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Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

A recent study assessed the mechanism by which SARS-CoV-2 Omicron and Alpha VOCs inhibit the SARS-CoV-2 spike protein and mitigate the risk of a multisystem inflammatory syndrome in children.

28 Feb 2022

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

In a recent study, researchers evaluated the effect of COVID-19 vaccines on the symptomatic prevalence of SARS-CoV-2 infections beyond the acute phase of the disease.

28 Feb 2022

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Researchers generated a panel of bnAbs against SARS-CoV, SARS-CoV-2, and its variant VOCs, including Omicron from sequentially immunized mice.

28 Feb 2022

Will Omicron BA.2 become the next dominant variant?

A new study presents a comprehensive analysis of the potential of both Omicron BA.2 and BA.3 to become the next dominant circulating SARS-CoV-2 strain.

27 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A new study discusses changes in the microbiota of various parts of the body with SARS-CoV-2 infection.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

Researchers assess the serological response to a real-world COVID-19 vaccination strategy in older individuals who resided in long-term care facilities.

24 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

MIT chemists develop a novel way to synthesize himastatin

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

24 Feb 2022

Study provides a promising new avenue for development of anti-obesity treatments

An anti-tumor drug promotes weight loss in mice at low doses by activating a natural hunger-suppressing pathway, according to a new study publishing February 24th in the open-access journal PLOS Biology by Jiang Wei Wu and colleagues at Northwest A&F University in Shaanxi, China.

24 Feb 2022

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development.

24 Feb 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Researchers investigated whether residual SARS-CoV-2 antigens and RNA are present in tissues samples of long COVID-19 patients beyond the convalescent phase of COVID-19.

24 Feb 2022

Metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 Delta, Alpha, and Omicron variants

Researchers examined how SARS-CoV-2 variants of concern differentially use an additional metalloproteinase-dependent entry pathway to enter the host cells.

24 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published today in the journal Nature Communications.

23 Feb 2022

Enzyme News and Research

Molecular insights on the possible connection of SARS-CoV-2 and nicotinic acetylcholine receptors

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Will Omicron BA.2 become the next dominant variant?

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A promising new vaccine for SARS-CoV-2 and influenza

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

Melatonin as a safe and potentially life-saving treatment for COVID-19

MIT chemists develop a novel way to synthesize himastatin

Study provides a promising new avenue for development of anti-obesity treatments

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 Delta, Alpha, and Omicron variants

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

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