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Pathogenic bacteria can block gut’s natural defense to spread infection

When harmful bacteria that cause food poisoning, such as E. coli, invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading.

22 Oct 2025

HMGN1 gene linked to heart problems in people with Down syndrome

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life.

22 Oct 2025

Study forces a textbook rewrite on cell division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025

Researchers gain new insights into aging based on studies in dogs

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

22 Oct 2025

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University of Technology, University of Queensland, and Nanjing Stomatological Hospital has introduced groundbreaking three-dimensional (3D) dynamic cell co-culture models to simulate metabolic dysfunction-associated steatotic liver disease (MASLD) progression stages.

22 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

The future of automation: Machine learning–driven hepatocyte and organoid counting

DeNovix discusses how customer demand inspired the development of specialized CellDrop applications for hepatocytes and organoids.

From DeNovix Inc. 22 Oct 2025

$VT3989 shows promising antitumor activity in refractory mesothelioma patients$

VT3989 shows promising antitumor activity in refractory mesothelioma patients

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led by researchers from The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Study shows mRNA-based COVID vaccines enhance effectiveness of immune checkpoint therapy

Patients with cancer who received mRNA-based COVID vaccines within 100 days of starting immune checkpoint therapy were twice as likely to be alive three years after beginning treatment, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Despite the hoopla, vaccines should be in reach this cough-and-cold season

For people whose autumn agenda includes getting vaccinated against respiratory diseases — covid, flu, and, for some, RSV — this year may be surprisingly routine.

22 Oct 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025

Gut bacteria found to make serotonin and boost intestinal motility

Researchers have identified Limosilactobacillus mucosae and Ligilactobacillus ruminis as human gut bacteria capable of producing serotonin by decarboxylating 5-hydroxytryptophan (5-HTP). Their activity enhances intestinal motility and enteric nerve density, linking microbial serotonin synthesis to gut function and potential IBS mechanisms.

21 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary human T cells, addressing a key manufacturing and scalability challenge in next-generation cell therapies.

21 Oct 2025