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SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

Researchers at the Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona (IBB-UAB), in collaboration with the biopharmaceutical company SOM Biotech, located in the Barcelona Science Park (PCB), have published, in Nature Communications, the results of a drug repositioning study in which they describe a powerful drug, SOM0226 (tolcapone) that could significantly improve the pharmacological treatment of familial transthyretin amyloidosis (ATTR).

24 Feb 2016

UMMC surgeons develop a program to direct critically ill patients to appropriate treatment location

A team of surgeons at the University of Maryland Medical Center has developed a program that utilizes its Shock Trauma Center (STC) model to direct critically ill non-trauma patients to the appropriate treatment location and get them into an operating room and hospital intensive care unit (ICU) bed as quickly as possible.

24 Feb 2016

Novel unit can significantly speed access to specialized care for critically ill patients

A novel unit to care for critically ill patients significantly speeds access to specialized care, according to a new study by physician scientists at the University of Maryland School of Medicine and the University of Maryland Medical Center.

24 Feb 2016

New clinical manual addresses controversial topic of organ donation after euthanasia

A new practical manual addresses the controversial topic of organ donation after euthanasia, providing guidance to clinicians whose patients have requested euthanasia and the desire to offer their organs to others in need.

24 Feb 2016

Beiging of white fat could be harnessed to combat diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes. The team, led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania published their findings this month in the journal Diabetes.

18 Feb 2016

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

A reduction in the risks of infection- and organ failure-related death has driven an improvement in non-relapse mortality among recipients of allogeneic haematopoietic stem cell transplantation, Japanese research suggests.

17 Feb 2016

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

A study led by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key player contributing to the maintenance of hematopoietic stem cells (HSCs), blood cell precursors which have the ability to become any type of blood cell in the body.

17 Feb 2016

Study reveals another clue to workings of trachoma

Another clue to the workings of trachoma - the world's leading infectious cause of blindness - has been revealed in a new study published in BMC Infectious Diseases. Researchers identified markers of genetic regulation present in the early stages of infection that could predispose children to developing the condition in its long-term, severe form.

17 Feb 2016

Beige-fat formation could be harnessed to fight diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes.

17 Feb 2016

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

MemorialCare Health System announced today that it has entered into a joint venture partnership with Fresenius Medical Care North America to operate 15 dialysis clinics in Orange and Los Angeles counties. Thirteen of these clinics are fully operational and two additional clinics are being developed in San Juan Capistrano and Huntington Beach.

17 Feb 2016

Vanderbilt nephrologist building implantable artificial kidney with microchip filters

Vanderbilt University Medical Center nephrologist and associate professor of medicine Dr. William H. Fissell IV, is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient's own heart.

16 Feb 2016

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

A team of researchers led by scientists at St. Jude Children's Research Hospital is looking at ways to improve how blood-forming stem cells can be used for therapeutic interventions. The work has uncovered a group of genes that regulate how hematopoietic stem cells start to grow and thrive in mice. The function of many of these genes was previously unknown. Reconstitution of a robust blood-forming system is essential for recovery from many catastrophic diseases as well as from chemotherapy treatments.

16 Feb 2016

Anti-TNF therapy linked to ‘modest’ extra SCC risk

A Swedish population-based study shows that treatment with tumour necrosis factor inhibitors significantly increases the risk of developing squamous cell carcinoma, but not basal cell carcinoma, in patients with rheumatoid arthritis.

12 Feb 2016

Elsevier launches new open access journal: Transplantation Reports

Elsevier, a world-leading provider of scientific, technical, and medical information products and services today announces the launch of Transplantation Reports, a new online-only open access journal covering all areas of transplantation.

12 Feb 2016

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Researchers from Kumamoto University, Japan have identified a protein that limits the severity of Alport syndrome, a type of genetic kidney disease. The finding can provide clues that point toward new therapeutic approaches for Alport syndrome.

11 Feb 2016

Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

Johns Hopkins recently received approval from the United Network for Organ Sharing to be the first hospital in the U.S. to perform HIV-positive to HIV-positive organ transplants. The institution will be the first in the nation to do an HIV-positive to HIV-positive kidney transplant and the first in the world to execute an HIV-positive to HIV-positive liver transplant.

11 Feb 2016

UM SOM Dean E. Albert Reece, UMMS President and CEO Robert Chrencik named recipients of 'Speaker's Medallion'

The Maryland House of Delegates and House Speaker Michael E. Busch, has announced that University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA and University of Maryland Medical System President and CEO Robert Chrencik, MBA, are recipients of the "Speaker's Medallion," the highest honor given to the public by the leader of the Maryland House of Delegates.

11 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Study: Only one-third of patients receive living donor kidney transplant pre-emptively

A kidney transplant is a life-changing and life-saving procedure. Yet, a new study conducted by Mayo Clinic and the University of Michigan shows that only one-third of patients who ultimately receive a living donor kidney transplant receive it pre-emptively (i.e., before starting dialysis). Less than two-thirds receive a transplant either pre-emptively or within a year of starting dialysis.

9 Feb 2016

One million people across England, North Wales now registered to book blood donation appointments online

One million people across England and North Wales are now registered to book donation appointments online, making it one of the largest digital booking systems of any blood service in the world.

4 Feb 2016

Transplant News and Research

SOM0226 (tolcapone) drug could significantly improve pharmacological treatment of ATTR

UMMC surgeons develop a program to direct critically ill patients to appropriate treatment location

Novel unit can significantly speed access to specialized care for critically ill patients

New clinical manual addresses controversial topic of organ donation after euthanasia

Beiging of white fat could be harnessed to combat diabetes

Allo-HSCT Non-Relapse Related Mortality Reduction Revealed

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

Study reveals another clue to workings of trachoma

Beige-fat formation could be harnessed to fight diabetes

MemorialCare partners with Fresenius Medical Care to operate 15 dialysis clinics in Southern California

Vanderbilt nephrologist building implantable artificial kidney with microchip filters

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

Anti-TNF therapy linked to ‘modest’ extra SCC risk

Elsevier launches new open access journal: Transplantation Reports

Kumamoto University researchers identify protein that limits severity of Alport syndrome

Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

UM SOM Dean E. Albert Reece, UMMS President and CEO Robert Chrencik named recipients of 'Speaker's Medallion'

UC San Diego School of Medicine launches new NAFLD Research Center

Study: Only one-third of patients receive living donor kidney transplant pre-emptively

One million people across England, North Wales now registered to book blood donation appointments online

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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