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FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.

16 Aug 2018

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

The mechanics behind how an important process within the cell traps material before recycling it has puzzled scientists for years. But Penn State researchers have gained new insight into how this process seals off waste, much like a trash bag.

16 Aug 2018

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this.

16 Aug 2018

Mount Sinai study could transform treatment for patients with retinal degenerative diseases

Researchers at Mount Sinai have successfully restored vision in mice through activating retinal stem cells, something that has never been done before. Their study, published in the August 15 online issue of Nature, could transform treatment for patients with retinal degenerative diseases, which currently have no cure.

16 Aug 2018

Hearts of newborn piglets can completely heal after heart attacks

While pigs still cannot fly, researchers have discovered that the hearts of newborn piglets do have one remarkable ability. They can almost completely heal themselves after experimental heart attacks.

15 Aug 2018

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

A study of a large animal model of achromatopsia caused by a mutation in the CNGA3 gene that was treated with a single injection of CNGA3 gene therapy delivered using an AAV5 vector revealed findings reported long-term follow-up findings that show promise for the efficacy and safety of this therapeutic approach.

15 Aug 2018

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded spaces, and quickly coalesce into droplets - like oil in water.

15 Aug 2018

Study reveals role of RUNX proteins in DNA repair

A study by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia pathway.

15 Aug 2018

Researchers compare existing approaches for automating diagnostic procedures of skin lesions

The three prevalent skin cancers, according to the literature are melanoma, basal cell carcinoma and squamous cell carcinoma.

15 Aug 2018

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion.

15 Aug 2018

Newly discovered cytoskeleton utilized by cancer cells for survival

Researchers at Lund University in Sweden have discovered a cytoskeleton which provides the structure for mitochondria, the cell's energy producers.

15 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Cell News and Research

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

Mount Sinai study could transform treatment for patients with retinal degenerative diseases

Hearts of newborn piglets can completely heal after heart attacks

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Study reveals role of RUNX proteins in DNA repair

Researchers compare existing approaches for automating diagnostic procedures of skin lesions

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

Newly discovered cytoskeleton utilized by cancer cells for survival

Researchers discover new promising target point for cancer and diabetes therapies

New model of genetically engineered immune cells may help fight solid tumors

Porvair Sciences' new automation-friendly BactiGrowth plates

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Real-time dynamic monitoring of cell's nucleus for effective cancer screening

Scripps Research scientists uncover new approach for treating thrombocytopenia

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Seven activities that prevent you from getting quality sleep during summer

“Zombie gene” protects elephants from cancer finds study

What are the challenges of cell line development? eBook

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