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Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Influenza's ability to resist the effects of cheap and popular antiviral agents in Asia and Russia should serve as a cautionary tale about U.S. plans to use the antiviral Tamiflu in the event of widespread avian flu infection in humans, scientists say.

7 Jan 2009

Discovery of more efficient way to create induced Pluripotent Stem (iPS) cells

A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process.

7 Jan 2009

Bird flu becoming more resistant to antivirals

A new University of Colorado at Boulder study shows the resistance of the avian flu virus to a major class of antiviral drugs is increasing through positive evolutionary selection, with researchers documenting the trend in more than 30 percent of the samples tested.

7 Jan 2009

Framingham and National Cholesterol Education Program tools do not accurately predict coronary heart disease

The Framingham and National Cholesterol Education Program tools, NCEP, do not accurately predict coronary heart disease, according to a study performed at the Yale University School of Medicine in New Haven, CT.

6 Jan 2009

New understanding of seizure behaviors and epilepsy

Two children have a seizure. One child never has another seizure. Twenty years later, the other child has a series of seizures and is diagnosed with epilepsy.

6 Jan 2009

Virtuoso cell engineering

University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.

6 Jan 2009

Onyx Pharmaceuticals acquires license option on novel JAK2 inhibitors from S*BIO

Onyx Pharmaceuticals, Inc. has announced that it has acquired an option to license rights to SB1518, an orally available, potent, and selective inhibitor of Janus Kinase 2 (JAK2), and SB1578, also a JAK2 inhibitor, from S*BIO Pte Ltd based in Singapore.

6 Jan 2009

People with Ala12 gene variant need to watch out for high fat in their diets

New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication.

6 Jan 2009

Discovery of new way for bacteria to transfer toxic genes to unrelated bacterial species

In a laboratory experiment, the scientists from NYU School of Medicine discovered that Staphylococcus aureus, a notorious bacterium that causes toxic shock syndrome and many other types of infections and is the scourge of hospitals nationwide due to its growing antibiotic resistance, could co-opt viral parasites as secret pipelines for transferring toxin genes to vastly different bacterial species.

6 Jan 2009

Genetic mutation causes familial susceptibility for degenerative brain disease acute necrotizing encephalopathy

Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center - the nucleus - puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE).

6 Jan 2009

Innovative brain-scan technology helps visualize brain aging before symptoms appear

UCLA scientists have used innovative brain-scan technology developed at UCLA, along with patient-specific information on Alzheimer's disease risk, to help diagnose brain aging, often before symptoms appear.

6 Jan 2009

Bacteria discovered in amniotic fluids of women who undergo preterm birth

Researchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

6 Jan 2009

Research initiative looks at helpful bacteria found on the skin

The study of ancient microbes may not seem consequential, but such pioneering research at the University of Oklahoma has implications for the state of modern human health.

5 Jan 2009

Metadherin gene linked to metastasis of breast cancer

A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death.

5 Jan 2009

Genetic News and Research

Genomics in China

Gene mutations found to predict acute lymphoblastic leukemia relapse

Widespread antiviral drug use can accelerate the evolution of drug resistance in viruses

Discovery of more efficient way to create induced Pluripotent Stem (iPS) cells

Bird flu becoming more resistant to antivirals

Framingham and National Cholesterol Education Program tools do not accurately predict coronary heart disease

New understanding of seizure behaviors and epilepsy

Virtuoso cell engineering

Onyx Pharmaceuticals acquires license option on novel JAK2 inhibitors from S*BIO

People with Ala12 gene variant need to watch out for high fat in their diets

Discovery of new way for bacteria to transfer toxic genes to unrelated bacterial species

Genetic mutation causes familial susceptibility for degenerative brain disease acute necrotizing encephalopathy

Innovative brain-scan technology helps visualize brain aging before symptoms appear

Bacteria discovered in amniotic fluids of women who undergo preterm birth

Research initiative looks at helpful bacteria found on the skin

Metadherin gene linked to metastasis of breast cancer

New insight into critical molecular mechanisms involved in aggressive childhood cancer

Old Digitalis-based drugs show promise as a treatment for cancer

Metadherin gene plays dual role in breast cancers with poor prognosis

Antibodies take 'evolutionary leaps' to fight microbes

Genetics & Genomics - Second Edition eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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