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Older adults from disadvantaged communities less likely to attend cardiac rehabilitation after heart procedures

Older adults who live in disadvantaged communities are less likely to attend cardiac rehabilitation after common heart procedures, a Michigan Medicine-led study finds.

24 Oct 2023

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

Necrotizing enterocolitis (NEC) is a debilitating and deadly condition that affects infants who were born preterm.

24 Oct 2023

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorectal cancer, patients who also had diabetes - particularly those with diabetic complications - faced a higher risk of dying early.

24 Oct 2023

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to results of a Phase III trial reported by researchers at The University of Texas MD Anderson Cancer Center.

24 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.

24 Oct 2023

New method provides valuable insights into the brain's noradrenaline system

An international team of researchers has provided valuable insights into the brain's noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety.

24 Oct 2023

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells.

24 Oct 2023

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Integrated liquid-biopsy proteomics with single-cell transcriptomics from ocular cell types.

24 Oct 2023

Researchers receive $3.6 million to test novel diagnosis and treatment combination for diabetic neuropathy

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24 Oct 2023

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

The use of resistant potato starch (RPS), to modify gut microbial metabolism.

24 Oct 2023

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Patients with a dysfunctional aortic heart valve who received a new, prosthetic valve through a minimally invasive procedure had similar outcomes at five years as those who underwent open-heart surgery, a new study shows.

24 Oct 2023

Quick genetic test offers hope for sick, undiagnosed kids. but few insurers offer to pay.

Just 48 hours after her birth in a Seattle-area hospital in 2021, Layla Babayev was undergoing surgery for a bowel obstruction.

23 Oct 2023

New insights into why obesity puts individuals at risk for severe influenza

The mechanisms underpinning severe cases of influenza among the obese population.

23 Oct 2023

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

A clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improved survival in patients with an advanced type of bladder cancer.

22 Oct 2023

Perioperative immunotherapy improves event-free survival in resectable early-stage lung cancer

Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy – given before and after surgery – significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer (NSCLC).

22 Oct 2023

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

The INTERLACE phase III trial, funded by Cancer Research UK and UCL Cancer Trials Centre, assessed whether a short course of induction chemotherapy (IC) prior to chemoradiation (CRT) could reduce the rate of relapse and death among patients with locally advanced cervical cancer.

22 Oct 2023

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

22 Oct 2023

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery.

22 Oct 2023

Pediatric trauma increased among socioeconomically disadvantaged children during the pandemic

Injuries from gunshots and motor vehicle crashes increased among children and teenagers during the COVID-19 pandemic, especially those residing in socioeconomically disadvantaged neighborhoods, according to new research being presented at the American College of Surgeons (ACS) Clinical Congress 2023.

20 Oct 2023

Surgery News and Research

Older adults from disadvantaged communities less likely to attend cardiac rehabilitation after heart procedures

Biofilm probiotic effective in preventing necrotizing enterocolitis in piglet model

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

Researchers discover new way to trigger programmed cell death in cancer cells

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

New method provides valuable insights into the brain's noradrenaline system

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Researchers receive $3.6 million to test novel diagnosis and treatment combination for diabetic neuropathy

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Quick genetic test offers hope for sick, undiagnosed kids. but few insurers offer to pay.

New insights into why obesity puts individuals at risk for severe influenza

Chemotherapy plus immunotherapy improves survival in patients with metastatic urothelial cancer

Perioperative immunotherapy improves event-free survival in resectable early-stage lung cancer

Short course of induction chemotherapy can reduce cervical cancer relapse and death by 35%

Dual-action drug produces shows promising results in neuroendocrine tumor trial

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

Pediatric trauma increased among socioeconomically disadvantaged children during the pandemic

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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