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New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

The German Research Foundation (DFG) has approved the establishment and funding of the Collaborative Research Center/Transregio (CRC/TRR) 355 "Heterogeneity and functional specialization of regulatory T cells in distinct microenvironments".

2 Dec 2022

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

The German Research Foundation (DFG) announced the prolongation of the Collaborative Research Center (CRC) 1361: "Regulation of DNA Repair and Genome Stability" for an additional four years.

2 Dec 2022

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

Study suggests new strategies for making cartilage cells

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and temporomandibular joint disorder (TMJ), affect 350 million people in the world and cost the US public health system more than $303 billion every year.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T) – is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times.

30 Nov 2022

New EU-funded project aims to find better strategies to protect vulnerable people from mental illness

To improve understanding of mental health, today's symptom-based diagnoses need to be complemented with biological criteria accounting for differences between individuals and the sexes.

30 Nov 2022

The evolutionary trajectories and mechanisms driving the emergence of post-Omicron SARS-CoV-2 lineages

Researchers summarized the mechanisms through which the SARS-CoV-2 new Omicron sublineages are evolving.

30 Nov 2022

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types.

29 Nov 2022

What genes are associated with asthma exacerbations?

In a new study, researchers reviewed the genomics, transcriptomics, and epigenetics of asthma exacerbations (AEs).

29 Nov 2022

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Researchers investigate the genetic, immunological, and evolutionary factors that determine the vast variability observed in clinical manifestations of COVID-19.

28 Nov 2022

Rogue killer T cells associated with leukemia drive autoimmune diseases

Gene variants associated with leukemia can produce 'rogue' immune cells that drive autoimmune diseases, according to a new study from the Garvan Institute of Medical Research.

28 Nov 2022

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

Two studies emphasize the need for ethnically diverse prostate cancer genetic testing

More than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the disease remain unexplored for the majority of patients around the world.

28 Nov 2022

Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine.

25 Nov 2022

Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

A study has employed Bacter to identify recombination events with the RBD regions of the Sarbecovirus genome.

25 Nov 2022

BW.1- a new Omicron subvariant that escapes immunity

Researchers reports the presence of mutations that aid in immune escape in the BW.1 Omicron subvariant.

25 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

Researchers from the Quadram Institute and the University of East Anglia have uncovered how resistance has helped drive the emergence of dominant strains of Salmonella.

24 Nov 2022

Genome News and Research

New Collaborative Research Center investigates how Treg cells influence immunological and tissue-specific diseases

CRC 1361 at JGU continues to achieve excellence in DNA repair and genome stability research

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

Study suggests new strategies for making cartilage cells

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

New EU-funded project aims to find better strategies to protect vulnerable people from mental illness

The evolutionary trajectories and mechanisms driving the emergence of post-Omicron SARS-CoV-2 lineages

AI tool can reliably classify difficult-to-diagnose nasal cavity tumors

What genes are associated with asthma exacerbations?

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Rogue killer T cells associated with leukemia drive autoimmune diseases

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Two studies emphasize the need for ethnically diverse prostate cancer genetic testing

Researchers discover a new function of CRISPR/Cas9 gene scissors

Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

BW.1- a new Omicron subvariant that escapes immunity

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Study provides a key link between the social environment and healthy brains

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

Genetics & Genomics - Second Edition eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

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