Pathogen News and Research

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Raw pet food not considered as significant source of infections

An extensive international survey conducted at the University of Helsinki indicates that pet owners do not consider raw food to considerably increase infection risk in their household.

7 Sep 2019

Scientists reveal how typhoid toxin works to accelerate aging of cells

Scientists have revealed how the typhoid toxin works to hijack DNA repair machines and accelerate the aging of cells, a breakthrough that could pave the way for new strategies to combat the killer disease.

6 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

$15 million grant funds new effort to develop universal vaccine for strep throat infections

CARB-X, an international non-profit partnership of private, academic and government institutions, has awarded SutroVax, Inc., a Northern California-based biopharmaceutical company, with an award of up to $15 million to develop a universal vaccine for Group A Streptococcus, the bacteria that causes pharyngitis or strep throat.

4 Sep 2019

Novel approach could help prevent sepsis in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient's skin, gastrointestinal tract, respiratory tracts and health care-related human contact.

4 Sep 2019

Pneumonia uses hydrogen peroxide to weaken the immune system

Pneumonia is a lung infection, filling up the alveoli with pus and fluid. At present, it’s the leading cause of death among children. The lung infection accounts for 15 percent of all deaths in children below five years old, killing more than 800,000 children in 2017 alone.

3 Sep 2019

Molecular mechanism by which human stomach pathogen is attracted to bleach revealed

Researchers at the University of Oregon have uncovered a molecular mechanism by which the human stomach pathogen Helicobacter pylori is attracted to bleach, also known as hypochlorous acid or HOCI.

30 Aug 2019

Cell-free DNA identifies pathogens and quantifies injuries to organs

A common problem in diagnosing infectious disease is that the presence of a potential pathogen in the body does not necessarily mean the patient is sick. This can be particularly challenging for the treatment of organ transplant recipients, who often grapple with infection as well as complications related to immunosuppression.

29 Aug 2019

A detailed map to understand how viruses infect human cells

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect.

29 Aug 2019

DNA vaccine for tick-borne disease ‘SFTS’ confers protection against lethal infection in ferrets

A KAIST research team reported the development of a DNA vaccine for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) which completely protects against lethal infection in ferrets.

29 Aug 2019

[BC]2 conference focuses on use of big data in molecular medicine

From 9 to 11 September, the [BC]2 Basel Computational Biology Conference, organized by the SIB Swiss Institute of Bioinformatics, will bring together international and Swiss-based scientists working in this field, in one of the key bioinformatics events in Europe: a prime opportunity to hear from leading experts, from precision oncology to infectious diseases.

29 Aug 2019

Promising vaccine may protect against the Klebsiella superbug

A powerful superbug, a hypervirulent form of the bacteria Klebsiella pneumoniae, is a very difficult to curb infection. It causes a variety of infections including rare but life-threatening liver, respiratory tract, bloodstream and other infections.

28 Aug 2019

Early detection method for pinpointing molecular signatures of Lyme disease

When researchers examined the mitochondrial DNA of Ötzi, a man entombed in ice high in the Tyrolean Alps some 5,300 years ago, they made a startling discovery.

26 Aug 2019

Researchers discover pivotal role for bacterial sex in evolution of mammalian microbiome

In a pioneer study now published in Proceedings of the National Academy of Science - USA, the research team led by Isabel Gordo, from the Instituto Gulbenkian de Ciência, in collaboration with researcher Michael Lässig of Cologne University, used healthy mice to study real-time gut colonization and discovered a pivotal role for bacterial sex in the evolution of the mammalian microbiome.

25 Aug 2019

New approach to detection reveals unreported Zika outbreak in 2017

Public health experts in the US have discovered that the Zika virus may still be spreading in the Americas, despite case reporting having approached close to zero.

23 Aug 2019

Lungs feed deadly bacteria in cystic fibrosis

In cystic fibrosis, Pseudomonas aeruginosa is a much-feared pathogen. The bacterium easily colonizes the lungs of people with cystic fibrosis, leading to chronic infections that are almost impossible to eradicate and are ultimately fatal.

22 Aug 2019

Northern Antibiotics working on a new molecule to fight antibiotic-resistant bacteria

Each year, around 60,000 deaths are caused by antibiotic-resistant bacteria in Europe and the U.S., and this number is growing.

21 Aug 2019

Humic substances extracted from coal can help fight viruses

Scientists from Russia demonstrated a novel approach leveraging the combination of high-resolution mass spectrometry and chemoinformatics to identify biologically active molecular components of humic substances extracted from coal, and discovered substances with antiviral activity against the tick-borne encephalitis virus.

19 Aug 2019

UVA scientists reveal how E. coli knows to cause the worst possible infections

A pair of University of Virginia School of Medicine scientists have revealed how E. coli seeks out the most oxygen-free crevices of your colon to cause the worst infection possible.

19 Aug 2019