverse harm that extends way beyond the lungs

TempTraq can detect rise in body temperature earlier than current SOC method, study shows

UAB researchers demonstrate persistence of donor microbes in recipients after fecal transplant

Study emphasizes importance of molecule in maintaining balanced immune system in the gut

Researchers use quantum dots to decipher design features for new therapies aimed at MS

New research uncovers subcellular-level changes in the brain after concussion

UNC study uncovers crucial function of key enzyme found in virtually all organisms

Antibody-based theranostic agent shows promise for identifying and treating pancreatic tumors

Cornell researchers unravel E. coli bacteria's defense secret

Researchers identify key Lassa virus structure using powerful Argonne X-rays

Melbourne study offers hope for better lung cancer treatment

Study examines how sex alters time-course of inflammation in the brain after TBI

Study uncovers new genetic markers linked to testicular germ cell tumors

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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