B Cell News and Research

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Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.

18 Apr 2017

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

Although human population studies have linked air pollution to chronic inflammation of nasal and sinus tissues, direct biological and molecular evidence for cause and effect has been scant.

18 Apr 2017

New Virtual Microscopy Database helps educators and students zoom into the human body

A medical student in Michigan. A nursing student in Ghana. An anatomy professor in Brazil. A researcher in Australia. All need to learn -- or teach -- about the human body at the most basic level.

18 Apr 2017

Study shows how early administration of old drug reduces damage during heart attack

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have discovered a new mechanism of action of metoprolol, a drug that can reduce the damage produced during a heart attack if administered early.

18 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

Study establishes potential of BAT receptors as druggable targets for treatment of obesity, diabetes

According to research published online in The FASEB Journal, scientists have discovered a way to increase the amount of metabolism-boosting brown adipose tissue (BAT) ("good" fat) by employing two receptors on BAT cells as potential therapeutic targets.

17 Apr 2017

MIT researchers develop new technique to make high-resolution images of tissues

MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar resolution.

17 Apr 2017

Microscopic probes simplify process of measuring electrical signals in small animals

Microscopic probes developed at Rice University have simplified the process of measuring electrical activity in individual cells of small living animals. The technique allows a single animal like a worm to be tested again and again and could revolutionize data-gathering for disease characterization and drug interactions.

17 Apr 2017

ASTRO issues new clinical guideline for management of oropharyngeal cancer with radiation therapy

The American Society for Radiation Oncology today issued a new clinical guideline for the management of oropharyngeal cancer.

17 Apr 2017

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.

17 Apr 2017

Discovery of additional viral reservoir reveals new target for HIV cure research

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system.

17 Apr 2017

DeNovix pink spectrophotometer - fluorometer won by Ukraine National Acaedemy of Science

DeNovix Inc.

From DeNovix Inc. 17 Apr 2017

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Medical University of South Carolina investigators report that long-term expansion protocols for adoptive cancer immunotherapy do not compromise Th17 cells' effectiveness against large tumors, in the March 9, 2017 issue of JCI Insight.

17 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

Scientists identify gene responsible for generating key lipid in skin barrier formation

Scientists have identified the gene responsible for generating acylceramide, the key lipid in forming the skin barrier that protects us from pathogens, allergens and other harmful substances. This finding could prove crucial in developing medicines for treating atopic dermatitis and ichthyosis.

17 Apr 2017

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

A vaccine targeting cytomegalovirus (CMV) antigen pp65, combined with high-dose chemotherapy (temozolomide), improved both progression-free survival and overall survival for a small group of glioblastoma (GBM) patients.

17 Apr 2017

Thyroid cancer patients with bone metastases have worse survival, study finds

When cancer metastases, bone unwittingly offers a friendly place for tumor cell growth--only to have its hospitality betrayed by pathologic fractures, spinal cord compression, the need for bone surgery or irradiation, and an increased risk of death.

17 Apr 2017

Collaboration between Hamilton Robotics and Illumina creates noninvasive streamlined prenatal testing solution

Hamilton Robotics continues to strengthen their ongoing partnership with Illumina, Inc. through the collaborative development of the VeriSeq™ NIPT Solution for high-throughput noninvasive prenatal testing (NIPT).

From Hamilton Process Analytics 14 Apr 2017

Seeing genes inside living cells

For Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.

14 Apr 2017

Cell cultures in petri dishes open new doors to brain research

The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it - ones that could help us to understand neurodegenerative diseases like Parkinson's, for example.

13 Apr 2017

B Cell News and Research

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Air pollution may directly affect biology of upper airways to cause chronic sinus problems

New Virtual Microscopy Database helps educators and students zoom into the human body

Study shows how early administration of old drug reduces damage during heart attack

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Study establishes potential of BAT receptors as druggable targets for treatment of obesity, diabetes

MIT researchers develop new technique to make high-resolution images of tissues

Microscopic probes simplify process of measuring electrical signals in small animals

ASTRO issues new clinical guideline for management of oropharyngeal cancer with radiation therapy

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model

Discovery of additional viral reservoir reveals new target for HIV cure research

DeNovix pink spectrophotometer - fluorometer won by Ukraine National Acaedemy of Science

Th17 cell durability offers promise for next-generation adoptive cancer immunotherapy trials

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Scientists identify gene responsible for generating key lipid in skin barrier formation

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

Thyroid cancer patients with bone metastases have worse survival, study finds

Collaboration between Hamilton Robotics and Illumina creates noninvasive streamlined prenatal testing solution

Seeing genes inside living cells

Cell cultures in petri dishes open new doors to brain research

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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