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Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

New research highlights potential for emergence of new form of Ebolavirus

New research at the University of Kent has highlighted the potential for the emergence of a new form of Ebolavirus. A team from the University's School of Biosciences examined the differences between Ebolaviruses that cause severe disease in humans and the Reston virus that does not.

25 Mar 2016

Lack of UBE3A gene causes Angelman syndrome

The gene UBE3A plays a critical role in early neurological development. If UBE3A is overexpressed - or if the enzymatic function of UBE3A protein is hyperactive - autism ensues. A lack of functional UBE3A causes Angelman syndrome (AS), a neurodevelopmental disorder characterized by severe developmental delay, motor deficits, absence of speech, and, in most cases, epilepsy.

25 Mar 2016

Intake of high-protein diet during weight loss improves sleep quality in adults

Overweight and obese adults who are losing weight with a high-protein diet are more likely to sleep better, according to new research from Purdue University.

25 Mar 2016

Microneedle-embedded patch delivers cancer immunotherapy directly to melanoma

Biomedical engineering researchers at North Carolina State University and the University of North Carolina at Chapel Hill have developed a technique that uses a patch embedded with microneedles to deliver cancer immunotherapy treatment directly to the site of melanoma skin cancer. In animal studies, the technique more effectively targeted melanoma than other immunotherapy treatments.

25 Mar 2016

Study uncovers role of small RNAs in fine-tuning egg development

All multicellular organisms that reproduce sexually rely on eggs to support early life. Researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research used the tiny roundworm C. elegans as a model to better understand how eggs enable embryonic development, using only the materials already present in them.

25 Mar 2016

Researchers discover human equivalent DAMP protein in plants

A protein that signals tissue damage to the human immune system has a counterpart that plays a similar role in plants, report researchers at the Boyce Thompson Institute.

25 Mar 2016

Study shows fish oil supplements make no significant difference to muscle growth

The effect of fish oil supplements on muscle growth has been investigated by a team of Stirling academics, revealing the tablets do not give gym-goers an advantage in the weight room.

24 Mar 2016

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

A normal, predominant bacterial species of the healthy vaginal microbiota can be engineered for potential use as a novel protective agent against HIV-1 transmission in women, according to a new publication from scientists at Osel, Inc. and their collaborators.

24 Mar 2016

Wide-field imaging approach can help study underlying mechanisms of brain function

University of Oregon scientists have looked into the brains of living mice to see in real time the processing of sensory information and generation of behavioral responses.

24 Mar 2016

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

Cancer therapy is often hampered by the accumulation of fluids in and around the tumour, which is caused by leakage from the blood vessels in the tumour. Researchers at Uppsala University now show how leakage from blood vessels is regulated.

24 Mar 2016

German scientists analyse LOV proteins using neutron scattering

The internal movements of proteins can be important for their functionality; researchers are discovering more and more examples of this. Now, with the aid of neutron spectroscopy, dynamic processes have also been detected in so-called "LOV photoreceptors" by scientists from Jülich, Aachen, Dusseldorf and Garching near Munich.

24 Mar 2016

Research shows tumor suppressor protein regulates polarity genes

What does Brad Pitt have in common with a fruit fly? His Hollywood hairstyles cover a prominent cowlick - the swirl of hair that that is caused by a patterning mechanism also active in our two-winged friends -- that similarly feature "polarized" hair patterns.

24 Mar 2016

Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes.

23 Mar 2016

FEI, NovAliX to jointly provide cryo-EM-based structural analysis services for pharmaceutical and biotech industry

FEI and NovAliX, a contract research organization (CRO), announced today a strategic partnership to enable NovAliX to provide commercial cryo-electron microscopy (EM)-based structural analysis services to its customers in the pharmaceutical and biotech industry.

From Thermo Fisher Scientific – Electron Microscopy Solutions 23 Mar 2016

Liverpool researchers use JPK's NanoWizard AFM system to study biological membrane structures, protein dynamics

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of their NanoWizard ULTRA Speed AFM system at the University of Liverpool in the group of Dr Luning Liu of the Institute of Integrative Biology to study biological membrane structures and protein dynamics.

From Bruker BioAFM 23 Mar 2016

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Wellcome Trust Sanger Institute scientists show how the parasite responsible for the neglected tropical disease Black Fever (visceral leishmaniasis) can become resistant to drug treatment. Studying the whole genomes of more than 200 samples of Leishmania donovani revealed that the addition of just two bases of DNA to a gene known as LdAQP1 stops the parasite from absorbing antimonial drugs.

23 Mar 2016

SLU researchers discover compound that disrupts fibrotic process

Saint Louis University researchers have found that a type of compound that disrupts the process that causes fibrosis (scarring) in the lungs and liver also shows promise in preventing and treating fibrosis in yet another organ, the pancreas. The research was conducted in an animal model.

23 Mar 2016

Study provides better picture of molecular basis for antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics.

23 Mar 2016

Targeted therapies suppress T cell activity that could actually help fight tumors

In many cases, targeted therapies for cancer are preferred as treatments over chemotherapy and surgery because they attack and kill cancer cells with specific tumor-promoting mutations while sparing healthy, normal cells that do not express these mutations.

23 Mar 2016

G Protein News and Research

Wnt secretion inhibitors may reduce renal fibrosis

New research highlights potential for emergence of new form of Ebolavirus

Lack of UBE3A gene causes Angelman syndrome

Intake of high-protein diet during weight loss improves sleep quality in adults

Microneedle-embedded patch delivers cancer immunotherapy directly to melanoma

Study uncovers role of small RNAs in fine-tuning egg development

Researchers discover human equivalent DAMP protein in plants

Study shows fish oil supplements make no significant difference to muscle growth

Engineered vaginal Lactobacilli could reduce heterosexual HIV-1 transmission in women

Wide-field imaging approach can help study underlying mechanisms of brain function

Novel mechanism can suppress blood vessel leakage, reduce tumour spread in mice

German scientists analyse LOV proteins using neutron scattering

Research shows tumor suppressor protein regulates polarity genes

Penn neurologists uncover new genetic cause of Charcot-Marie-Tooth Disease

FEI, NovAliX to jointly provide cryo-EM-based structural analysis services for pharmaceutical and biotech industry

Liverpool researchers use JPK's NanoWizard AFM system to study biological membrane structures, protein dynamics

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

SLU researchers discover compound that disrupts fibrotic process

Study provides better picture of molecular basis for antibiotic resistance

Targeted therapies suppress T cell activity that could actually help fight tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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