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New therapeutic approach shows promise for pediatric high-grade gliomas

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options.

14 Mar 2025

CityUHK leads groundbreaking project to develop new platform for early cancer detection

Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods.

13 Mar 2025

Study shows impact of statins and aspirin on muscle health in smokers

For current and former smokers, statins may reduce the amount of chest muscle loss, while aspirin may contribute to increased chest muscle loss, according to a new study.

13 Mar 2025

Special class of RNA molecules may provide a new target to treat gastric cancer

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer-among the world's deadliest forms of the disease.

13 Mar 2025

Firefighting chemicals leave brain cancer-linked mutations, study shows

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting occupational risk. The study highlights a clear link between firefighting, chemical exposure, and brain cancer mutations.

13 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

Finnish study reveals complex link between physical activity and longevity

Physical activity is seen as a way to extend the human lifespan, but Finnish twin studies found the benefits of physical activity for longevity may not be as straightforward as has been previously thought.

13 Mar 2025

CRISPR technologies paving the way for advances in regenerative medicine

A recent review published in the journal Engineering delves into the significant advancements and potential of CRISPR technologies in the field of regenerative medicine.

13 Mar 2025

Impact of excessive alcohol consumption on digestive health

Excessive alcohol consumption is a significant public health concern, responsible for approximately 6% of all deaths and contributing to 5.1% of the global disease burden.

12 Mar 2025

New technique effectively identifies aggressive medulloblastoma

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma-the most common type of malignant brain tumour in children-and potentially sparing young patients from unnecessary treatments and their harmful long-term side effects.

12 Mar 2025

Developing heart cells use "speed dating" to find the right match

In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing with the wrong cell could mean the difference between a beating heart and one that falters.

12 Mar 2025

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases

Scientists identified 195 genetic risk loci across 42 female reproductive health conditions, revealing shared genetic pathways and developing a polygenic risk score for intrahepatic cholestasis of pregnancy (ICP). These findings pave the way for personalized reproductive healthcare and targeted treatments based on genetic risk.

12 Mar 2025

Examining skin cancer risk perceptions and reported sunburns among U.S. adults

Skin cancer is the most common cancer in the United States and a significant health issue, with millions of non-melanoma cases and tens of thousands of melanomas diagnosed annually. Furthermore, treating skin cancer costs the U.S. approximately $8.9 billion annually.

12 Mar 2025

Glycerol in slush ice drinks can make children sick

Slush ice drinks made with glycerol have been found to make children sick. Doctors and medical scientists in Ireland and the UK investigated following reported sickness connected with the icy refreshments.

12 Mar 2025

People from families with exceptional longevity have lower risk of peripheral artery disease

A new research paper was published in Aging (Aging-US) on February 25, 2025, Volume 17, Issue 2, titled "Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study."

12 Mar 2025

Limiting TV time may reduce heart disease risk for people with genetic risk for diabetes

Watching no more than one hour of TV a day may lower the risk of heart attack, stroke and other blood vessel diseases among people with varying levels of genetic risk for Type 2 diabetes, including high genetic risk, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

12 Mar 2025

Study identifies genetic changes in blood stem cells of frequent blood donors

Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells.

11 Mar 2025

Regulating cell acidity could transform autoimmune disease treatments

What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients' cells? Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein's role in helping another protein control cell acidity, according to new research published in Cell by a team from the Perelman School of Medicine at the University of Pennsylvania.

11 Mar 2025

Environmental factors and genes play key role in cancer development

A new editorial was published in Oncotarget, Volume 16, on March 10, 2025, titled "EXPOSOMES and GENES: The duo influencing CANCER initiation and progression."

11 Mar 2025

Arthritis and COPD together raise mortality risk

People with chronic obstructive pulmonary disease (COPD) and arthritis have a higher risk of death than people with arthritis who do not have COPD, according to a new study.

11 Mar 2025