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Scientists reveal unexpected route to slow progression of diabetic kidney disease

More than 660,000 people in the United States suffer from end-stage kidney disease, which can only be treated by dialysis or kidney transplantation. Almost half of these patients develop the condition as a complication of diabetes.

25 Apr 2017

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

The bacteria residing in your digestive tract, or your gut microbiota, may play an important role in your ability to respond to chemotherapy drugs in the clinic, according to a new study by scientists at the University of Massachusetts Medical School.

25 Apr 2017

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.

25 Apr 2017

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.

24 Apr 2017

Researchers discover gene that may play role in restoring hearing after noise exposure

Researchers have discovered that a protein implicated in human longevity may also play a role in restoring hearing after noise exposure. The findings, where were published in the journal Scientific Reports, could one day provide researchers with new tools to prevent hearing loss.

24 Apr 2017

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

Cells in the brain's master circadian clock synchronize voltage rhythms despite asynchronous calcium rhythms, which might explain how a tissue-wide rhythm is maintained.

24 Apr 2017

New model for toxicity risk assessment could reduce reliance on animal testing

Traditional toxicological investigations performed on animals (in vivo) are expensive, time-consuming and may cause animal suffering.

24 Apr 2017

Researchers discover new cellular mechanism that may cause multiple sclerosis

A new study has made a major new discovery towards finding the cause of multiple sclerosis (MS), potentially paving the way for research to investigate new treatments.

24 Apr 2017

Researchers discover cancer-fighting properties in beta blockers

A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. Researchers serendipitously discovered the beta blocker's cancer-fighting properties after making an error in the lab.

24 Apr 2017

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Survey finds nearly 60% of seniors using cell phones while driving

The distracted driving habits of young drivers have received a lot of media attention, with reports of Snapchatting, tweeting, texting and other dangerous behaviors. However, there has been a lack of data on whether seniors also engage in these behaviors behind the wheel.

21 Apr 2017

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Researchers show how fish oil component helps in survival of injured retina, brain cells

A team of researchers led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has shown for the first time that NDP1, a signaling molecule made from DHA, can trigger the production of a protective protein against toxic free radicals and injury in the brain and retina.

21 Apr 2017

UCLA research overturns paradigm about how axons grow during embryonic development

New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons -- thread-like projections that connect cells in the nervous system -- grow during embryonic development.

21 Apr 2017

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

21 Apr 2017

Researchers discover how protein aggregation triggers aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation affects this genetic program and thus triggers aging.

21 Apr 2017

Hockey players with multiple concussions may have other injuries in their brains, research reveals

The relationship between head injuries suffered during contact sport and Alzheimer's disease is now being called into question thanks to research by the Sahlgrenska Academy, which has revealed that hockey players with multiple concussions probably have other injuries in their brains.

21 Apr 2017

Researchers develop new approach to protect stem cell recipients from graft-versus-host disease

Stem cell transplants can save lives, for example in patients with leukemia. However, these treatments are not free of risks. One complication that may occur is graft-versus-host disease (GVHD), basically donor-derived immune cells attacking the recipient’s body.

21 Apr 2017

Clinical Cytology Biobank chooses Micronic's storage tubes for preservation of gynaecological cell samples

To support healthcare and scientific research groups with high quality cytological cell samples, the National Clinical Cytology Biobank at the Karolinska Institute in Stockholm (Sweden) has invested in 2D coded sample storage tubes and sample handling equipment from Micronic to provide traceable, high integrity storage of its valuable gynaecological cell samples.

21 Apr 2017

Restricting amino acids in diet slows tumor growth, prolongs survival in mice

Cutting out certain amino acids – the building blocks of proteins – from the diet of mice slows tumour growth and prolongs survival, according to new research published in Nature today (Wednesday).

21 Apr 2017

B Cell News and Research

Scientists reveal unexpected route to slow progression of diabetic kidney disease

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types

Researchers discover gene that may play role in restoring hearing after noise exposure

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

New model for toxicity risk assessment could reduce reliance on animal testing

Researchers discover new cellular mechanism that may cause multiple sclerosis

Researchers discover cancer-fighting properties in beta blockers

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Survey finds nearly 60% of seniors using cell phones while driving

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Researchers show how fish oil component helps in survival of injured retina, brain cells

UCLA research overturns paradigm about how axons grow during embryonic development

Researchers use gene-editing tool to restore visual function in mouse models of retinitis pigmentosa

Researchers discover how protein aggregation triggers aging

Hockey players with multiple concussions may have other injuries in their brains, research reveals

Researchers develop new approach to protect stem cell recipients from graft-versus-host disease

Clinical Cytology Biobank chooses Micronic's storage tubes for preservation of gynaecological cell samples

Restricting amino acids in diet slows tumor growth, prolongs survival in mice

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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