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Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

Approval for the IMAGINE trial was granted by the Austin Health Research Ethics Committee in November 2011, with the first patients dosed in March the following year. However, well before the trial was approved, PBT2 had already shown promise in significantly changing Abeta levels in spinal fluid while improving cognition in a previous 12-week trial conducted in 2006.

28 Aug 2013

Study paves way for understanding the crucial role of lncRNA in human neurons

Scientists at A*STAR's Genome Institute of Singapore have discovered an unusual gene that controls the generation of neurons. This important finding, which is crucial in understanding serious diseases of the brain such as Alzheimer's disease, was reported in the 8th August 2013 issue of the prestigious scientific journal, Molecular Cell.

28 Aug 2013

Brain Study Suggests New Way To Treat Anxiety

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22 Aug 2013

Research findings may lead to treatments for disorders triggered by circadian clock dysfunction

Overnight flights across the Atlantic, graveyard shifts, stress-induced insomnia are all prime culprits in keeping us from getting a good night's sleep. Thanks to new research from McGill University and Concordia University, however, these common sleep disturbances may one day be put to bed.

22 Aug 2013

Medical investigators discover new aspect of gene-splicing process that produces mRNA

A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his team from the Perelman School of Medicine at the University of Pennsylvania, discovered an entirely new aspect of the gene-splicing process that produces messenger RNA (mRNA).

22 Aug 2013

Research reveals that brain circuits can help reduce anxiety disorders

Anxiety disorders, which include posttraumatic stress disorder, social phobias and obsessive-compulsive disorder, affect 40 million American adults in a given year. Currently available treatments, such as antianxiety drugs, are not always effective and have unwanted side effects.

22 Aug 2013

Psychotic symptoms in people with schizophrenia caused by faulty 'switch' within brain

Scientists at The University of Nottingham have shown that psychotic symptoms experienced by people with schizophrenia could be caused by a faulty 'switch' within the brain.

22 Aug 2013

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

A new publication in the top-ranked journal Neuron sheds new light onto the unknown processes on how the brain integrates the inputs from the different senses in the complex circuits formed by molecularly distinct types of nerve cells. The work was led by new Ume- University associate professor Paolo Medini.

21 Aug 2013

Researchers create mouse models to advance the study of unusual deadly diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases.

20 Aug 2013

Kinetin stops the effects of Parkinson's disease on brain cells, say scientists

The active ingredient in an over-the-counter skin cream might do more than prevent wrinkles. Scientists have discovered that the drug, called kinetin, also slows or stops the effects of Parkinson's disease on brain cells.

16 Aug 2013

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

University of Arizona scientists have discovered an unknown mechanism that establishes polarity in developing nerve cells. Understanding how nerve cells make connections is an important step in developing cures for nerve damage resulting from spinal cord injuries or neurodegenerative diseases such as Alzheimer's.

16 Aug 2013

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

CHD5 has previously been proposed as a tumour suppressor, acting as a brake that prevents healthy cells from developing into cancer cells. But the part played by the protein in healthy tissue, and whether this role is important for its ability to counter tumour growth, has remained largely uncharted.

14 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Research findings offer clues to the origin of retinal disorders later in life

Scientists are developing a clearer picture of how visual systems develop in mammals. The findings offer important clues to the origin of retinal disorders later in life.

9 Aug 2013

UCLA researchers invent research maps to help neuroscientists choose what to study next

Before the digital age, neuroscientists got their information in the library like the rest of us. But the field's explosion has created nearly 2 million papers -- more data than any researcher can read and absorb in a lifetime.

8 Aug 2013

TSRI scientists decode important molecular signal that guides development of neocortex

Scientists at The Scripps Research Institute have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex. The largest and most recently evolved region of the brain, the neocortex is particularly well developed in humans and is responsible for sensory processing, long-term memory, reasoning, complex muscle actions, consciousness and other functions.

8 Aug 2013

Wiring diagram of retinal neurons: The first step toward mapping the human brain

The human brain has 100 billion neurons, connected to each other in networks that allow us to interpret the world around us, plan for the future, and control our actions and movements. MIT neuroscientist Sebastian Seung wants to map those networks, creating a wiring diagram of the brain that could help scientists learn how we each become our unique selves.

8 Aug 2013

Brain tumor cells in arrested development contribute to cell variety that protects cancer

A program that pushes immature cells to grow up and fulfill their destiny as useful, dedicated cells is short-circuited in the most common and deadly form of brain tumor, scientists at The University of Texas MD Anderson Cancer Center report this week in the Early Edition of the Proceedings of the National Academy of Sciences.

8 Aug 2013

Scientists identify important molecular signal that guides development of brain

Scientists at The Scripps Research Institute (TSRI) have decoded an important molecular signal that guides the development of a key region of the brain known as the neocortex.

8 Aug 2013

Study shows role of love hormone in promoting social and parental bonding

In a loud, crowded restaurant, having the ability to focus on the people and conversation at your own table is critical. Nerve cells in the brain face similar challenges in separating wanted messages from background chatter.

6 Aug 2013

Neuron News and Research

Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

Study paves way for understanding the crucial role of lncRNA in human neurons

Brain Study Suggests New Way To Treat Anxiety

Research findings may lead to treatments for disorders triggered by circadian clock dysfunction

Medical investigators discover new aspect of gene-splicing process that produces mRNA

Research reveals that brain circuits can help reduce anxiety disorders

Psychotic symptoms in people with schizophrenia caused by faulty 'switch' within brain

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

Researchers create mouse models to advance the study of unusual deadly diseases

Kinetin stops the effects of Parkinson's disease on brain cells, say scientists

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Research findings offer clues to the origin of retinal disorders later in life

UCLA researchers invent research maps to help neuroscientists choose what to study next

TSRI scientists decode important molecular signal that guides development of neocortex

Wiring diagram of retinal neurons: The first step toward mapping the human brain

Brain tumor cells in arrested development contribute to cell variety that protects cancer

Scientists identify important molecular signal that guides development of brain

Study shows role of love hormone in promoting social and parental bonding

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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